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NCT05762952 · ClinicalTrials.gov registry record · Phase 1
Effect of Dapagliflozin on Microvascular Function in Women With Symptoms of Coronary Artery Disease
A Phase 1 study of Myocardial Ischemia, sponsored by University of Virginia.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT05762952 is a Phase 1 study of Myocardial Ischemia that is actively recruiting participants, run by University of Virginia. The registered enrollment target is 40 participants, below the 2,136-participant average among 29 other Myocardial Ischemia trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05762952, a Phase 1 study of Myocardial Ischemia, is actively recruiting participants, sponsored by University of Virginia.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to test the effects of a drug (in the drug class called sodium-glucose cotransporter 2 inhibitors) in women who have symptoms of ischemic heart disease. The main questions the study aims to answer are: Does blood flow in the heart improve with study drug? Participants will be randomly assigned to a 12-week course of the study drug, dapagliflozin 10mg, or placebo. Blood flow in the heart will be assessed using stress cardiac magnetic resonance imaging at baseline and 12 weeks. The researchers will compare the results from the two groups.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Dapagliflozin 10mg Tab
Study Locations (1)
Virginia
- University of Virginia - Charlottesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2023-06-06 |
| Est. Completion | 2026-03-31 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05762952
The ClinicalTrials.gov registry entry for NCT05762952 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,136-participant average among 29 other Myocardial Ischemia trials with a reported enrollment target (98% lower). The listed sponsor is University of Virginia, which has 449 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Myocardial Ischemia appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT05762952 reports 1 study location spanning 1 distinct geographic area - top geographies include Virginia.
Frequently Asked Questions
What is clinical trial NCT05762952 about?
NCT05762952 is a clinical study titled "Effect of Dapagliflozin on Microvascular Function in Women With Symptoms of Coronary Artery Disease". The goal of this clinical trial is to test the effects of a drug (in the drug class called sodium-glucose cotransporter 2 inhibitors) in women who have symptoms of ischemic heart disease. The main questions the study aims to answer are: Does blood flow in the heart improve with study drug? Partici...
What is the current status of trial NCT05762952?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2023-06-06. Estimated completion is 2026-03-31.
What conditions does trial NCT05762952 study?
This clinical trial studies the following conditions: Myocardial Ischemia.
What interventions are being tested in trial NCT05762952?
The interventions under investigation include: Placebo (DRUG), Dapagliflozin 10mg Tab (DRUG).
Who is sponsoring clinical trial NCT05762952?
This trial is sponsored by University of Virginia, which has 449 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05762952 being conducted?
This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.