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ClinicalTrials.gov 146 recruiting now early-phase tilt #12 of 28,963 conditions

Lung Cancer: early-phase trial registry

146 of 430 indexed Lung Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #12 of 28,963 conditions by registered trial count.

430 US clinical trials · 146 currently recruiting · #12 of 28,963 conditions by registered trial count

Lung Cancer: 430 US clinical trials tracked, 146 recruiting.

Lung Cancer is the subject of 430 registered US clinical trials on ClinicalTrials.gov, 146 of them currently open to new participants. 23 are in Phase 3-4 (later-stage) and 181 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 36 of these trials.

Open enrollment, early-phase tilt

Lung Cancer has 430 registered US clinical trials, 146 of them open to new participants right now, about 34% of the total.

146
recruiting participants now
34%
of trials open to enrollment
23
in Phase 3-4 (later-stage)
36
top sponsor: Memorial Sloan Kettering Cancer Center

Corpus placement: #12 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.

Key findings

What ClinicalTrials.gov does not surface for Lung Cancer on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.

  1. Lung Cancer is recruiting below its size-band peers.

    146 of 430 indexed trials (34%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Lung Cancer trials is spread across many organizations.

    Memorial Sloan Kettering Cancer Center accounts for 36 of 430 trials (8.4%). 179 distinct sponsors appear on at least one study for this condition label.

  3. Typical Lung Cancer enrolment sits around 89 participants.

    Median target enrolment is 89 among the 410 trials that report a genuine target (sentinel values excluded). 212 of those (51.7%) plan for fewer than 100 participants.

  4. Lung Cancer research is mostly interventional.

    321 interventional and 109 observational studies make up this index (74.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 185Phase 296Phase 322Phase 41

Open and recent trials

430 total, page 6 of 9

COMPLETED 279 participants

A Retrospective Multicenter Review to Evaluate the Performance of the Ion Endoluminal System in Sampling Pulmonary Lesions

Intuitive Surgical

NCT05160571

COMPLETED 250 participants

Clinical Validation of InferRead Lung CT.AI

Infervision

NCT04119960

COMPLETED Phase 3 245 participants

Communicating Smoking Risks Through Graphic Warning Labels

University of Pennsylvania

NCT01782053

COMPLETED 235 participants

Gene Polymorphisms and Symptoms in Lung Cancer Patients

M.D. Anderson Cancer Center

NCT00504374

COMPLETED Phase 2 233 participants

A Study of Pembrolizumab Plus Epacadostat With Platinum-based Chemotherapy Versus Pembrolizumab Plus Platinum-based Chemotherapy Plus Placebo in Metastatic Non-Small Cell Lung Cancer (KEYNOTE-715-06/ECHO-306-06)

Incyte Corporation

NCT03322566

COMPLETED 218 participants

DNA Repair and Genetic Susceptibility to Lung Cancer

Memorial Sloan Kettering Cancer Center

NCT00611598

COMPLETED 216 participants

Quality of Life and Pain Outcomes Following Video-Assisted Thoracic Surgery (VATS) Anatomic Lung Resection Versus Thoracotomy and Anatomic Lung Resection

Memorial Sloan Kettering Cancer Center

NCT00598000

COMPLETED Phase 3 213 participants

Stereotactic Radiation Therapy With or Without Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases

Alliance for Clinical Trials in Oncology

NCT00377156

COMPLETED 204 participants

Protein and RNA Expression Patterns in Predicting Response to Treatment in Patients With Lung Cancer

Vanderbilt-Ingram Cancer Center

NCT00897650

COMPLETED 173 participants

Diagnostic Study for Lung Cancer Detection Test

Bioview

NCT01700452

COMPLETED Phase 2 162 participants

Study of Vandetanib Combined With Chemotherapy to Treat Advanced Non-small Cell Lung Cancer

PrECOG

NCT00687297

COMPLETED 161 participants

Metabolism of NNK Among African Americans

Masonic Cancer Center, University of Minnesota

NCT01158456

COMPLETED Phase 2 157 participants

Pemetrexed Disodium Plus Gemcitabine in Treating Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Alliance for Clinical Trials in Oncology

