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Lung Cancer: early-phase trial registry
146 of 430 indexed Lung Cancer trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #12 of 28,707 conditions by registered trial count.
430 US clinical trials · 146 currently recruiting · #12 of 28,707 conditions by registered trial count
Lung Cancer: 430 US clinical trials tracked, 146 recruiting.
Lung Cancer is the subject of 430 registered US clinical trials on ClinicalTrials.gov, 146 of them currently open to new participants. 23 are in Phase 3-4 (later-stage) and 181 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 36 of these trials.
Enrollment posture brief
Registry condition lung-cancer
OPEN 146 | RECR 34% | LATE 23 | EARLY 181 | RANK #12 | SPON 36
Volume-matched condition peers
Nearest open-share peer: Solid Tumors (34% recruiting · 127 trials)
Lung Cancer lists 146 open slots (34% of 430 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Lung Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Lung Cancer is recruiting below its size-band peers.
146 of 430 indexed trials (34%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Lung Cancer trials is spread across many organizations.
Memorial Sloan Kettering Cancer Center accounts for 36 of 430 trials (8.4%). 179 distinct sponsors appear on at least one study for this condition label.
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Typical Lung Cancer enrolment sits around 89 participants.
Median target enrolment is 89 among the 410 trials that report a genuine target (sentinel values excluded). 212 of those (51.7%) plan for fewer than 100 participants.
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Lung Cancer research is mostly interventional.
321 interventional and 109 observational studies make up this index (74.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
430 total, page 8 of 9
Stereotactic Body Radiation Therapy in Stage II/III Non Small Cell Lung Cancer
Ronald McGarry
NCT01657617
Functional Imaging in Lung SBRT
University of Michigan Rogel Cancer Center
NCT03121300
Improving Management of Breathlessness in Patients With Lung Cancer
Massachusetts General Hospital
NCT01937637
Vaccine Therapy in Treating Patients With Stage I, Stage II, or Stage III Non-small Cell Lung Cancer
Edward Hirschowitz
NCT00103116
A Phase I Study of iPS Cell Generation From Patients With COPD
Mayo Clinic
NCT01860898
Proactive Psychiatry Consultation for Patients With Cancer and Severe Mental Illness
Massachusetts General Hospital
NCT02594696
Combination Chemotherapy and Radiation Therapy Followed By Surgery in Treating Patients With Stage IIB or Stage IIIA Non-Small Cell Lung Cancer
Medstar Health Research Institute
NCT00006469
Chemotherapy, Tirapazamine, and Radiation Therapy in Treating Patients With Non-Small Cell Lung Cancer
California Cancer Consortium
NCT00033410
Arsenic Trioxide in Treating Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
The University of Texas Medical Branch, Galveston
NCT00075426
Pilot Study to Evaluate Optical Frequency Domain Imaging for Diagnosis of Central Airway Disease
Massachusetts General Hospital
NCT01396603
Vinorelbine and XR9576 to Treat Cancer
National Cancer Institute (NCI)
NCT00001944
Radiofrequency Ablation in Treating Patients With Refractory or Advanced Lung Cancer
Jonsson Comprehensive Cancer Center
NCT00024076
G1T38, a CDK 4/6 Inhibitor, in Combination With Osimertinib in EGFR-Mutant Non-Small Cell Lung Cancer
G1 Therapeutics
NCT03455829
Feasibility of an Evidence-based Walking Program in Cancer Pts 60+ During Chemotherapy
UNC Lineberger Comprehensive Cancer Center
NCT01789983
Paclitaxel and Cisplatin Plus Radiation Therapy Followed by Filgrastim in Treating Patients With Recurrent Head and Neck Cancer or Lung Cancer
Fox Chase Cancer Center
NCT00021333
Growth Factor Levels in the Blood of Patients Undergoing Radiation Therapy for Epithelial Cancer
Vanderbilt-Ingram Cancer Center
NCT00897793
Megestrol in Treating Patients Who Are Undergoing Radiation Therapy for Lung Cancer
Wake Forest University Health Sciences
NCT00031785
A Study to Evaluate Pegsitacianine, an Intraoperative Fluorescence Imaging Agent for the Detection of Lung Malignancies
OncoNano Medicine
NCT05048082
A Phase 1/2 Trial of Trametinib and Erlotinib in Patients With EGFR-Mutant Lung Adenocarcinomas and Acquired Resistance to Erlotinib
Memorial Sloan Kettering Cancer Center
NCT03076164
Vaccine Therapy, Interleukin-2, and Sargramostim in Treating Patients With Advanced Tumors
Georgetown University
NCT00003125
Pain Management Smartphone Application for Patients With Stage III-IV Head and Neck Cancer Undergoing Radiation Therapy
Vanderbilt-Ingram Cancer Center
NCT02324881
Clinical Trial of Metastasis Inhibitor NP-G2-044 in Patients With Advanced or Metastatic Treatment-Refractory Solid Tumor Malignancies
