Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Alcohol Use Disorder (AUD): early-phase trial registry
22 of 31 indexed Alcohol Use Disorder (AUD) trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #495 of 28,707 conditions by registered trial count.
31 US clinical trials · 22 currently recruiting · #495 of 28,707 conditions by registered trial count
Alcohol Use Disorder (AUD): 31 US clinical trials tracked, 22 recruiting.
Alcohol Use Disorder (AUD) is the subject of 31 registered US clinical trials on ClinicalTrials.gov, 22 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 18 in Phase 1-2 (earlier-stage). The most active sponsor is Yale University, running 4 of these trials.
Enrollment posture brief
Registry condition alcohol-use-disorder-aud
OPEN 22 | RECR 71% | LATE 0 | EARLY 18 | RANK #495 | SPON 4
Volume-matched condition peers
Nearest open-share peer: Acute Myeloid Leukemia, in Relapse (71% recruiting · 17 trials)
Alcohol Use Disorder (AUD) lists 22 open slots (71% of 31 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Alcohol Use Disorder (AUD) on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Alcohol Use Disorder (AUD) is recruiting above its size-band peers.
22 of 31 indexed trials (71%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Alcohol Use Disorder (AUD) trials is spread across many organizations.
Yale University accounts for 4 of 31 trials (12.9%). 21 distinct sponsors appear on at least one study for this condition label.
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Typical Alcohol Use Disorder (AUD) enrolment sits around 86 participants.
Median target enrolment is 86 among the 31 trials that report a genuine target (sentinel values excluded). 16 of those (51.6%) plan for fewer than 100 participants.
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Alcohol Use Disorder (AUD) research is mostly interventional.
28 interventional and 3 observational studies make up this index (90.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
31 total, page 1 of 1
Combining a Smartphone App With Medications to Manage Heavy Drinking
VA Office of Research and Development
NCT06303778
Pharmaceutically-Enhanced Reinforcement for Reduced Alcohol and Smoking
Washington State University
NCT05181891
The Zonisamide and Reinforcement for Reducing Alcohol Use (ZARRA) Study
Washington State University
NCT05134857
The Oklahoma Parent-Child Assistance Program
University of Oklahoma
NCT05534568
Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics
Yale University
NCT06624137
Alcohol and the Social Brain: An Alcohol-Administration Hyperscanning Study Employing a Within-Subject Design
University of Illinois at Urbana-Champaign
NCT07125534
Alpha-1 Blockade for Alcohol Use Disorder (AUD)
Brown University
NCT04135846
Suvorexant for Alcohol Use Disorder (AUD): Neural Mechanisms
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NCT06484075
Probenecid Administration for Alcohol Craving and Consumption
Brown University
NCT07118618
MPFC Theta Burst Stimulation as a Treatment Tool for Alcohol Use Disorder: Effects on Drinking and Incentive Salience
Medical University of South Carolina
NCT04998916
Recovery Through Inhibitory Learning, Self-Efficacy Building, Problem Solving, and Community Building
University of Rhode Island
NCT07217795
Suvorexant for Treatment of AUD and PTSD
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
NCT06679062
The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)
Yale University
NCT06070649
Influence of Mavoglurant on Alcohol Craving and Drinking in Heavy Drinkers
Yale University
NCT06136195
iTBS for Alcohol Use Disorder
Nicholas Balderston, PhD
NCT06696365
Psilocybin With Psychological Support (Psi-PS) for Military Veterans and First Responders With Co-occurring PTSD & Alcohol Use Disorder (AUD)
Nathan Brashares Sackett
NCT06853912
Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 3 Semaglutide
Yale University
NCT07040592
Developing a Music Listening mHealth Intervention for Stress Reduction in Early Recovery
Washington State University
NCT07052318
Renewed Recovery: a Pilot Test of a Web-Based Mindfulness-Based Relapse Prevention Continuing Care Intervention for Alcohol Use Disorder
University of Georgia
NCT06987526
Diclofenac Dose Response Study
University of Maryland, Baltimore
NCT06636227
Study of Tirzepatide for Recovery and Alcohol Use Management
Brigham and Women's Hospital
NCT06727331
Effect of Sublingual Formulation of Dexmedetomidine Hydrochloride (HCl) (BXCL501) - Outpatient Study
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
NCT06335407
Comprehensive Process Model of AA-related Behavior Change
University of New Mexi
NCT04618653
A Study to Investigate the Safety and Efficacy of TMP-301 Compared to Placebo in Adult Patients With Alcohol Use Disorder
Tempero Bio
NCT06648655
RECLAIM STUDY: A Phase 2 Evaluating the Efficacy and Safety of Pemvidutide in the Treatment of Alcohol Use Disorder (AUD) in Subjects With Obesity or Overweight
Altimmune
NCT06987513
Ibudilast for Treating Alcohol Use Disorder
University of Pennsylvania
NCT05414240
Alcohol Telemedicine Consultation in Primary Care (ATC)
Kaiser Permanente
NCT05252221
Michigan SPARC Trial
Kaiser Permanente
NCT04861792
A Randomized, Double-blind Placebo-Controlled Pharmacogenetic Study of Topiramate in European-American Heavy Drinkers
University of Pennsylvania
NCT02371889
Brain Inflammation and Function in Alcoholism
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NCT02233868
Brain Network Modulation and Alcohol Use
Virginia Polytechnic Institute and State University
NCT04828577
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 6 |
| Phase 2 | 12 |
Top Sponsors
Named interventions
Most-linked intervention names on Alcohol Use Disorder (AUD) records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Alcohol Use Disorder (AUD) trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Alcohol Use Disorder (AUD) page
31 registered trials, 22 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 22 Alcohol Use Disorder (AUD) trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Yale University sponsors the most Alcohol Use Disorder (AUD) trials on record, review their full trial history before evaluating a specific study. See Yale University's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Alcohol Use Disorder (AUD) condition card totals 31 registered trials; most-linked intervention Placebo; top US site state Connecticut. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.