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COMPLETED Phase 2

Radiation Therapy in Treating Patients With Stage I Non-Small Cell Lung Cancer

NCT00960999 · View on ClinicalTrials.gov ↗

Study Summary

RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Specialized radiation therapy that delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue. It is not yet known which regimen of stereotactic body radiation therapy is more effective in treating patients with non-small cell lung cancer. PURPOSE: This randomized phase II trial is studying the side effects of two radiation therapy regimens and to see how well they work in treating patients with stage I non-small cell lung cancer.

Conditions Studied

Interventions

  • RADIATION Single-fraction stereotactic body radiation therapy (SBRT)
  • RADIATION Multiple-fraction stereotactic body radiation therapy (SBRT)

Study Locations (20)

California

  • Auburn Radiation Oncology — Auburn
  • Alta Bates Summit Comprehensive Cancer Center — Berkeley
  • Radiation Oncology Centers - Cameron Park — Cameron Park
  • Mercy Cancer Center at Mercy San Juan Medical Center — Carmichael
  • UCSF Helen Diller Family Comprehensive Cancer Center — San Francisco

Illinois

  • Robert H. Lurie Comprehensive Cancer Center at Northwestern University — Chicago
  • Community Cancer Center — Normal
  • Advocate Lutheran General Cancer Care Center — Park Ridge
  • OSF St. Francis Medical Center — Peoria

Florida

  • Baptist Cancer Institute - Jacksonville — Jacksonville
  • M.D. Anderson Cancer Center at Orlando — Orlando

Indiana

  • Parkview Regional Cancer Center at Parkview Health — Fort Wayne
  • Memorial Hospital of South Bend — South Bend

Kentucky

  • Lucille P. Markey Cancer Center at University of Kentucky — Lexington
  • James Graham Brown Cancer Center at University of Louisville — Louisville

Michigan

  • Josephine Ford Cancer Center at Henry Ford Hospital — Detroit
  • Great Lakes Cancer Institute at McLaren Regional Medical Center — Flint

Missouri

  • CCOP - Kansas City — Kansas City
  • Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis — St Louis

Colorado

  • University of Colorado Cancer Center at UC Health Sciences Center — Aurora

Trial Details

FieldValue
Enrollment Target 94 participants
Start Date 2009-11
Est. Completion 2018-05-14
Phase Phase 2

Sponsor

Radiation Therapy Oncology Group

37 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00960999

The ClinicalTrials.gov registry entry for NCT00960999 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 94 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Radiation Therapy Oncology Group, which has 37 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Lung Cancer appearing as the primary indexed condition, and to 2 interventions — of which Single-fraction stereotactic body radiation therapy (SBRT) is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00960999 reports 20 study locations spanning 8 distinct geographic areas — top geographies include California, Illinois, Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00960999 about?

NCT00960999 is a clinical study titled "Radiation Therapy in Treating Patients With Stage I Non-Small Cell Lung Cancer". RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Specialized radiation therapy that delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue. It is not yet known which regimen of stereotactic body radiation ther...

What is the current status of trial NCT00960999?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 94 participants. The study started on 2009-11. Estimated completion is 2018-05-14.

What conditions does trial NCT00960999 study?

This clinical trial studies the following conditions: Lung Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00960999?

The interventions under investigation include: Single-fraction stereotactic body radiation therapy (SBRT) (RADIATION), Multiple-fraction stereotactic body radiation therapy (SBRT) (RADIATION). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00960999?

This trial is sponsored by Radiation Therapy Oncology Group, which has 37 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00960999 being conducted?

This trial has 20 study locations across California, Colorado, Florida, Illinois, Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial