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ClinicalTrials.gov 146 recruiting now early-phase tilt #12 of 28,963 conditions

Lung Cancer: early-phase trial registry

146 of 430 indexed Lung Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #12 of 28,963 conditions by registered trial count.

430 US clinical trials · 146 currently recruiting · #12 of 28,963 conditions by registered trial count

Lung Cancer: 430 US clinical trials tracked, 146 recruiting.

Lung Cancer is the subject of 430 registered US clinical trials on ClinicalTrials.gov, 146 of them currently open to new participants. 23 are in Phase 3-4 (later-stage) and 181 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 36 of these trials.

Open enrollment, early-phase tilt

Lung Cancer has 430 registered US clinical trials, 146 of them open to new participants right now, about 34% of the total.

146
recruiting participants now
34%
of trials open to enrollment
23
in Phase 3-4 (later-stage)
36
top sponsor: Memorial Sloan Kettering Cancer Center

Corpus placement: #12 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.

Key findings

What ClinicalTrials.gov does not surface for Lung Cancer on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.

  1. Lung Cancer is recruiting below its size-band peers.

    146 of 430 indexed trials (34%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Lung Cancer trials is spread across many organizations.

    Memorial Sloan Kettering Cancer Center accounts for 36 of 430 trials (8.4%). 179 distinct sponsors appear on at least one study for this condition label.

  3. Typical Lung Cancer enrolment sits around 89 participants.

    Median target enrolment is 89 among the 410 trials that report a genuine target (sentinel values excluded). 212 of those (51.7%) plan for fewer than 100 participants.

  4. Lung Cancer research is mostly interventional.

    321 interventional and 109 observational studies make up this index (74.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 185Phase 296Phase 322Phase 41

Open and recent trials

430 total, page 5 of 9

ACTIVE NOT RECRUITING NA 40 participants

Evaluation of Improved Onboard Patient Imaging

Varian, a Siemens Healthineers Company

NCT06187103

ACTIVE NOT RECRUITING NA 32 participants

Using an End-of-life Conversation Game to Engage Patients With Cancer in Advance Care Planning: Phase 2

Milton S. Hershey Medical Center

NCT06384417

ACTIVE NOT RECRUITING NA 30 participants

Real-Time Monitoring of Symptoms in Lung Cancer Patients Receiving Oral Targeted Therapies

University of Virginia

NCT05370469

ACTIVE NOT RECRUITING Phase 1 28 participants

Pembrolizumab (Immunotherapy Drug) in Combination With Guadecitabine and Mocetinostat (Epigenetic Drugs) for Patients With Advanced Lung Cancer.

Memorial Sloan Kettering Cancer Center

NCT03220477

ACTIVE NOT RECRUITING Phase 2 24 participants

The Neuroendocrine Effects of Pioglitazone in Patients With Cancer and Cachexia

Pennington Biomedical Research Center

NCT05919147

ACTIVE NOT RECRUITING Phase 1 22 participants

Oncolytic Adenovirus TILT-123 With Pembrolizumab as Treatment for Refractory Non-Small Cell Lung Cancer

TILT Biotherapeutics

NCT06125197

ACTIVE NOT RECRUITING Phase 1 21 participants

Ceritinib Plus Docetaxel in ALK-Negative, EGFR WT Advanced NSCLC

H. Lee Moffitt Cancer Center and Research Institute

NCT03611738

ACTIVE NOT RECRUITING Phase 2 21 participants

Study Assessing QBS72S For Treating Brain Metastases

Stanford University

NCT05305365

ACTIVE NOT RECRUITING NA 20 participants

Copper Cu 64 Anti-CEA Monoclonal Antibody M5A PET in Diagnosing Patients With CEA Positive Cancer

City of Hope Medical Center

NCT02293954

ACTIVE NOT RECRUITING Phase 2 19 participants

Afatinib With CT and RT for EGFR-Mutant NSCLC

Massachusetts General Hospital

NCT01553942

ACTIVE NOT RECRUITING Phase 1 18 participants

Adoptive Cell Therapy Using Cancer Specific CD8+ Tumor Infiltrating Lymphocytes in Adult Patients With Solid Tumors

AgonOx

NCT05902520

ACTIVE NOT RECRUITING Phase 2 18 participants

Osimertinib and Abemaciclib in EGFR Mutant Non-Small Cell Lung Cancer After Osimertinib Resistance

