Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Alcohol Use Disorder (AUD)
Open-data reference.
31 US clinical trials · 22 currently recruiting
Active & Recent Trials
Combining a Smartphone App With Medications to Manage Heavy Drinking
VA Office of Research and Development
NCT06303778
Pharmaceutically-Enhanced Reinforcement for Reduced Alcohol and Smoking
Washington State University
NCT05181891
The Zonisamide and Reinforcement for Reducing Alcohol Use (ZARRA) Study
Washington State University
NCT05134857
The Oklahoma Parent-Child Assistance Program
University of Oklahoma
NCT05534568
Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics
Yale University
NCT06624137
Alcohol and the Social Brain: An Alcohol-Administration Hyperscanning Study Employing a Within-Subject Design
University of Illinois at Urbana-Champaign
NCT07125534
Alpha-1 Blockade for Alcohol Use Disorder (AUD)
Brown University
NCT04135846
Suvorexant for Alcohol Use Disorder (AUD): Neural Mechanisms
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NCT06484075
Probenecid Administration for Alcohol Craving and Consumption
Brown University
NCT07118618
MPFC Theta Burst Stimulation as a Treatment Tool for Alcohol Use Disorder: Effects on Drinking and Incentive Salience
Medical University of South Carolina
NCT04998916
Recovery Through Inhibitory Learning, Self-Efficacy Building, Problem Solving, and Community Building
University of Rhode Island
NCT07217795
Suvorexant for Treatment of AUD and PTSD
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
NCT06679062
The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)
Yale University
NCT06070649
Influence of Mavoglurant on Alcohol Craving and Drinking in Heavy Drinkers
Yale University
NCT06136195
iTBS for Alcohol Use Disorder
Nicholas Balderston, PhD
NCT06696365
Psilocybin With Psychological Support (Psi-PS) for Military Veterans and First Responders With Co-occurring PTSD & Alcohol Use Disorder (AUD)
Nathan Brashares Sackett
NCT06853912
Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 3 Semaglutide
Yale University
NCT07040592
Developing a Music Listening mHealth Intervention for Stress Reduction in Early Recovery
Washington State University
NCT07052318
Renewed Recovery: a Pilot Test of a Web-Based Mindfulness-Based Relapse Prevention Continuing Care Intervention for Alcohol Use Disorder
University of Georgia
NCT06987526
Diclofenac Dose Response Study
University of Maryland, Baltimore
NCT06636227
Study of Tirzepatide for Recovery and Alcohol Use Management
Brigham and Women's Hospital
NCT06727331
Effect of Sublingual Formulation of Dexmedetomidine Hydrochloride (HCl) (BXCL501) - Outpatient Study
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
NCT06335407
Comprehensive Process Model of AA-related Behavior Change
University of New Mexi
NCT04618653
A Study to Investigate the Safety and Efficacy of TMP-301 Compared to Placebo in Adult Patients With Alcohol Use Disorder
Tempero Bio
NCT06648655
RECLAIM STUDY: A Phase 2 Evaluating the Efficacy and Safety of Pemvidutide in the Treatment of Alcohol Use Disorder (AUD) in Subjects With Obesity or Overweight
Altimmune
NCT06987513
Ibudilast for Treating Alcohol Use Disorder
University of Pennsylvania
NCT05414240
Alcohol Telemedicine Consultation in Primary Care (ATC)
Kaiser Permanente
NCT05252221
Michigan SPARC Trial
Kaiser Permanente
NCT04861792
A Randomized, Double-blind Placebo-Controlled Pharmacogenetic Study of Topiramate in European-American Heavy Drinkers
University of Pennsylvania
NCT02371889
Brain Inflammation and Function in Alcoholism
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NCT02233868
Brain Network Modulation and Alcohol Use
Virginia Polytechnic Institute and State University
NCT04828577
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 6 |
| Phase 2 | 12 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Alcohol Use Disorder (AUD) Trial Landscape
ClinicalTrials.gov lists 31 US studies indexed under Alcohol Use Disorder (AUD), and 22 of those are currently open to recruitment — roughly 71% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Alcohol Use Disorder (AUD) shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 18 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Alcohol Use Disorder (AUD) is led by Yale University with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 31 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Alcohol Use Disorder (AUD)?
PlainTrial tracks 31 US clinical trials for Alcohol Use Disorder (AUD), of which 22 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Alcohol Use Disorder (AUD)?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.