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NCT00946673 · ClinicalTrials.gov registry record · Phase 1

Phase I Vorinostat Concurrent With Stereotactic Radiosurgery (SRS) in Brain Metastases From Non-Small Cell Lung Cancer

A Phase 1 study of Lung Cancer and Carcinoma, Non-Small Cell Lung, sponsored by Stanford University.

Completed
Registry status
Phase 1
Development phase
17
Enrollment target
2
Study locations

NCT00946673 is a Phase 1 study of Lung Cancer and Carcinoma, Non-Small Cell Lung that has completed, run by Stanford University. The registered enrollment target is 17 participants, below the 936-participant average among 409 other Lung Cancer trials with a reported enrollment target (98% lower). The trial reports 2 study locations across 2 states.

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The verdict

NCT00946673, a Phase 1 study of Lung Cancer and Carcinoma, Non-Small Cell Lung, has completed, sponsored by Stanford University.

COMPLETED
Registry status
Phase 1
Development phase
17 participants
Enrollment target
2
Study locations

Study Summary

The purpose of this study is to determine the maximum tolerated dose (MTD) of vorinostat given concurrently with stereotactic radiosurgery (SRS) to treat non-small cell lung cancer (NSCLCA) brain metastases in patient with 1-4 lesions.

Interventions

  • DRUG Vorinostat
  • PROCEDURE Radiation Therapy

Study Locations (2)

California

  • Stanford University School of Medicine - Stanford

Florida

  • Moffitt Cancer Center - Tampa

Trial Details

FieldValue
Enrollment Target 17 participants
Start Date 2009-06
Est. Completion 2015-07
Phase Phase 1

Sponsor

Stanford University

1,744 total trials

What the Registry Record Tells You About NCT00946673

The ClinicalTrials.gov registry entry for NCT00946673 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 17 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 936-participant average among 409 other Lung Cancer trials with a reported enrollment target (98% lower). The listed sponsor is Stanford University, which has 1,744 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Lung Cancer appearing as the primary indexed condition, and to 2 interventions - of which Vorinostat is the first listed.

NCT00946673 reports 2 study locations spanning 2 distinct geographic areas - top geographies include California, Florida.

Frequently Asked Questions

What is clinical trial NCT00946673 about?

NCT00946673 is a clinical study titled "Phase I Vorinostat Concurrent With Stereotactic Radiosurgery (SRS) in Brain Metastases From Non-Small Cell Lung Cancer". The purpose of this study is to determine the maximum tolerated dose (MTD) of vorinostat given concurrently with stereotactic radiosurgery (SRS) to treat non-small cell lung cancer (NSCLCA) brain metastases in patient with 1-4 lesions.

What is the current status of trial NCT00946673?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 17 participants. The study started on 2009-06. Estimated completion is 2015-07.

What conditions does trial NCT00946673 study?

This clinical trial studies the following conditions: Lung Cancer, Carcinoma, Non-Small Cell Lung, Brain Cancer, Neoplasm Metastasis.

What interventions are being tested in trial NCT00946673?

The interventions under investigation include: Vorinostat (DRUG), Radiation Therapy (PROCEDURE).

Who is sponsoring clinical trial NCT00946673?

This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00946673 being conducted?

This trial has 2 study locations across California, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.