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NCT04673942 · ClinicalTrials.gov registry record · Phase 2

A Study of AdAPT-001 in Subjects With Sarcoma and Refractory Solid Tumors

A Phase 2 study of Cancer and Neoplasms, sponsored by EpicentRx.

Recruiting
Registry status
Phase 2
Development phase
140
Enrollment target
6
Study locations

NCT04673942 is a Phase 2 study of Cancer and Neoplasms that is actively recruiting participants, run by EpicentRx. The registered enrollment target is 140 participants, below the 3,491-participant average among 615 other Cancer trials with a reported enrollment target (96% lower). The trial reports 6 study locations across 3 states.

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The verdict

NCT04673942, a Phase 2 study of Cancer and Neoplasms, is actively recruiting participants, sponsored by EpicentRx.

RECRUITING
Registry status
Phase 2
Development phase
140 participants
Enrollment target
6
Study locations

Study Summary

AdAPT-001 is an oncolytic virus that is injected directly into the tumor or via intraarterial administration. The purpose of this study is to find out if AdAPT-001 is safe and tolerable. The next step is to find out if AdAPT-001 if efficacious with or without a checkpoint inhibitor.

Interventions

  • DRUG Checkpoint Inhibitor, Immune
  • BIOLOGICAL AdAPT-001

Study Locations (6)

California

  • City of Hope - Duarte
  • California Cancer Associates for Research and Excellence, cCARE - San Marcos
  • Providence Saint John's Health Center - Santa Monica

Texas

  • Mary Crowley Cancer Research - Dallas
  • MD Anderson Cancer Center - Houston

Ohio

  • Cleveland Clinic - Cleveland

Trial Details

FieldValue
Enrollment Target 140 participants
Start Date 2021-03-29
Est. Completion 2027-03-01
Phase Phase 2

Sponsor

EpicentRx

15 total trials

What the Registry Record Tells You About NCT04673942

The ClinicalTrials.gov registry entry for NCT04673942 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 140 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 3,491-participant average among 615 other Cancer trials with a reported enrollment target (96% lower). The listed sponsor is EpicentRx, which has 15 total studies on file at ClinicalTrials.gov.

The record links to 6 conditions, with Cancer appearing as the primary indexed condition, and to 2 interventions - of which Checkpoint Inhibitor, Immune is the first listed.

NCT04673942 reports 6 study locations spanning 3 distinct geographic areas - top geographies include California, Texas, Ohio.

Frequently Asked Questions

What is clinical trial NCT04673942 about?

NCT04673942 is a clinical study titled "A Study of AdAPT-001 in Subjects With Sarcoma and Refractory Solid Tumors". AdAPT-001 is an oncolytic virus that is injected directly into the tumor or via intraarterial administration. The purpose of this study is to find out if AdAPT-001 is safe and tolerable. The next step is to find out if AdAPT-001 if efficacious with or without a checkpoint inhibitor.

What is the current status of trial NCT04673942?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 140 participants. The study started on 2021-03-29. Estimated completion is 2027-03-01.

What conditions does trial NCT04673942 study?

This clinical trial studies the following conditions: Cancer, Neoplasms, Sarcoma, Solid Tumor, Adult, Chondrosarcoma.

What interventions are being tested in trial NCT04673942?

The interventions under investigation include: Checkpoint Inhibitor, Immune (DRUG), AdAPT-001 (BIOLOGICAL).

Who is sponsoring clinical trial NCT04673942?

This trial is sponsored by EpicentRx, which has 15 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04673942 being conducted?

This trial has 6 study locations across California, Ohio, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.