NCT00022646

COMPLETED Phase 2 152 participants

Iloprost in Preventing Lung Cancer in Patients at High Risk for This Disease

University of Colorado, Denver

NCT00084409

COMPLETED NA 150 participants

Patient-Centered Intervention to Reduce Cancer Patients' Financial Toxicity

Washington University School of Medicine

NCT04314284

COMPLETED NA 150 participants

All in One Study: A Prospective Trial of Electromagnetic Navigation for Biopsy of Pulmonary Nodules

Veran Medical Technologies

NCT03338049

COMPLETED 146 participants

S1013: Validation of Cancer Questionnaire for Skin Toxicities in Patients With Colorectal Cancer or Lung Cancer Receiving Cetuximab, Panitumumab, or Erlotinib Hydrochloride

SWOG Cancer Research Network

NCT01416688

COMPLETED Phase 2 140 participants

Carboplatin and Gemcitabine Combined With Celecoxib and/or Zileuton in Treating Patients With Advanced Non-Small Cell Lung Cancer

Alliance for Clinical Trials in Oncology

NCT00070486

COMPLETED NA 138 participants

Promoting Radon Testing Via Smartphone App: A Clinical Trial in a High Radon State

University of North Dakota

NCT04980521

COMPLETED NA 130 participants

Testing Radon Com Methods: Clinical Trial Smartphone App vs Print Brochures

University of North Dakota

NCT05319457

COMPLETED NA 125 participants

Routine Evaluation of the Social Determinants of Health in Oncology: User-centered Resource Coordination and Engagement

Dana-Farber Cancer Institute

NCT04879927

COMPLETED 121 participants

Prevalence+Significance of Paraneoplastic Autoantibodies in Many Cancers

Memorial Sloan Kettering Cancer Center

NCT00608452

COMPLETED NA 120 participants

Shared Decision Making in Rural Primary Care Lung Cancer Screening and Smoking Cessation

University of Colorado, Denver

NCT04897568

COMPLETED 119 participants

Mechanisms of Immunosurveillance for Lung Cancer

Washington University School of Medicine

NCT01710319

COMPLETED 112 participants

Biomarkers in the Nose, Throat, and Lung Tissue of Smokers and Non-Smokers

University of Colorado, Denver

NCT00897364

COMPLETED Phase 3 112 participants

ELUCIDATE: Enabling Lung Cancer Identification Using Folate Receptor Targeting

On Target Laboratories

NCT04241315

COMPLETED Phase 2 110 participants

Pemetrexed Disodium With or Without Sorafenib as Second-Line Therapy in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer

Alliance for Clinical Trials in Oncology

NCT00454194

COMPLETED Phase 2 109 participants

Docetaxel in Treating Patients With Solid Tumors

Alliance for Clinical Trials in Oncology

NCT00003565

COMPLETED Phase 3 108 participants

PROStep: A Feasibility Trial Using PROs and Step Data to Monitor Patients With Lung and GI Cancers

Abramson Cancer Center at Penn Medicine

NCT04616768

COMPLETED NA 107 participants

A Pilot Study of Geriatric Specific Interventions for Quality of Life in Elderly Patients With Cancer

Memorial Sloan Kettering Cancer Center

NCT00984321

COMPLETED NA 102 participants

Inpatient Smokers and LDCT Screening RCT

Boston University

NCT03276806

COMPLETED NA 100 participants

Interactive Voice Response System (IVRS) for Managing Symptoms of Patients Following Thoracic Surgery

M.D. Anderson Cancer Center

NCT00505024

COMPLETED Phase 2 98 participants

Radiation Therapy in Treating Patients With Stage I or Stage II Non-Small Cell Lung Cancer

Roswell Park Cancer Institute

NCT00843726

COMPLETED 98 participants

Immune Responses in Prostate, Lung, Melanoma and Breast Cancer Patients Following Stereotactic Body Radiotherapy (SBRT), Intensity Modulated Radiotherapy (IMRT) or Brachytherapy

