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ClinicalTrials.gov 50 recruiting now early-phase tilt #68 of 28,707 conditions

Neoplasms: early-phase trial registry

50 of 160 indexed Neoplasms trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #68 of 28,707 conditions by registered trial count.

160 US clinical trials · 50 currently recruiting · #68 of 28,707 conditions by registered trial count

Neoplasms: 160 US clinical trials tracked, 50 recruiting.

Neoplasms is the subject of 160 registered US clinical trials on ClinicalTrials.gov, 50 of them currently open to new participants. 9 are in Phase 3-4 (later-stage) and 99 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 15 of these trials.

Enrollment posture brief

Registry condition neoplasms

OPEN 50 | RECR 31% | LATE 9 | EARLY 99 | RANK #68 | SPON 15

Nearest open-share peer: Aortic Valve Disease (31% recruiting · 16 trials)

Gastric Cancer45.3%Neoplasms (this)31%Parkinson's Disease26.1%Bipolar Disorder22.7%Influenza17.2%
Open-enrollment share among volume-matched conditions near Neoplasms

Neoplasms lists 50 open slots (31% of 160 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Neoplasms on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Neoplasms is recruiting below its size-band peers.

    50 of 160 indexed trials (31.3%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Neoplasms trials is spread across many organizations.

    National Cancer Institute (NCI) accounts for 15 of 160 trials (9.4%). 85 distinct sponsors appear on at least one study for this condition label.

  3. Typical Neoplasms enrolment sits around 81 participants.

    Median target enrolment is 81 among the 159 trials that report a genuine target (sentinel values excluded). 87 of those (54.7%) plan for fewer than 100 participants.

  4. Neoplasms research is mostly interventional.

    130 interventional and 30 observational studies make up this index (81.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 181Phase 218Phase 37Phase 42

Open and recent trials

160 total, page 2 of 4

ACTIVE NOT RECRUITING NA 1,647 participants

Tomosynthesis vs. Contrast-Enhanced Mammography in Women With Personal History of Breast Cancer in Western Pennsylvania

Wendie Berg

NCT04085510

ACTIVE NOT RECRUITING Phase 3 831 participants

A Study of Encorafenib Plus Cetuximab With or Without Chemotherapy in People With Previously Untreated Metastatic Colorectal Cancer

Pfizer

NCT04607421

ACTIVE NOT RECRUITING Phase 3 785 participants

A Study to Evaluate Dostarlimab Plus Carboplatin-paclitaxel Versus Placebo Plus Carboplatin-paclitaxel in Participants With Recurrent or Primary Advanced Endometrial Cancer

Tesaro

NCT03981796

ACTIVE NOT RECRUITING Phase 1 730 participants

Study of TSR-042, an Anti-programmed Cell Death-1 Receptor (PD-1) Monoclonal Antibody, in Participants With Advanced Solid Tumors

Tesaro

NCT02715284

ACTIVE NOT RECRUITING Phase 1 463 participants

A Study of TSR-022 in Participants With Advanced Solid Tumors (AMBER)

Tesaro

NCT02817633

ACTIVE NOT RECRUITING Phase 1 413 participants

A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of JNJ-63723283, an Anti-PD-1 Monoclonal Antibody, in Participants With Advanced Cancers

Janssen Research & Development

NCT02908906

ACTIVE NOT RECRUITING Phase 1 301 participants

A Study of E7386 in Combination With Other Anticancer Drug(s) in Participants With Solid Tumor

Eisai

NCT04008797

ACTIVE NOT RECRUITING Phase 3 300 participants

Studying the Effect of Denosumab on Preventing Breast Cancer in Women With a BRCA1 Germline Mutation

Alliance for Clinical Trials in Oncology

NCT04711109

ACTIVE NOT RECRUITING Phase 2 237 participants

Extended Access of Momelotinib in Adults With Myelofibrosis

GlaxoSmithKline

NCT03441113

ACTIVE NOT RECRUITING 232 participants

M7824 Related Adverse Effects in Adults With Cancer

National Cancer Institute (NCI)

NCT04267861

ACTIVE NOT RECRUITING Phase 3 200 participants

A Rollover Study of Alectinib in Patients With Anaplastic Lymphoma Kinase (ALK)-Positive or Rearranged During Transfection (RET)-Positive Cancer

Hoffmann-La Roche

NCT03194893

ACTIVE NOT RECRUITING Phase 1 158 participants

A Study of Amivantamab Subcutaneous (SC) Administration for the Treatment of Advanced Solid Malignancies

