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A Study Comparing Oral Picoplatin With Intravenous Picoplatin in Subjects With Solid Tumors
NCT00465725 · View on ClinicalTrials.gov ↗
Study Summary
Picoplatin is a new platinum-based chemotherapy drug that has been studied in a variety of cancers. Phase 1 and 2 studies have demonstrated that picoplatin may be effective in patients whose cancer returns or does not improve after treatment with chemotherapy. In these studies, picoplatin was administered intravenously. A capsule containing picoplatin has been formulated. This study will investigate the activity of the oral capsule in humans. Participants with advanced solid tumors will be enrolled.
Conditions Studied
Interventions
- DRUG Picoplatin
Study Locations (3)
Georgia
- Georgia Cancer Specialists — Atlanta
Nevada
- Nevada Cancer Institute — Las Vegas
Washington
- Northwest Medical Specialties — Tacoma
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2007-04 |
| Est. Completion | 2009-07 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00465725
The ClinicalTrials.gov registry entry for NCT00465725 describes a study currently listed as completed. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 18 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Poniard Pharmaceuticals, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 9 conditions, with Breast Cancer appearing as the primary indexed condition, and to 1 intervention — of which Picoplatin is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT00465725 reports 3 study locations spanning 3 distinct geographic areas — top geographies include Georgia, Nevada, Washington. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT00465725 about?
NCT00465725 is a clinical study titled "A Study Comparing Oral Picoplatin With Intravenous Picoplatin in Subjects With Solid Tumors". Picoplatin is a new platinum-based chemotherapy drug that has been studied in a variety of cancers. Phase 1 and 2 studies have demonstrated that picoplatin may be effective in patients whose cancer returns or does not improve after treatment with chemotherapy. In these studies, picoplatin was admini...
What is the current status of trial NCT00465725?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 18 participants. The study started on 2007-04. Estimated completion is 2009-07.
What conditions does trial NCT00465725 study?
This clinical trial studies the following conditions: Breast Cancer, Prostate Cancer, Lung Cancer, Colorectal Cancer, Ovarian Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT00465725?
The interventions under investigation include: Picoplatin (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT00465725?
This trial is sponsored by Poniard Pharmaceuticals, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT00465725 being conducted?
This trial has 3 study locations across Georgia, Nevada, Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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