Mayo Clinic

NCT01777802

COMPLETED Phase 2 94 participants

Radiation Therapy in Treating Patients With Stage I Non-Small Cell Lung Cancer

Radiation Therapy Oncology Group

NCT00960999

COMPLETED Phase 1 93 participants

Optimization of Smoking Cessation Strategies Concurrent With Treatment of Tobacco Related Malignancies

University of Kentucky

NCT02048917

COMPLETED Phase 2 89 participants

S0636: Erlotinib and Bevacizumab in Never-Smokers With Stage IIIB or Stage IV Primary Non-Small Cell Lung Cancer

SWOG Cancer Research Network

NCT00445848

COMPLETED Phase 2 88 participants

S9914: Combination Chemotherapy Plus Filgrastim in Untreated Extensive-Stage Small Cell Lung Cancer

SWOG Cancer Research Network

NCT00004137

COMPLETED 86 participants

Respiratory Tumor and Normal Tissue Motion

M.D. Anderson Cancer Center

NCT00415675

COMPLETED Phase 2 86 participants

Erlotinib, Paclitaxel, and Carboplatin in Treating Patients With Stage III, Stage IV, or Recurrent Non-Small Cell Lung Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT00287989

COMPLETED Phase 2 85 participants

S0720: Adjuvant Therapy Based on Gene Expression in Stage IA and IB Non-Small Cell Lung Cancer

SWOG Cancer Research Network

NCT00792701

COMPLETED Phase 1 84 participants

An Open-label, Phase I/IIa, Dose Escalating Study of 2B3-101 in Patients With Solid Tumors and Brain Metastases or Recurrent Malignant Glioma.

BBB-Therapeutics B.V.

NCT01386580

COMPLETED Phase 2 80 participants

Combination Chemotherapy in Treating Patients With Metastatic Ovarian Cancer or Non-small Cell Lung Cancer

University of California, San Francisco

NCT00003072

COMPLETED Phase 2 75 participants

PET Scan in Patients With Lung and Esophageal Cancers That May Be Removed by Surgery

Memorial Sloan Kettering Cancer Center

NCT00002930

COMPLETED 75 participants

Oncology Research Information Exchange Network (ORIEN) Lung Cancer Study

H. Lee Moffitt Cancer Center and Research Institute

NCT02803333

COMPLETED Phase 1 74 participants

Gefitinib and Everolimus in Treating Patients With Stage IIIB or Stage IV or Recurrent Non-Small Cell Lung Cancer

Memorial Sloan Kettering Cancer Center

NCT00096486

COMPLETED Phase 1 73 participants

Combination Chemotherapy and Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer

Alliance for Clinical Trials in Oncology

NCT00006012

COMPLETED Phase 2 71 participants

Chemotherapy and Radiation Therapy With or Without Panitumumab in Treating Patients With Stage IIIA Non-Small Cell Lung Cancer

Radiation Therapy Oncology Group

NCT00979212

COMPLETED 70 participants

Pharmacogenomic Study in Patients of Lung, Colorectal and Head/Neck Cancers Receiving Chemotherapy

University of Kansas Medical Center

NCT00442520

COMPLETED Phase 2 70 participants

Reproducibility of 18F Uptake by Solid Tumors Using PET Imaging Following Intravenous Administration of (18F) Injection

GE Healthcare

NCT00918281

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Phase Distribution

PhaseTrial count
Phase 1 85
Phase 2 96
Phase 3 22
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What is open for Lung Cancer right now

146 recruiting of 430 indexed (34% open).

Phase mix: 23 late (III/IV) vs 181 early (I/II) (early-phase heavy).

Top sponsor: Memorial Sloan Kettering Cancer Center (36 trials), 9 others listed. 50 shown below, recruiting first. #12 of 28,963 conditions by registered trial count.

How open-enrollment share is computed

Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.

Frequently Asked Questions

How many clinical trials are there for Lung Cancer?

PlainTrial tracks 430 US clinical trials for Lung Cancer, of which 146 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Lung Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.