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NCT02155465 · ClinicalTrials.gov registry record · Phase 1

Trial of Ruxolitinib and Erlotinib in Patients With EGFR-mutant Lung Adenocarcinoma With Acquired Resistance to Erlotinib

A Phase 1 study of Lung Cancer, sponsored by Memorial Sloan Kettering Cancer Center.

Completed
Registry status
Phase 1
Development phase
22
Enrollment target
6
Study locations

NCT02155465: Completed Phase 1 study of Lung Cancer, sponsored by Memorial Sloan Kettering Cancer Center.

NCT02155465 is a Phase 1 study of Lung Cancer that has completed, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 22 participants, below the 936-participant average among 409 other Lung Cancer trials with a reported enrollment target (98% lower). The trial reports 6 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02155465, a Phase 1 study of Lung Cancer, has completed, sponsored by Memorial Sloan Kettering Cancer Center.

COMPLETED
Registry status
Phase 1
Development phase
22 participants
Enrollment target
6
Study locations

Study Summary

This is a phase 2 study. The goal of this study is to find out what effects, good and/or bad, taking erlotinib and ruxolitinib has on the patients and on lung cancer. Erlotinib and ruxolitinib are FDA approved for other indications, but the use of erlotinib and ruxolitinib together has not been studied before and is not FDA-approved.

Conditions Studied

Interventions

  • DRUG Ruxolitinib
  • DRUG Erlotinib

Study Locations (6)

New York

  • Memorial Sloan Kettering Cancer Center @ Suffolk - Commack
  • Memorial Sloan Kettering West Harrison - Harrison
  • Memorial Sloan Kettering Cancer Center - New York
  • Memorial Sloan Kettering at Mercy Medical Center - Rockville Centre
  • Memoral Sloan Kettering Cancer Center at Phelps - Sleepy Hollow

New Jersey

  • Memoral Sloan Kettering Cancer Center - Basking Ridge

Trial Details

FieldValue
Enrollment Target 22 participants
Start Date 2014-06
Est. Completion 2017-10
Phase Phase 1

Sponsor

Memorial Sloan Kettering Cancer Center

1,884 total trials

What the Registry Record Tells You About NCT02155465

The ClinicalTrials.gov registry entry for NCT02155465 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 22 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 936-participant average among 409 other Lung Cancer trials with a reported enrollment target (98% lower). The listed sponsor is Memorial Sloan Kettering Cancer Center, which has 1,884 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Lung Cancer appearing as the primary indexed condition, and to 2 interventions - of which Ruxolitinib is the first listed.

NCT02155465 reports 6 study locations spanning 2 distinct geographic areas - top geographies include New York, New Jersey.

Frequently Asked Questions

What is clinical trial NCT02155465 about?

NCT02155465 is a clinical study titled "Trial of Ruxolitinib and Erlotinib in Patients With EGFR-mutant Lung Adenocarcinoma With Acquired Resistance to Erlotinib". This is a phase 2 study. The goal of this study is to find out what effects, good and/or bad, taking erlotinib and ruxolitinib has on the patients and on lung cancer. Erlotinib and ruxolitinib are FDA approved for other indications, but the use of erlotinib and ruxolitinib together has not been stud...

What is the current status of trial NCT02155465?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 22 participants. The study started on 2014-06. Estimated completion is 2017-10.

What conditions does trial NCT02155465 study?

This clinical trial studies the following conditions: Lung Cancer.

What interventions are being tested in trial NCT02155465?

The interventions under investigation include: Ruxolitinib (DRUG), Erlotinib (DRUG).

Who is sponsoring clinical trial NCT02155465?

This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02155465 being conducted?

This trial has 6 study locations across New Jersey, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.