Janssen Research & Development

NCT04606381

ACTIVE NOT RECRUITING Phase 1 152 participants

First-Time-in-Human Study of GSK4381562 in Participants With Advanced Solid Tumors

GlaxoSmithKline

NCT05277051

ACTIVE NOT RECRUITING Phase 1 151 participants

A Study to Test BI 765179 Alone and in Combination With Ezabenlimab in Patients With Advanced Cancer (Solid Tumors) and BI 765179 in Combination With Pembrolizumab in Patients With Advanced Head and Neck Cancer

Boehringer Ingelheim

NCT04958239

ACTIVE NOT RECRUITING Phase 2 120 participants

Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1)

Aadi Bioscience

NCT05103358

ACTIVE NOT RECRUITING Phase 1 107 participants

Study of the Safety and Effectiveness of GSK6097608 in Participants With Advanced Solid Tumors

GlaxoSmithKline

NCT04446351

ACTIVE NOT RECRUITING Phase 2 103 participants

Master Protocol to Assess the Safety and Antitumor Activity of Genetically Engineered T Cells in NY-ESO-1 and/or LAGE-1a Positive Solid Tumors

Uswm CT

NCT03967223

ACTIVE NOT RECRUITING Phase 1 97 participants

A First Time in Human (FTIH) Study of GSK3745417 Administered to Participants With Advanced Solid Tumors

GlaxoSmithKline

NCT03843359

ACTIVE NOT RECRUITING Phase 2 87 participants

Study to Evaluate Safety and Antitumor Activity of Lete-Cel (GSK3377794) in HLA-A2+ Participants With NY-ESO-1 Positive Previously Treated Advanced (Metastatic or Unresectable) Synovial Sarcoma or Myxoid/Round Cell Liposarcoma

Uswm CT

NCT06703346

ACTIVE NOT RECRUITING 80 participants

Digitally-Captured Step Counts for Evaluating Performance Status in Advanced Cancer Patients

Cedars-Sinai Medical Center

NCT03757182

ACTIVE NOT RECRUITING NA 58 participants

Hispanic Adapted and Culturally Relevant Exercising Together

University of Arizona

NCT06018311

ACTIVE NOT RECRUITING NA 50 participants

Time-Restricted Eating to Address Persistent Cancer-Related Fatigue

University of Maryland, Baltimore

NCT05256888

ACTIVE NOT RECRUITING Phase 1 43 participants

Study of CAR-T Cells Expressing CD30 and CCR4 for r/r CD30+ HL and CTCL

UNC Lineberger Comprehensive Cancer Center

NCT03602157

ACTIVE NOT RECRUITING Phase 1 42 participants

A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK), and Preliminary Anticancer Activity of GSK4524101 Alone or With Niraparib in Participants With Solid Tumors

GlaxoSmithKline

NCT06077877

ACTIVE NOT RECRUITING Phase 1 38 participants

Study of CD30 CAR for Relapsed/Refractory CD30+ HL and CD30+ NHL

UNC Lineberger Comprehensive Cancer Center

NCT02690545

ACTIVE NOT RECRUITING Phase 2 21 participants

Bevacizumab in Adults With Recurrent Respiratory Papillomatosis (RRP)

National Cancer Institute (NCI)

NCT05797246

ACTIVE NOT RECRUITING Phase 1 18 participants

Administration of T Lymphocytes for Prevention of Relapse of Lymphomas

UNC Lineberger Comprehensive Cancer Center

NCT02663297

ACTIVE NOT RECRUITING Phase 2 7 participants

Study to Evaluate Safety and Antitumor Activity of Lete-Cel (GSK3377794) in HLA-A2+ Participants With NY-ESO-1 Positive Previously Untreated Advanced (Metastatic or Unresectable) Synovial Sarcoma and Myxoid/Round Cell Liposarcoma

USWM, LLC (dba US WorldMeds)

NCT05993299

COMPLETED 1,400 participants

Concordance Between ctDNA Assay and FoundationOne

Foundation Medicine

NCT02620527

COMPLETED Phase 3 866 participants

Nab-paclitaxel and Gemcitabine vs Gemcitabine Alone as Adjuvant Therapy for Patients With Resected Pancreatic Cancer (the "Apact" Study)

Celgene

NCT01964430

COMPLETED Phase 3 755 participants

XRP6258 Plus Prednisone Compared to Mitoxantrone Plus Prednisone in Hormone Refractory Metastatic Prostate Cancer

