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NCT04442724 · ClinicalTrials.gov registry record · NA
Bladder Fiducial Markers and Multiparametric-MRI (Mp-MRI) to Optimize Bladder Chemo-radiotherapy
A NA study of Bladder Cancer and Neoplasms, sponsored by Cedars-Sinai Medical Center.
- Recruiting
- Registry status
- NA
- Development phase
- 60
- Enrollment target
- 3
- Study locations
NCT04442724: Recruiting NA study of Bladder Cancer and Neoplasms, sponsored by Cedars-Sinai Medical Center.
NCT04442724 is a NA study of Bladder Cancer and Neoplasms that is actively recruiting participants, run by Cedars-Sinai Medical Center. The registered enrollment target is 60 participants, below the 12,753-participant average among 175 other Bladder Cancer trials with a reported enrollment target (100% lower). The trial reports 3 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04442724, a NA study of Bladder Cancer and Neoplasms, is actively recruiting participants, sponsored by Cedars-Sinai Medical Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
- 3
- Study locations
Study Summary
The purpose of this study is to examine the usefulness of implanting small 24-K gold fiducial markers around a bladder tumor site, so that a Radiation Oncologist can identify the original tumor location at the time of radiation treatment. Other goals of the study include assessing whether a new MRI imaging technology can help with detection of bladder cancer earlier and more accurately when evidence of bladder cancer is not visible by scope.
Primary Outcome
Change in bladder volumes targeted for high dose radiation (HDR) between the first (Baseline) dose volume histogram (DVH) without the fiducial markers present, compared to the second DVH made after placement of the fiducial markers
Conditions Studied
Interventions
- PROCEDURE Fiducial marker placement
- DIAGNOSTIC_TEST Multiparametric MRI (mpMRI)
Study Locations (3)
California
- Cedars-Sinai Medical Center (CSMC) - Los Angeles
- University of California Los Angeles - Los Angeles
Massachusetts
- Harvard School of Medicine/Massachusetts General Hospital (MGH) - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2020-07-01 |
| Est. Completion | 2026-06-30 |
| Phase | NA |
What NCT04442724 shows while recruiting
NCT04442724 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 12,753-participant average among 175 other Bladder Cancer trials with a reported enrollment target (100% lower).
The record links to 5 conditions, with Bladder Cancer appearing as the primary indexed condition, and to 2 interventions - of which Fiducial marker placement is the first listed.
NCT04442724 reports a single indexed study location in California, Massachusetts.
Frequently Asked Questions
What is clinical trial NCT04442724 about?
NCT04442724 is a clinical study titled "Bladder Fiducial Markers and Multiparametric-MRI (Mp-MRI) to Optimize Bladder Chemo-radiotherapy". The purpose of this study is to examine the usefulness of implanting small 24-K gold fiducial markers around a bladder tumor site, so that a Radiation Oncologist can identify the original tumor location at the time of radiation treatment. Other goals of the study include assessing whether a new MRI ...
What is the current status of trial NCT04442724?
This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2020-07-01. Estimated completion is 2026-06-30.
What conditions does trial NCT04442724 study?
This clinical trial studies the following conditions: Bladder Cancer, Neoplasms, Urologic Neoplasms, Urinary Bladder Neoplasm, Urinary Bladder Diseases.
What interventions are being tested in trial NCT04442724?
The interventions under investigation include: Fiducial marker placement (PROCEDURE), Multiparametric MRI (mpMRI) (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT04442724?
This trial is sponsored by Cedars-Sinai Medical Center, which has 339 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04442724 being conducted?
This trial has 3 study locations across California, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04442724's enrollment target sits among peer trials
60 106th of 175 higher than 70 of 175 other Bladder Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Bladder Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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