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Biennial CEM in Women With a Personal History of Breast Cancer
NCT06105749 · View on ClinicalTrials.gov ↗
Study Summary
This is a prospective clinical trial that will examine if biennial contrast-enhanced mammography added to annual 3D mammography (tomosynthesis) substantially improves breast cancer detection with minimal increase in false-positives, in women with a personal history of breast cancer.
Conditions Studied
Interventions
- DEVICE contrast-enhanced mammography
Study Locations (6)
Pennsylvania
- UPMC Magee-Womens Imaging - Bethel Park — Bethel Park
- UPMC Magee at the Lemieux Sports Complex — Cranberry Township
- Magee Womancare Monroeville — Monroeville
- Magee-Womens Hospital — Pittsburgh
- Hillman Cancer Center at Shadyside — Pittsburgh
- UPMC West Mifflin Outpatient Center — West Mifflin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,500 participants |
| Start Date | 2023-11-08 |
| Est. Completion | 2031-04 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06105749
The ClinicalTrials.gov registry entry for NCT06105749 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 1,500 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Wendie Berg, which has 2 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 4 conditions, with Breast Cancer appearing as the primary indexed condition, and to 1 intervention — of which contrast-enhanced mammography is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06105749 reports 6 study locations spanning 1 distinct geographic area — top geographies include Pennsylvania. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06105749 about?
NCT06105749 is a clinical study titled "Biennial CEM in Women With a Personal History of Breast Cancer". This is a prospective clinical trial that will examine if biennial contrast-enhanced mammography added to annual 3D mammography (tomosynthesis) substantially improves breast cancer detection with minimal increase in false-positives, in women with a personal history of breast cancer.
What is the current status of trial NCT06105749?
This trial is currently recruiting. It is a NA study. The enrollment target is 1,500 participants. The study started on 2023-11-08. Estimated completion is 2031-04.
What conditions does trial NCT06105749 study?
This clinical trial studies the following conditions: Breast Cancer, Neoplasms, Breast Neoplasms, Breast Cancer Female. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06105749?
The interventions under investigation include: contrast-enhanced mammography (DEVICE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06105749?
This trial is sponsored by Wendie Berg, which has 2 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06105749 being conducted?
This trial has 6 study locations across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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