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NCT03537586 · ClinicalTrials.gov registry record · NA
A Single Center Diagnostic, Cross-sectional Study of Coronary Microvascular Dysfunction
A NA study of Myocardial Ischemia and Ischemic Heart Disease, sponsored by NYU Langone Health.
- Active
- Registry status
- NA
- Development phase
- 206
- Enrollment target
- 1
- Study location
NCT03537586: Active NA study of Myocardial Ischemia and Ischemic Heart Disease, sponsored by NYU Langone Health.
NCT03537586 is a NA study of Myocardial Ischemia and Ischemic Heart Disease that is active but no longer recruiting, run by NYU Langone Health. The registered enrollment target is 206 participants, below the 2,131-participant average among 29 other Myocardial Ischemia trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03537586, a NA study of Myocardial Ischemia and Ischemic Heart Disease, is active but no longer recruiting, sponsored by NYU Langone Health.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 206 participants
- Enrollment target
- 1
- Study location
Study Summary
Among patients with stable ischemic heart disease who are referred for coronary angiography, a substantial proportion have non-obstructive coronary artery disease (CAD). Ischemia based on symptoms or stress testing may be due to coronary microvascular dysfunction in up to 40% of these patients. However, the mechanisms and optimal treatment of coronary microvascular dysfunction are unknown. Aberrant platelet activity and inflammation have been hypothesized as mechanisms of microvascular dysfunction. Investigators plan to evaluate association between platelet activity, inflammation, and coronary microvascular dysfunction in stable women referred for coronary angiography, and to identify non-invasive correlates of coronary microvascular dysfunction in these patients.
Conditions Studied
Interventions
- DRUG Heparin
- DRUG Bivalirudin
- DRUG Adenosine
- DEVICE Pressure-Temperature Sensor Guidewire
- DEVICE Guiding Catheter
Study Locations (1)
New York
- New York University School of Medicine - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 206 participants |
| Start Date | 2018-06-29 |
| Est. Completion | 2026-06-30 |
| Phase | NA |
What the registry record for NCT03537586 still lists
NCT03537586 is an interventional study that assigns participants to a tested intervention. The registered 206 participants enrollment target is mid-sized for trials with a published cap, below the 2,131-participant average among 29 other Myocardial Ischemia trials with a reported enrollment target (90% lower).
The record links to 3 conditions, with Myocardial Ischemia appearing as the primary indexed condition, and to 5 interventions - of which Heparin is the first listed.
NCT03537586 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT03537586 about?
NCT03537586 is a clinical study titled "A Single Center Diagnostic, Cross-sectional Study of Coronary Microvascular Dysfunction". Among patients with stable ischemic heart disease who are referred for coronary angiography, a substantial proportion have non-obstructive coronary artery disease (CAD). Ischemia based on symptoms or stress testing may be due to coronary microvascular dysfunction in up to 40% of these patients. Howe...
What is the current status of trial NCT03537586?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 206 participants. The study started on 2018-06-29. Estimated completion is 2026-06-30.
What conditions does trial NCT03537586 study?
This clinical trial studies the following conditions: Myocardial Ischemia, Ischemic Heart Disease, Coronary Microvascular Disease.
What interventions are being tested in trial NCT03537586?
The interventions under investigation include: Heparin (DRUG), Bivalirudin (DRUG), Adenosine (DRUG), Pressure-Temperature Sensor Guidewire (DEVICE), Guiding Catheter (DEVICE).
Who is sponsoring clinical trial NCT03537586?
This trial is sponsored by NYU Langone Health, which has 1,164 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03537586 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Myocardial Ischemia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03537586's enrollment target sits among peer trials
206 18th of 29 higher than 12 of 29 other Myocardial Ischemia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Myocardial Ischemia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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