Sanofi

NCT00417079

COMPLETED Phase 1 610 participants

A Study to Assess the Safety and Pharmacokinetics of MOXR0916 and Atezolizumab (Also Known as MPDL3280A or Anti-PD-L1) in Participants With Locally Advanced or Metastatic Solid Tumors

Genentech

NCT02410512

COMPLETED Phase 2 440 participants

REST: Reducing End-of-Life Symptoms With Touch

National Center for Complementary and Integrative Health (NCCIH)

NCT00065195

COMPLETED NA 358 participants

Enhanced Self-Efficacy Training

Duke University

NCT00938769

COMPLETED 300 participants

Views of Cancer Patients Regarding Financial Conflicts of Interest

National Institutes of Health Clinical Center (CC)

NCT00097682

COMPLETED Phase 1 266 participants

This Study Aims to Find the Best Dose of BI 907828 (Brigimadlin) in Patients With Different Types of Advanced Cancer (Solid Tumors)

Boehringer Ingelheim

NCT03449381

COMPLETED NA 258 participants

Addressing Cancer-Related Financial Toxicity in Rural Oncology Care Settings

UNC Lineberger Comprehensive Cancer Center

NCT04931251

COMPLETED 242 participants

Human Leukocyte Antigen Typing and Tumor Antigen Expression Profiling

Immatics US

NCT03760952

COMPLETED Phase 1 236 participants

Crossover Study to Assess the Relative Bioavailability and Bioequivalence of Niraparib Tablet Compared to Niraparib Capsule

Tesaro

NCT03329001

COMPLETED Phase 1 229 participants

A Study of LY2880070 in Participants With Advanced or Metastatic Cancer

Esperas Pharma

NCT02632448

COMPLETED Phase 3 221 participants

Multimodal Intervention for Cachexia in Advanced Cancer Patients Undergoing Chemotherapy

Norwegian University of Science and Technology

NCT02330926

COMPLETED 214 participants

Combined F-18 NaF and F-18 FDG PET/CT for Evaluation of Malignancy

Stanford University

NCT00725387

COMPLETED Phase 1 174 participants

A Study to Assess Safety and Pharmacokinetics of MOXR0916 in Participants With Locally Advanced or Metastatic Solid Tumors

Genentech

NCT02219724

COMPLETED Phase 1 170 participants

A Study in Metastatic Cancer and Advanced or Metastatic Unresectable Pancreatic Cancer

Eli Lilly and Company

NCT01373164

COMPLETED NA 154 participants

Outlook: An Intervention to Improve Quality of Life in Serious Illness

Duke University

NCT00939146

COMPLETED NA 140 participants

Exercise Intervention for LGBT Cancer Survivors

University of Rochester

NCT02459769

COMPLETED Phase 1 138 participants

A Study Of PF-06647020 For Adult Patients With Advanced Solid Tumors

Pfizer

NCT02222922

COMPLETED Phase 1 133 participants

This Study in Patients With Different Types of Cancer (Solid Tumours) Aims to Find a Safe Dose of Xentuzumab in Combination With Abemaciclib With or Without Hormonal Therapies. The Study Also Tests How Effective These Medicines Are in Patients With Lung and Breast Cancer

Boehringer Ingelheim

NCT03099174

COMPLETED NA 123 participants

A Treatment Protocol For Patients Continuing From A Prior SU011248 Protocol.

Pfizer

NCT00443534

COMPLETED 121 participants

Livestrong Cancer Institutes' Patient Reported Outcomes Study

University of Texas at Austin

NCT04627077

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Phase Distribution

PhaseTrial count
Phase 1 81
Phase 2 18
Phase 3 7
Phase 4 2

Named interventions

Most-linked intervention names on Neoplasms records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Gemcitabine Drug
5 trials
Placebo Drug
5 trials
Fludarabine Drug
4 trials
Cyclophosphamide Drug
4 trials
Dostarlimab Drug
3 trials
Belrestotug Drug
2 trials
GSK5764227 Drug
2 trials
Dostarlimab Biological
2 trials

US sites by state

Facility locations filed on Neoplasms trials. A trial with sites in several states counts in each.

California 53 trials
Texas 46 trials
Florida 36 trials
New York 31 trials
Maryland 31 trials
Colorado 31 trials
Michigan 28 trials
Illinois 26 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Neoplasms page

160 registered trials, 50 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Neoplasms condition card totals 160 registered trials; most-linked intervention Gemcitabine; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.