Novita Pharmaceuticals
NCT03199586
BAY 43-9006 in Previously Untreated Patients With Non-Small Cell Lung Cancer (NSCLC)
M.D. Anderson Cancer Center
NCT00533585
Trial of Ruxolitinib and Erlotinib in Patients With EGFR-mutant Lung Adenocarcinoma With Acquired Resistance to Erlotinib
Memorial Sloan Kettering Cancer Center
NCT02155465
Bintrafusp Alfa Program Rollover Study
EMD Serono Research & Development Institute
NCT05061823
Lapatinib and Cetuximab in Patients With Solid Tumors
Georgetown University
NCT01184482
Combination Chemotherapy Plus Fluoxetine in Treating Patients With Advanced or Recurrent Non-Small Cell Lung Cancer
Alliance for Clinical Trials in Oncology
NCT00005850
Project HEALS (Helping and Empowering pAtients for Living a Life Smoke-free
H. Lee Moffitt Cancer Center and Research Institute
NCT05362318
Radiation Therapy Plus Topotecan in Treating Patients With Non-small Cell Lung Cancer
National Cancer Institute (NCI)
NCT00002537
Phase II Trial of Sunitinib in BAC or Never-Smokers With Any Lung Adenocarcinoma
Swedish Medical Center
NCT00430261
Vaccine Therapy in Treating Patients With Stage I, Stage II, or Stage IIIA Non-small Cell Lung Cancer or With Stage I or Stage II Mesothelioma
Roswell Park Cancer Institute
NCT00003974
CPT-11/Cisplatin and Celecoxib With Radiation Therapy for Patients With Unresectable Non-Small Cell Lung Cancer (NSCLC)
M.D. Anderson Cancer Center
NCT00346801
Evaluation of Appeal and Impact of E-Cigarettes Among Chronic Smokers With Smoking-Related Cancers
Dartmouth-Hitchcock Medical Center
NCT02648178
Risk Stratification for Patients With Hospital-diagnosed Advanced Lung Cancer
UNC Lineberger Comprehensive Cancer Center
NCT05722847
A Study Comparing Oral Picoplatin With Intravenous Picoplatin in Subjects With Solid Tumors
Poniard Pharmaceuticals
NCT00465725
Gemcitabine and Carboplatin Followed By Docetaxel in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
Case Comprehensive Cancer Center
NCT00074204
Gold Sodium Thiomalate in Treating Patients With Advanced Non-Small Cell Lung Cancer
Mayo Clinic
NCT00575393
Phase I Vorinostat Concurrent With Stereotactic Radiosurgery (SRS) in Brain Metastases From Non-Small Cell Lung Cancer
Stanford University
NCT00946673
Photodynamic Therapy Using HPPH in Treating Patients With Stage 0 Non-Small Cell Lung Cancer
Roswell Park Cancer Institute
NCT00526461
Erlotinib in Treating Patients With Advanced Non-Small Cell Lung Cancer
Vanderbilt-Ingram Cancer Center
NCT00416650
Sorafenib, Pemetrexed, and Cisplatin in Treating Patients With Advanced Solid Tumors
Masonic Cancer Center, University of Minnesota
NCT00703638
Bryostatin 1 Plus Paclitaxel in Treating Patients With Stage IIIB, Stage IV, or Recurrent Non-small Cell Lung Cancer
University of Chicago
NCT00005849
Topotecan in Combination With Pemetrexed in Patients With Advanced Malignancies
SCRI Development Innovations
NCT00315861
Combination Chemotherapy in Treating Patients With Extensive-Stage Small Cell Lung Cancer
Wake Forest University Health Sciences
NCT00025272
Study to Assess Food Effect on Pharmacokinetics of Entinostat in Subjects With Breast Cancer or Non-Small Cell Lung Cancer
Syndax Pharmaceuticals
NCT01594398
Using an End-of-life Conversation Game to Engage Patients With Cancer in Advance Care Planning
Milton S. Hershey Medical Center
NCT06028152
Sunitinib in Never-Smokers With Lung Adenocarcinoma
Dana-Farber Cancer Institute
NCT01829217
A Phase I/II Study of Bexarotene in Combination With ZD1839 (IRESSA®) in the Treatment of Non-Small Cell Lung Cancer
Stanford University
NCT00238628
Investigating Radiation-Induced Injury to Airways and Pulmonary Vasculature in Lung Stereotactic Ablative Body Radiotherapy (SAbR)
University of Texas Southwestern Medical Center
NCT05459311
Stereotactic Body Radiation for Consolidation After Standard Chemoradiation for Stage 3 Lung Cancer
Dr Thomas DiPetrillo
NCT01656460
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 85 |
| Phase 2 | 96 |
| Phase 3 | 22 |
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Lung Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Lung Cancer trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Lung Cancer page
430 registered trials, 146 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 146 Lung Cancer trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Memorial Sloan Kettering Cancer Center sponsors the most Lung Cancer trials on record, review their full trial history before evaluating a specific study. See Memorial Sloan Kettering Cancer Center's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Lung Cancer condition card totals 430 registered trials; most-linked intervention paclitaxel; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.