Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00703638 · ClinicalTrials.gov registry record · Phase 1

Sorafenib, Pemetrexed, and Cisplatin in Treating Patients With Advanced Solid Tumors

A Phase 1 study of Breast Cancer and Prostate Cancer, sponsored by Masonic Cancer Center, University of Minnesota.

Completed
Registry status
Phase 1
Development phase
16
Enrollment target
1
Study location

NCT00703638 is a Phase 1 study of Breast Cancer and Prostate Cancer that has completed, run by Masonic Cancer Center, University of Minnesota. The registered enrollment target is 16 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00703638, a Phase 1 study of Breast Cancer and Prostate Cancer, has completed, sponsored by Masonic Cancer Center, University of Minnesota.

COMPLETED
Registry status
Phase 1
Development phase
16 participants
Enrollment target
1
Study location

Study Summary

RATIONALE: Sorafenib and pemetrexed may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Sorafenib may also stop the growth of tumor cells by blocking blood flow to the tumor. Drugs used in chemotherapy, such as cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving sorafenib together with pemetrexed and cisplatin may kill more tumor cells. PURPOSE: This phase I trial is studying the side effects and best dose of sorafenib when given together with pemetrexed and cisplatin in treating patients with advanced solid tumors.

Interventions

  • DRUG cisplatin
  • DRUG sorafenib
  • DRUG pemetrexed disodium

Study Locations (1)

Minnesota

  • Masonic Cancer Center, University of Minnesota - Minneapolis

Trial Details

FieldValue
Enrollment Target 16 participants
Start Date 2008-05
Est. Completion 2010-11
Phase Phase 1

What the Registry Record Tells You About NCT00703638

The ClinicalTrials.gov registry entry for NCT00703638 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 16 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (99% lower). The listed sponsor is Masonic Cancer Center, University of Minnesota, which has 249 total studies on file at ClinicalTrials.gov.

The record links to 8 conditions, with Breast Cancer appearing as the primary indexed condition, and to 3 interventions - of which cisplatin is the first listed.

NCT00703638 reports 1 study location spanning 1 distinct geographic area - top geographies include Minnesota.

Frequently Asked Questions

What is clinical trial NCT00703638 about?

NCT00703638 is a clinical study titled "Sorafenib, Pemetrexed, and Cisplatin in Treating Patients With Advanced Solid Tumors". RATIONALE: Sorafenib and pemetrexed may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Sorafenib may also stop the growth of tumor cells by blocking blood flow to the tumor. Drugs used in chemotherapy, such as cisplatin, work in different ways to stop the grow...

What is the current status of trial NCT00703638?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 16 participants. The study started on 2008-05. Estimated completion is 2010-11.

What conditions does trial NCT00703638 study?

This clinical trial studies the following conditions: Breast Cancer, Prostate Cancer, Lung Cancer, Colorectal Cancer, Pancreatic Cancer.

What interventions are being tested in trial NCT00703638?

The interventions under investigation include: cisplatin (DRUG), sorafenib (DRUG), pemetrexed disodium (DRUG).

Who is sponsoring clinical trial NCT00703638?

This trial is sponsored by Masonic Cancer Center, University of Minnesota, which has 249 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00703638 being conducted?

This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Breast Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.