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A Study of JNJ-87704916, as Monotherapy and in Combination for Advanced Solid Tumors
NCT06311578 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this study is to determine the safety, feasibility, recommended dose(s) and regimen(s) of JNJ-87704916 as monotherapy and in combination with cetrelimab.
Conditions Studied
Interventions
- DRUG Cetrelimab
- DRUG JNJ-87704916
Study Locations (10)
Other
- Gustave Roussy — Villejuif
- Hosp Univ Vall D Hebron — Barcelona
- Hosp Univ Fund Jimenez Diaz — Madrid
- Hosp Univ Hm Sanchinarro — Madrid
Pennsylvania
- Fox Chase Cancer Center — Philadelphia
- UPMC Cancer Centers — Pittsburgh
New York
- NYU Langone Health — New York
Texas
- MD Anderson Cancer Center — Houston
Ontario
- Toronto General Hospital — Toronto
Quebec
- Centre Hospitalier de l'Universite de Montreal — Montreal
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 96 participants |
| Start Date | 2024-04-10 |
| Est. Completion | 2032-08-26 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06311578
The ClinicalTrials.gov registry entry for NCT06311578 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 96 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Johnson & Johnson Enterprise Innovation, which has 5 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Neoplasms appearing as the primary indexed condition, and to 2 interventions — of which Cetrelimab is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06311578 reports 10 study locations spanning 6 distinct geographic areas — top geographies include Other, Pennsylvania, New York. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06311578 about?
NCT06311578 is a clinical study titled "A Study of JNJ-87704916, as Monotherapy and in Combination for Advanced Solid Tumors". The purpose of this study is to determine the safety, feasibility, recommended dose(s) and regimen(s) of JNJ-87704916 as monotherapy and in combination with cetrelimab.
What is the current status of trial NCT06311578?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 96 participants. The study started on 2024-04-10. Estimated completion is 2032-08-26.
What conditions does trial NCT06311578 study?
This clinical trial studies the following conditions: Neoplasms. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06311578?
The interventions under investigation include: Cetrelimab (DRUG), JNJ-87704916 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06311578?
This trial is sponsored by Johnson & Johnson Enterprise Innovation, which has 5 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06311578 being conducted?
This trial has 10 study locations across New York, Pennsylvania, Texas, Ontario, Quebec. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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