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NCT00003125 · ClinicalTrials.gov registry record · Phase 2

Vaccine Therapy, Interleukin-2, and Sargramostim in Treating Patients With Advanced Tumors

A Phase 2 study of Breast Cancer and Lung Cancer, sponsored by Georgetown University.

Completed
Registry status
Phase 2
Development phase
24
Enrollment target
2
Study locations

NCT00003125 is a Phase 2 study of Breast Cancer and Lung Cancer that has completed, run by Georgetown University. The registered enrollment target is 24 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (99% lower). The trial reports 2 study locations across 2 states.

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The verdict

NCT00003125, a Phase 2 study of Breast Cancer and Lung Cancer, has completed, sponsored by Georgetown University.

COMPLETED
Registry status
Phase 2
Development phase
24 participants
Enrollment target
2
Study locations

Study Summary

RATIONALE: Vaccines may make the body build an immune response to kill tumor cells. Colony-stimulating factors such as sargramostim may increase the number of immune cells. Interleukin-2 may stimulate a person's white blood cells to kill cancer cells. Combining vaccine therapy, sargramostim, and interleukin-2 may kill more cancer cells. PURPOSE: Randomized phase II trial to study the effectiveness of vaccine therapy, sargramostim, and interleukin-2 in treating patients who have advanced tumors.

Interventions

  • BIOLOGICAL aldesleukin
  • BIOLOGICAL sargramostim
  • BIOLOGICAL ALVAC-CEA vaccine
  • BIOLOGICAL vaccinia-CEA vaccine

Study Locations (2)

District of Columbia

  • Lombardi Cancer Center, Georgetown University - Washington D.C.

Maryland

  • National Naval Medical Center - Bethesda

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 1998-01
Est. Completion 2004-11
Phase Phase 2

Sponsor

Georgetown University

227 total trials

What the Registry Record Tells You About NCT00003125

The ClinicalTrials.gov registry entry for NCT00003125 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (99% lower). The listed sponsor is Georgetown University, which has 227 total studies on file at ClinicalTrials.gov.

The record links to 6 conditions, with Breast Cancer appearing as the primary indexed condition, and to 4 interventions - of which aldesleukin is the first listed.

NCT00003125 reports 2 study locations spanning 2 distinct geographic areas - top geographies include District of Columbia, Maryland.

Frequently Asked Questions

What is clinical trial NCT00003125 about?

NCT00003125 is a clinical study titled "Vaccine Therapy, Interleukin-2, and Sargramostim in Treating Patients With Advanced Tumors". RATIONALE: Vaccines may make the body build an immune response to kill tumor cells. Colony-stimulating factors such as sargramostim may increase the number of immune cells. Interleukin-2 may stimulate a person's white blood cells to kill cancer cells. Combining vaccine therapy, sargramostim, and int...

What is the current status of trial NCT00003125?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 24 participants. The study started on 1998-01. Estimated completion is 2004-11.

What conditions does trial NCT00003125 study?

This clinical trial studies the following conditions: Breast Cancer, Lung Cancer, Pancreatic Cancer, Gastric Cancer, Esophageal Cancer.

What interventions are being tested in trial NCT00003125?

The interventions under investigation include: aldesleukin (BIOLOGICAL), sargramostim (BIOLOGICAL), ALVAC-CEA vaccine (BIOLOGICAL), vaccinia-CEA vaccine (BIOLOGICAL).

Who is sponsoring clinical trial NCT00003125?

This trial is sponsored by Georgetown University, which has 227 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00003125 being conducted?

This trial has 2 study locations across District of Columbia, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.