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Lung Cancer: early-phase trial registry
146 of 430 indexed Lung Cancer trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #12 of 28,707 conditions by registered trial count.
430 US clinical trials · 146 currently recruiting · #12 of 28,707 conditions by registered trial count
Lung Cancer: 430 US clinical trials tracked, 146 recruiting.
Lung Cancer is the subject of 430 registered US clinical trials on ClinicalTrials.gov, 146 of them currently open to new participants. 23 are in Phase 3-4 (later-stage) and 181 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 36 of these trials.
Enrollment posture brief
Registry condition lung-cancer
OPEN 146 | RECR 34% | LATE 23 | EARLY 181 | RANK #12 | SPON 36
Volume-matched condition peers
Nearest open-share peer: Solid Tumors (34% recruiting · 127 trials)
Lung Cancer lists 146 open slots (34% of 430 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Lung Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Lung Cancer is recruiting below its size-band peers.
146 of 430 indexed trials (34%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Lung Cancer trials is spread across many organizations.
Memorial Sloan Kettering Cancer Center accounts for 36 of 430 trials (8.4%). 179 distinct sponsors appear on at least one study for this condition label.
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Typical Lung Cancer enrolment sits around 89 participants.
Median target enrolment is 89 among the 410 trials that report a genuine target (sentinel values excluded). 212 of those (51.7%) plan for fewer than 100 participants.
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Lung Cancer research is mostly interventional.
321 interventional and 109 observational studies make up this index (74.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
430 total, page 6 of 9
A Retrospective Multicenter Review to Evaluate the Performance of the Ion Endoluminal System in Sampling Pulmonary Lesions
Intuitive Surgical
NCT05160571
Clinical Validation of InferRead Lung CT.AI
Infervision
NCT04119960
Communicating Smoking Risks Through Graphic Warning Labels
University of Pennsylvania
NCT01782053
Gene Polymorphisms and Symptoms in Lung Cancer Patients
M.D. Anderson Cancer Center
NCT00504374
A Study of Pembrolizumab Plus Epacadostat With Platinum-based Chemotherapy Versus Pembrolizumab Plus Platinum-based Chemotherapy Plus Placebo in Metastatic Non-Small Cell Lung Cancer (KEYNOTE-715-06/ECHO-306-06)
Incyte Corporation
NCT03322566
DNA Repair and Genetic Susceptibility to Lung Cancer
Memorial Sloan Kettering Cancer Center
NCT00611598
Quality of Life and Pain Outcomes Following Video-Assisted Thoracic Surgery (VATS) Anatomic Lung Resection Versus Thoracotomy and Anatomic Lung Resection
Memorial Sloan Kettering Cancer Center
NCT00598000
Stereotactic Radiation Therapy With or Without Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases
Alliance for Clinical Trials in Oncology
NCT00377156
Protein and RNA Expression Patterns in Predicting Response to Treatment in Patients With Lung Cancer
Vanderbilt-Ingram Cancer Center
NCT00897650
Diagnostic Study for Lung Cancer Detection Test
Bioview
NCT01700452
Study of Vandetanib Combined With Chemotherapy to Treat Advanced Non-small Cell Lung Cancer
PrECOG
NCT00687297
Metabolism of NNK Among African Americans
Masonic Cancer Center, University of Minnesota
NCT01158456
Pemetrexed Disodium Plus Gemcitabine in Treating Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Alliance for Clinical Trials in Oncology
NCT00022646
Iloprost in Preventing Lung Cancer in Patients at High Risk for This Disease
University of Colorado, Denver
NCT00084409
Patient-Centered Intervention to Reduce Cancer Patients' Financial Toxicity
Washington University School of Medicine
NCT04314284
All in One Study: A Prospective Trial of Electromagnetic Navigation for Biopsy of Pulmonary Nodules
Veran Medical Technologies
NCT03338049
S1013: Validation of Cancer Questionnaire for Skin Toxicities in Patients With Colorectal Cancer or Lung Cancer Receiving Cetuximab, Panitumumab, or Erlotinib Hydrochloride
SWOG Cancer Research Network
NCT01416688
Carboplatin and Gemcitabine Combined With Celecoxib and/or Zileuton in Treating Patients With Advanced Non-Small Cell Lung Cancer
Alliance for Clinical Trials in Oncology
NCT00070486
Promoting Radon Testing Via Smartphone App: A Clinical Trial in a High Radon State
University of North Dakota
NCT04980521
Testing Radon Com Methods: Clinical Trial Smartphone App vs Print Brochures
University of North Dakota
NCT05319457
Routine Evaluation of the Social Determinants of Health in Oncology: User-centered Resource Coordination and Engagement
Dana-Farber Cancer Institute
NCT04879927
Prevalence+Significance of Paraneoplastic Autoantibodies in Many Cancers
