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NCT05459311 · ClinicalTrials.gov registry record
Investigating Radiation-Induced Injury to Airways and Pulmonary Vasculature in Lung Stereotactic Ablative Body Radiotherapy (SAbR)
A clinical trial of Lung Cancer and Thoracic Cancer, sponsored by University of Texas Southwestern Medical Center.
- Completed
- Registry status
- 12
- Enrollment target
- 1
- Study location
NCT05459311 is a study of Lung Cancer and Thoracic Cancer that has completed, run by University of Texas Southwestern Medical Center. The registered enrollment target is 12 participants, below the 936-participant average among 409 other Lung Cancer trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05459311, a study of Lung Cancer and Thoracic Cancer, has completed, sponsored by University of Texas Southwestern Medical Center.
- COMPLETED
- Registry status
- 12 participants
- Enrollment target
- 1
- Study location
Study Summary
We will conduct a prospective clinical study involving up to 40 non-Small Cell Lung Cancer (nSCLC) patients to determine dose thresholds for central and peripheral BSS elements. All imaging will be performed under motion control (e.g., with or without abdominal compression) defined as breathing with a resultant motion ≤5mm by fluoroscopy. In this study, a high-resolution breath-hold CT scan (BHCT) will be acquired from each patient immediately before or after the 4DCT scan. A follow-up high resolution BHCT (also under motion control) will be acquired from each patient 8-12 months post-SabR, and BSS elements will be segmented in LungPointRT. A radiation oncologist will compare the pre- and post-SabR contours to determine segmental collapse.
Conditions Studied
Study Locations (1)
Texas
- UT Southwestern Cancer Center - Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2017-10-03 |
| Est. Completion | 2023-09-25 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05459311
The ClinicalTrials.gov registry entry for NCT05459311 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 936-participant average among 409 other Lung Cancer trials with a reported enrollment target (99% lower). The listed sponsor is University of Texas Southwestern Medical Center, which has 837 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Lung Cancer appearing as the primary indexed condition, and to 0 interventions.
NCT05459311 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.
Frequently Asked Questions
What is clinical trial NCT05459311 about?
NCT05459311 is a clinical study titled "Investigating Radiation-Induced Injury to Airways and Pulmonary Vasculature in Lung Stereotactic Ablative Body Radiotherapy (SAbR)". We will conduct a prospective clinical study involving up to 40 non-Small Cell Lung Cancer (nSCLC) patients to determine dose thresholds for central and peripheral BSS elements. All imaging will be performed under motion control (e.g., with or without abdominal compression) defined as breathing with...
What is the current status of trial NCT05459311?
This trial is currently completed. The enrollment target is 12 participants. The study started on 2017-10-03. Estimated completion is 2023-09-25.
What conditions does trial NCT05459311 study?
This clinical trial studies the following conditions: Lung Cancer, Thoracic Cancer.
Who is sponsoring clinical trial NCT05459311?
This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05459311 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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