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NCT07052695 · ClinicalTrials.gov registry record · Phase 1

Mosunetuzumab for CLL MRD Clearance

A Phase 1 study of Lymphoma and Leukemia, sponsored by Inhye Ahn.

Recruiting
Registry status
Phase 1
Development phase
40
Enrollment target
2
Study locations

NCT07052695 is a Phase 1 study of Lymphoma and Leukemia that is actively recruiting participants, run by Inhye Ahn. The registered enrollment target is 40 participants, below the 484-participant average among 299 other Lymphoma trials with a reported enrollment target (92% lower). The trial reports 2 study locations across 1 state.

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The verdict

NCT07052695, a Phase 1 study of Lymphoma and Leukemia, is actively recruiting participants, sponsored by Inhye Ahn.

RECRUITING
Registry status
Phase 1
Development phase
40 participants
Enrollment target
2
Study locations

Study Summary

The goal of this study is to test mosunetuzumab given alone or in combination with a Bruton tyrosine kinase inhibitor (BTKi, such as ibrutinib, acalabrutinib, zanubrutinib, or pirtobrutinib) in participants with CLL (chronic lymphocytic leukemia) or small lymphocytic lymphoma (SLL). The names of the study drugs in this research study are: * Mosunetuzumab * BTK inhibitor: Ibrutinib, acalabrutinib, zanubrutinib, or pirtobrutinib

Interventions

  • DRUG Zanubrutinib
  • DRUG Mosunetuzumab
  • DRUG Pirtobrutinib
  • DRUG Acalabrutinib
  • DRUG Ibrutinib

Study Locations (2)

Massachusetts

  • Brigham & Women's Hospital - Boston
  • Dana-Farber Cancer Institute - Boston

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2025-11-24
Est. Completion 2032-12-31
Phase Phase 1

Sponsor

Inhye Ahn

2 total trials

What the Registry Record Tells You About NCT07052695

The ClinicalTrials.gov registry entry for NCT07052695 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 484-participant average among 299 other Lymphoma trials with a reported enrollment target (92% lower). The listed sponsor is Inhye Ahn, which has 2 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Lymphoma appearing as the primary indexed condition, and to 5 interventions - of which Zanubrutinib is the first listed.

NCT07052695 reports 2 study locations spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT07052695 about?

NCT07052695 is a clinical study titled "Mosunetuzumab for CLL MRD Clearance". The goal of this study is to test mosunetuzumab given alone or in combination with a Bruton tyrosine kinase inhibitor (BTKi, such as ibrutinib, acalabrutinib, zanubrutinib, or pirtobrutinib) in participants with CLL (chronic lymphocytic leukemia) or small lymphocytic lymphoma (SLL). The names of th...

What is the current status of trial NCT07052695?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2025-11-24. Estimated completion is 2032-12-31.

What conditions does trial NCT07052695 study?

This clinical trial studies the following conditions: Lymphoma, Leukemia, Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma.

What interventions are being tested in trial NCT07052695?

The interventions under investigation include: Zanubrutinib (DRUG), Mosunetuzumab (DRUG), Pirtobrutinib (DRUG), Acalabrutinib (DRUG), Ibrutinib (DRUG).

Who is sponsoring clinical trial NCT07052695?

This trial is sponsored by Inhye Ahn, which has 2 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07052695 being conducted?

This trial has 2 study locations across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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