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2026 data Public-data reference. official source

Myocardial Ischemia

Open-data reference.

31 US clinical trials · 4 currently recruiting

Active & Recent Trials

RECRUITING NA 1,000 participants

Smartphone Twelve-Lead ECG Utility In ST-Elevation Myocardial Infarction II

AliveCor

NCT06271577

RECRUITING NA 700 participants

A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)

Fundación EPIC

NCT07286578

RECRUITING NA 70 participants

Bright Light Exposure in Surgical Patients

University of Colorado, Denver

NCT03822949

RECRUITING Phase 1 40 participants

Effect of Dapagliflozin on Microvascular Function in Women With Symptoms of Coronary Artery Disease

University of Virginia

NCT05762952

ACTIVE NOT RECRUITING NA 5,269 participants

Secondary Event Prevention Using Population Risk Management After PCI and for Anti-Rheumatic Medications

VA Office of Research and Development

NCT02694185

ACTIVE NOT RECRUITING NA 206 participants

A Single Center Diagnostic, Cross-sectional Study of Coronary Microvascular Dysfunction

NYU Langone Health

NCT03537586

COMPLETED Phase 3 15,526 participants

An Efficacy and Safety Study for Rivaroxaban in Patients With Acute Coronary Syndrome

Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

NCT00809965

COMPLETED Phase 3 8,000 participants

SYNERGY: Open Study of Enoxaparin Versus Unfractionated Heparin in Patients With Acute Coronary Syndromes

Sanofi

NCT00043784

COMPLETED 6,000 participants

ECG Methods for the Prompt Identification of Coronary Events

University of Pittsburgh

NCT04237688

COMPLETED NA 5,179 participants

International Study of Comparative Health Effectiveness With Medical and Invasive Approaches (ISCHEMIA)

NYU Langone Health

NCT01471522

COMPLETED 5,034 participants

XIENCE V® Everolimus Eluting Coronary Stent System USA Post-Approval Study (XIENCE V® USA Long Term Follow-up Cohort)

Abbott Medical Devices

NCT01120379

COMPLETED NA 5,000 participants

Clinical Decision Support for Medication Management and Adherence

Duke University

NCT00979225

COMPLETED Phase 3 3,000 participants

A Safety and Efficacy Study to Confirm the Cardioprotective Effects of MC-1 in Patients Undergoing High-Risk CABG

Medicure

NCT00402506

COMPLETED 2,349 participants

Stress CMR Perfusion Imaging in the United States (SPINS) Study

Society for Cardiovascular Magnetic Resonance

NCT03192891

COMPLETED 2,067 participants

An Observational Study of Cholesterol in Coronary Arteries

Infraredx

NCT00831116

COMPLETED Phase 4 777 participants

ISCHEMIA-Chronic Kidney Disease Trial

NYU Langone Health

NCT01985360

COMPLETED Phase 2 321 participants

ACT34-CMI -- Adult Autologous CD34+ Cells

Lisata Therapeutics

NCT00300053

COMPLETED Phase 2 300 participants

Safety and Efficacy of TP10, a Complement Inhibitor, in Adult Women Undergoing Cardiopulmonary Bypass Surgery

Avant Immunotherapeutics

NCT00082121

COMPLETED NA 287 participants

Collaborative Cardiac Care Project

US Department of Veterans Affairs

NCT00105664

COMPLETED Phase 3 250 participants

Safety and Efficacy of MCG for Diagnosing Coronary Heart Disease

Mayo Clinic

NCT00170027

COMPLETED NA 170 participants

Sapphire 3 CTO Study

OrbusNeich

NCT06358508

COMPLETED Phase 2 110 participants

Custodiol-HTK (Histidine-tryptophan-ketoglutarate) Solution as a Cardioplegic Agent

Marc Sakwa, MD

NCT01681095

COMPLETED NA 93 participants

AngioSculpt® Coronary Bifurcation Study

AngioScore

NCT00686647

COMPLETED Phase 3 71 participants

Electromechanical Mapping to Evaluate Heart Muscle

National Heart, Lung, and Blood Institute (NHLBI)

NCT00001895

COMPLETED NA 60 participants

A Comparison of the Effects of Intraoperative Administration of Metoprolol or Esmolol on General Anesthetic Requirement

University of Oklahoma

NCT00756236

COMPLETED NA 39 participants

Clinical Evaluation of Cardiac Output Estimation Based on Pulse Wave Transit Time

University of California, San Francis

NCT01877941

COMPLETED NA 37 participants

Data Analyses for Ancillary WISE Femhrt Hormone Replacement Study

Cedars-Sinai Medical Center

NCT00600106

COMPLETED Phase 2 25 participants

Nitric Oxide Inhalation Therapy to Relieve Chest Pain in Patients With Coronary Artery Disease

National Heart, Lung, and Blood Institute (NHLBI)

NCT00014040

COMPLETED Phase 3 12 participants

Precision of the Magnetocardiographer for Data Aquision and Analysis.

Mayo Clinic

NCT00170014

COMPLETED Phase 2 6 participants

Ranolazine Mediated PVC Reduction in Ischemic Heart Disease

Kent Hospital, Rhode Island

NCT02360397

COMPLETED NA

The Effect of Exercise Training on Mental Stress-Induced Silent Ischemia

US Department of Veterans Affairs

NCT00018252

Phase Distribution

PhaseTrial count
Early Phase 1 1
Phase 2 5
Phase 3 6
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Myocardial Ischemia Trial Landscape

ClinicalTrials.gov lists 31 US studies indexed under Myocardial Ischemia, and 4 of those are currently open to recruitment — roughly 13% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Myocardial Ischemia shows 7 late-stage studies (Phase 3 and Phase 4 combined) alongside 6 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Myocardial Ischemia is led by NYU Langone Health with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 31 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Myocardial Ischemia?

PlainTrial tracks 31 US clinical trials for Myocardial Ischemia, of which 4 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Myocardial Ischemia?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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