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NCT00025272 · ClinicalTrials.gov registry record · Phase 2

Combination Chemotherapy in Treating Patients With Extensive-Stage Small Cell Lung Cancer

A Phase 2 study of Lung Cancer, sponsored by Wake Forest University Health Sciences.

Completed
Registry status
Phase 2
Development phase
14
Enrollment target
5
Study locations

NCT00025272: Completed Phase 2 study of Lung Cancer, sponsored by Wake Forest University Health Sciences.

NCT00025272 is a Phase 2 study of Lung Cancer that has completed, run by Wake Forest University Health Sciences. The registered enrollment target is 14 participants, below the 936-participant average among 409 other Lung Cancer trials with a reported enrollment target (99% lower). The trial reports 5 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00025272, a Phase 2 study of Lung Cancer, has completed, sponsored by Wake Forest University Health Sciences.

COMPLETED
Registry status
Phase 2
Development phase
14 participants
Enrollment target
5
Study locations

Study Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug and giving them in different ways may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combining topotecan, carboplatin, and etoposide in treating patients who have extensive-stage small cell lung cancer.

Conditions Studied

Interventions

  • DRUG carboplatin
  • DRUG etoposide
  • RADIATION radiation therapy
  • DRUG topotecan hydrochloride

Study Locations (5)

North Carolina

  • Southeastern Medical Oncology Center - Goldsboro
  • Comprehensive Cancer Center at Wake Forest University - Winston-Salem

South Carolina

  • CCOP - Greenville - Greenville
  • CCOP - Upstate Carolina - Spartanburg

Virginia

  • MBCCOP - Massey Cancer Center - Richmond

Trial Details

FieldValue
Enrollment Target 14 participants
Start Date 2001-11-01
Est. Completion 2005-01-18
Phase Phase 2
Wake Forest University Health Sciences

1,140 total trials

What the finished NCT00025272 record still lists

NCT00025272 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 14 participants, a relatively small participant target, below the 936-participant average among 409 other Lung Cancer trials with a reported enrollment target (99% lower).

The record links to 1 condition, with Lung Cancer appearing as the primary indexed condition, and to 4 interventions - of which carboplatin is the first listed.

NCT00025272 lists 5 locations in 3 states (North Carolina, South Carolina, Virginia).

Frequently Asked Questions

What is clinical trial NCT00025272 about?

NCT00025272 is a clinical study titled "Combination Chemotherapy in Treating Patients With Extensive-Stage Small Cell Lung Cancer". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug and giving them in different ways may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combining topotecan, carboplatin, a...

What is the current status of trial NCT00025272?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 14 participants. The study started on 2001-11-01. Estimated completion is 2005-01-18.

What conditions does trial NCT00025272 study?

This clinical trial studies the following conditions: Lung Cancer.

What interventions are being tested in trial NCT00025272?

The interventions under investigation include: carboplatin (DRUG), etoposide (DRUG), radiation therapy (RADIATION), topotecan hydrochloride (DRUG).

Who is sponsoring clinical trial NCT00025272?

This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00025272 being conducted?

This trial has 5 study locations across North Carolina, South Carolina, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Lung Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00025272's enrollment target sits among peer trials

14 380th of 409 higher than 28 of 409 other Lung Cancer trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Lung Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00025272, the US trial registry maintained by the National Library of Medicine. NCT00025272 (small enrollment · multi site footprint · completed) retrieved and formatted by PlainTrial, see methodology.