Memorial Sloan Kettering Cancer Center
NCT00608452
Shared Decision Making in Rural Primary Care Lung Cancer Screening and Smoking Cessation
University of Colorado, Denver
NCT04897568
Mechanisms of Immunosurveillance for Lung Cancer
Washington University School of Medicine
NCT01710319
Biomarkers in the Nose, Throat, and Lung Tissue of Smokers and Non-Smokers
University of Colorado, Denver
NCT00897364
ELUCIDATE: Enabling Lung Cancer Identification Using Folate Receptor Targeting
On Target Laboratories
NCT04241315
Pemetrexed Disodium With or Without Sorafenib as Second-Line Therapy in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
Alliance for Clinical Trials in Oncology
NCT00454194
Docetaxel in Treating Patients With Solid Tumors
Alliance for Clinical Trials in Oncology
NCT00003565
PROStep: A Feasibility Trial Using PROs and Step Data to Monitor Patients With Lung and GI Cancers
Abramson Cancer Center at Penn Medicine
NCT04616768
A Pilot Study of Geriatric Specific Interventions for Quality of Life in Elderly Patients With Cancer
Memorial Sloan Kettering Cancer Center
NCT00984321
Inpatient Smokers and LDCT Screening RCT
Boston University
NCT03276806
Interactive Voice Response System (IVRS) for Managing Symptoms of Patients Following Thoracic Surgery
M.D. Anderson Cancer Center
NCT00505024
Radiation Therapy in Treating Patients With Stage I or Stage II Non-Small Cell Lung Cancer
Roswell Park Cancer Institute
NCT00843726
Immune Responses in Prostate, Lung, Melanoma and Breast Cancer Patients Following Stereotactic Body Radiotherapy (SBRT), Intensity Modulated Radiotherapy (IMRT) or Brachytherapy
Mayo Clinic
NCT01777802
Radiation Therapy in Treating Patients With Stage I Non-Small Cell Lung Cancer
Radiation Therapy Oncology Group
NCT00960999
Optimization of Smoking Cessation Strategies Concurrent With Treatment of Tobacco Related Malignancies
University of Kentucky
NCT02048917
S0636: Erlotinib and Bevacizumab in Never-Smokers With Stage IIIB or Stage IV Primary Non-Small Cell Lung Cancer
SWOG Cancer Research Network
NCT00445848
S9914: Combination Chemotherapy Plus Filgrastim in Untreated Extensive-Stage Small Cell Lung Cancer
SWOG Cancer Research Network
NCT00004137
Respiratory Tumor and Normal Tissue Motion
M.D. Anderson Cancer Center
NCT00415675
Erlotinib, Paclitaxel, and Carboplatin in Treating Patients With Stage III, Stage IV, or Recurrent Non-Small Cell Lung Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT00287989
S0720: Adjuvant Therapy Based on Gene Expression in Stage IA and IB Non-Small Cell Lung Cancer
SWOG Cancer Research Network
NCT00792701
An Open-label, Phase I/IIa, Dose Escalating Study of 2B3-101 in Patients With Solid Tumors and Brain Metastases or Recurrent Malignant Glioma.
BBB-Therapeutics B.V.
NCT01386580
Combination Chemotherapy in Treating Patients With Metastatic Ovarian Cancer or Non-small Cell Lung Cancer
University of California, San Francisco
NCT00003072
PET Scan in Patients With Lung and Esophageal Cancers That May Be Removed by Surgery
Memorial Sloan Kettering Cancer Center
NCT00002930
Oncology Research Information Exchange Network (ORIEN) Lung Cancer Study
H. Lee Moffitt Cancer Center and Research Institute
NCT02803333
Gefitinib and Everolimus in Treating Patients With Stage IIIB or Stage IV or Recurrent Non-Small Cell Lung Cancer
Memorial Sloan Kettering Cancer Center
NCT00096486
Combination Chemotherapy and Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer
Alliance for Clinical Trials in Oncology
NCT00006012
Chemotherapy and Radiation Therapy With or Without Panitumumab in Treating Patients With Stage IIIA Non-Small Cell Lung Cancer
Radiation Therapy Oncology Group
NCT00979212
Pharmacogenomic Study in Patients of Lung, Colorectal and Head/Neck Cancers Receiving Chemotherapy
University of Kansas Medical Center
NCT00442520
Reproducibility of 18F Uptake by Solid Tumors Using PET Imaging Following Intravenous Administration of (18F) Injection
GE Healthcare
NCT00918281
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 85 |
| Phase 2 | 96 |
| Phase 3 | 22 |
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Lung Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Lung Cancer trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Lung Cancer page
430 registered trials, 146 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 146 Lung Cancer trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Memorial Sloan Kettering Cancer Center sponsors the most Lung Cancer trials on record, review their full trial history before evaluating a specific study. See Memorial Sloan Kettering Cancer Center's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Lung Cancer condition card totals 430 registered trials; most-linked intervention paclitaxel; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.