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NCT07276373 · ClinicalTrials.gov registry record · Phase 1

Two Part Study of Nenocorilant Combined With Nivolumab in Patients With Advanced Solid Malignancies

A Phase 1 study of Neoplasms, sponsored by Corcept Therapeutics.

Recruiting
Registry status
Phase 1
Development phase
50
Enrollment target
3
Study locations

NCT07276373 is a Phase 1 study of Neoplasms that is actively recruiting participants, run by Corcept Therapeutics. The registered enrollment target is 50 participants, below the 1,621-participant average among 158 other Neoplasms trials with a reported enrollment target (97% lower). The trial reports 3 study locations across 3 states.

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The verdict

NCT07276373, a Phase 1 study of Neoplasms, is actively recruiting participants, sponsored by Corcept Therapeutics.

RECRUITING
Registry status
Phase 1
Development phase
50 participants
Enrollment target
3
Study locations

Study Summary

This open-label, dose-finding, and proof of concept study will evaluate the safety, tolerability, maximum-tolerated dose (MTD) and/or optimal dose of nenocorilant when administered in combination with nivolumab in patients with advanced solid malignancies.

Conditions Studied

Interventions

  • DRUG Nivolumab
  • DRUG Nenocorilant 200 mg
  • DRUG Nenocorilant 300 mg
  • DRUG Nenocorilant 400 mg

Study Locations (3)

California

  • Site 03 - Los Angeles

Texas

  • Site 01 - San Antonio

Utah

  • Site 02 - West Valley City

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2026-01-16
Est. Completion 2027-01
Phase Phase 1

Sponsor

Corcept Therapeutics

54 total trials

What the Registry Record Tells You About NCT07276373

The ClinicalTrials.gov registry entry for NCT07276373 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,621-participant average among 158 other Neoplasms trials with a reported enrollment target (97% lower). The listed sponsor is Corcept Therapeutics, which has 54 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Neoplasms appearing as the primary indexed condition, and to 4 interventions - of which Nivolumab is the first listed.

NCT07276373 reports 3 study locations spanning 3 distinct geographic areas - top geographies include California, Texas, Utah.

Frequently Asked Questions

What is clinical trial NCT07276373 about?

NCT07276373 is a clinical study titled "Two Part Study of Nenocorilant Combined With Nivolumab in Patients With Advanced Solid Malignancies". This open-label, dose-finding, and proof of concept study will evaluate the safety, tolerability, maximum-tolerated dose (MTD) and/or optimal dose of nenocorilant when administered in combination with nivolumab in patients with advanced solid malignancies.

What is the current status of trial NCT07276373?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 50 participants. The study started on 2026-01-16. Estimated completion is 2027-01.

What conditions does trial NCT07276373 study?

This clinical trial studies the following conditions: Neoplasms.

What interventions are being tested in trial NCT07276373?

The interventions under investigation include: Nivolumab (DRUG), Nenocorilant 200 mg (DRUG), Nenocorilant 300 mg (DRUG), Nenocorilant 400 mg (DRUG).

Who is sponsoring clinical trial NCT07276373?

This trial is sponsored by Corcept Therapeutics, which has 54 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07276373 being conducted?

This trial has 3 study locations across California, Texas, Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.