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NCT00352924 · ClinicalTrials.gov registry record
Agriculture Health Study
A clinical trial of Prostate Cancer and Multiple Myeloma, sponsored by National Cancer Institute (NCI).
- Active
- Registry status
- 89,655
- Enrollment target
- 1
- Study location
NCT00352924 is a study of Prostate Cancer and Multiple Myeloma that is active but no longer recruiting, run by National Cancer Institute (NCI). The registered enrollment target is 89,655 participants, above the 486-participant average among 735 other Prostate Cancer trials with a reported enrollment target (18348% higher). The trial reports 1 study location across 1 state.
The verdict
NCT00352924, a study of Prostate Cancer and Multiple Myeloma, is active but no longer recruiting, sponsored by National Cancer Institute (NCI).
- ACTIVE NOT RECRUITING
- Registry status
- 89,655 participants
- Enrollment target
- 1
- Study location
Study Summary
The "Agricultural Health Study" (AHS) is a collaborative effort between the National Cancer Institute and the National Institute of Environmental Health Sciences. The U.S. Environmental Protection Agency and the National Institute for Occupational Safety and Health are providing support for a limited exposure assessment effort. Initial data collection on a prospective cohort of 89,658 study subjects has been completed as of December 1997. Participants completed questionnaires that included items on pesticides used, other agricultural exposures, and work practices that modify exposure as well as on other activities that may affect either exposure or disease risks (e.g., diet, exercise, alcohol consumption, medical conditions, family history of cancer, other occupations and smoking history). Phase II of the study (1998-2003) updated information on occupational exposures, diet, work practices and medical history by means of a computer assisted telephone interview. We also collected buccal cells on sample of 34,000 study participants to assess the effect of inheritable polymorphisms and the interaction of environment and genomic predisposition. The stimulus for this prospective investigation comes from the growing evidence that, despite a low mortality overall, farmers experience an excess of several cancers. These excesses have been observed in retrospective epidemiological studies among agricultural workers in several countries. Excess cancers are observed for the lymphatic and hematopoietic system, connective tissue, skin, brain, prostate, stomach and lips. Several of these tumors (brain, NHL, multiple myeloma, and prostate) are also increasing in the general population in many of these countries. This suggests a common set of exposures may explain the high rates in farmers and rising rates in the general population. Farmers, their families, and other pest control workers may have contact with a variety of potentially hazardous substances including pesticides, sol
Conditions Studied
Study Locations (1)
North Carolina
- Research Triangle Institute - Research Triangle Park
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 89,655 participants |
| Start Date | 1993-04-30 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00352924
The ClinicalTrials.gov registry entry for NCT00352924 describes a study currently listed as active not recruiting, categorized as an unspecified phase. The registered enrollment target is 89,655 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 486-participant average among 735 other Prostate Cancer trials with a reported enrollment target (18348% higher). The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.
The record links to 4 conditions, with Prostate Cancer appearing as the primary indexed condition, and to 0 interventions.
NCT00352924 reports 1 study location spanning 1 distinct geographic area - top geographies include North Carolina.
Frequently Asked Questions
What is clinical trial NCT00352924 about?
NCT00352924 is a clinical study titled "Agriculture Health Study". The "Agricultural Health Study" (AHS) is a collaborative effort between the National Cancer Institute and the National Institute of Environmental Health Sciences. The U.S. Environmental Protection Agency and the National Institute for Occupational Safety and Health are providing support for a limite...
What is the current status of trial NCT00352924?
This trial is currently active not recruiting. The enrollment target is 89,655 participants. The study started on 1993-04-30.
What conditions does trial NCT00352924 study?
This clinical trial studies the following conditions: Prostate Cancer, Multiple Myeloma, Lymphoma, Pesticide Exposures.
Who is sponsoring clinical trial NCT00352924?
This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00352924 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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