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NCT04237688 · ClinicalTrials.gov registry record
ECG Methods for the Prompt Identification of Coronary Events
A clinical trial of Myocardial Infarction and Acute Coronary Syndrome, sponsored by University of Pittsburgh.
- Completed
- Registry status
- 6,000
- Enrollment target
- 1
- Study location
NCT04237688: Completed study of Myocardial Infarction and Acute Coronary Syndrome, sponsored by University of Pittsburgh.
NCT04237688 is a study of Myocardial Infarction and Acute Coronary Syndrome that has completed, run by University of Pittsburgh. The registered enrollment target is 6,000 participants, above the 4,588-participant average among 64 other Myocardial Infarction trials with a reported enrollment target (31% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04237688, a study of Myocardial Infarction and Acute Coronary Syndrome, has completed, sponsored by University of Pittsburgh.
- COMPLETED
- Registry status
- 6,000 participants
- Enrollment target
- 1
- Study location
Study Summary
There is a clear need to develop improved tools to stratify risk in patients who seek emergency care for chest pain, one of the most common and potentially deadliest conditions encountered in acute care settings. The ECG has been the mainstay of initial evaluation of chest pain patients, yet is currently only diagnostic for a small subset of patients with ST-elevation myocardial infarction. Prior studies have identified candidate markers of ECG characteristics and preliminary algorithms that can identify patients with non-ST elevation myocardial infarction as well as those with very low risk of coronary artery disease. This study will enroll a cohort of consecutive chest pain patients needed to confirm the accuracy of these ECG markers and determine their maximal clinical utility as part of a risk stratification tool. With these improved tools, emergency providers (physicians, nurses, and paramedics) will be able to streamline the care provided to these patients beyond the costly and time-consuming overnight observation for serial cardiac enzymes and provocative testing.
Primary Outcome
The presence of symptoms of ischemia (i.e. diffuse discomfort in the chest, upper extremity, jaw, or epigastric area for more than 20 minutes) and at least one of the following criteria: (1) subsequent development of labile, ischemic ECG changes (e.g., ST changes, T inversion) during hospitalization, (2) elevation of cardiac troponin (i.e., \> 99th percentile) during hospital stay, (3) coronary angiography demonstrating greater than 70% stenosis, with or without treatment, and/or (4) functional
Conditions Studied
Study Locations (1)
Pennsylvania
- University of Pittsburgh Medical Center - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 6,000 participants |
| Start Date | 2013-05-01 |
| Est. Completion | 2023-12-31 |
What the finished NCT04237688 record still lists
NCT04237688 is an observational study that tracks outcomes without assigning an intervention. Its 6,000 participants enrollment target places it among the larger protocols in the corpus, above the 4,588-participant average among 64 other Myocardial Infarction trials with a reported enrollment target (31% higher).
The record links to 4 conditions, with Myocardial Infarction appearing as the primary indexed condition, and to 0 interventions.
NCT04237688 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT04237688 about?
NCT04237688 is a clinical study titled "ECG Methods for the Prompt Identification of Coronary Events". There is a clear need to develop improved tools to stratify risk in patients who seek emergency care for chest pain, one of the most common and potentially deadliest conditions encountered in acute care settings. The ECG has been the mainstay of initial evaluation of chest pain patients, yet is curr...
What is the current status of trial NCT04237688?
This trial is currently completed. The enrollment target is 6,000 participants. The study started on 2013-05-01. Estimated completion is 2023-12-31.
What conditions does trial NCT04237688 study?
This clinical trial studies the following conditions: Myocardial Infarction, Acute Coronary Syndrome, Myocardial Ischemia, Chest Pain.
Who is sponsoring clinical trial NCT04237688?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04237688 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT04237688's enrollment target sits among peer trials
6,000 10th of 64 higher than 55 of 64 other Myocardial Infarction trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Myocardial Infarction trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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