University of California, San Diego

NCT04545710

ACTIVE NOT RECRUITING NA 17 participants

Respiratory Motion-Corrected Cone-Beam CT and Intratreatment Gating Based on Electromagnetic Transponders to Reduce Target Position Uncertainty in Radiation Treatment of Lung Malignancies

Memorial Sloan Kettering Cancer Center

NCT02434809

ACTIVE NOT RECRUITING Phase 2 13 participants

Treating Early-stage Non-Small Cell Lung Cancer With Durvalumab and Radiation Therapy

Memorial Sloan Kettering Cancer Center

NCT04716946

ACTIVE NOT RECRUITING Phase 1 12 participants

Amivantamab With Tyrosine Kinase Inhibitors (TKI) for Advanced NSCLC With ALK, ROS1, or RET Alterations

University of Colorado, Denver

NCT05845671

ACTIVE NOT RECRUITING Phase 1 11 participants

A Study of the Combination of Osimertinib, Platinum and Etoposide for Patients With Metastatic EGFR Mutant Lung Cancers

Memorial Sloan Kettering Cancer Center

NCT03567642

ACTIVE NOT RECRUITING Phase 2 10 participants

An Open-Label Study to Enable Continued Treatment Access for Subjects Previously Enrolled in Studies of Ruxolitinib

Incyte Corporation

NCT02955940

ACTIVE NOT RECRUITING NA 7 participants

Oncology Episode Payment Model in Hawaii

University of Pennsylvania

NCT03523546

ACTIVE NOT RECRUITING Phase 1 6 participants

Safety & Efficacy of Consolidative Hypofractionated Radiation Therapy for Boosting Residual Lung Cancer With Durvalumab

University of Nebraska

NCT04748419

ACTIVE NOT RECRUITING NA 6 participants

A Study Comparing Mindfulness Apps to Decrease Anxiety in People With Lung Cancer

Memorial Sloan Kettering Cancer Center

NCT06008574

COMPLETED Phase 3 53,454 participants

National Lung Screening Trial (NLST) Screening

National Cancer Institute (NCI)

NCT00047385

COMPLETED 22,517 participants

Study on Prevalence and Impact of Brain Metastases on Survival in Lung Cancer by Line of Treatment

Daiichi Sankyo

NCT06557967

COMPLETED 2,472 participants

Cancer Prevention and Treatment Demonstration for Ethnic and Racial Minorities

M.D. Anderson Cancer Center

NCT00453661

COMPLETED 2,264 participants

S9925: Collecting and Storing Samples From Patients With Lung Cancer

SWOG Cancer Research Network

NCT00920010

COMPLETED 2,100 participants

An Analysis of Treatment Timelines for Lung Cancer Patients Across System Evolutions

St Elizabeth Healthcare

NCT03535766

COMPLETED Phase 3 1,708 participants

Comparison of Nicotine Inhaler and/or Bupropion in Helping People to Stop Smoking and Prevent the Recurrence of Smoking

Alliance for Clinical Trials in Oncology

NCT00033592

COMPLETED Phase 3 1,516 participants

Bevacizumab or Pemetrexed Disodium Alone or In Combination After Induction Therapy in Treating Patients With Advanced Non-Squamous Non-Small Cell Lung Cancer

ECOG-ACRIN Cancer Research Group

NCT01107626

COMPLETED 1,429 participants

PRospective REgistry of Advanced Stage CancER (PREFER) Patients to Assess Prevalence of Actionable Biomarkers and Driver Mutations to Address Disparities in Precision Medicine

Labcorp Corporation of America Holdings

NCT05697198

COMPLETED 1,189 participants

Pattern of Use and Safety/Effectiveness of Nivolumab in Routine Oncology Practice

Bristol-Myers Squibb

NCT02847728

COMPLETED NA 1,100 participants

Early Detection of Second Lung Cancer in Patients With Stage I Non-small Cell Lung Cancer

Eastern Cooperative Oncology Group

NCT00002667

COMPLETED 1,060 participants

Studying Tumor Tissue Samples From Patients With Early-Stage Non-Small Cell Lung Cancer

Alliance for Clinical Trials in Oncology

NCT01517971

COMPLETED 981 participants

S0424 - Carcinogens in Lung Tissue From Smokers (Closed to Entry as of 7/15/07) and Non-Smokers With Newly Diagnosed Stage I, Stage II, or Stage III Non-Small Cell Lung Cancer

SWOG Cancer Research Network

NCT00450281

COMPLETED NA 894 participants

Evaluation of a Patient 'nudge' on Engagement in Lung Cancer Screening

Kaiser Permanente

NCT06474611

COMPLETED 756 participants

Airway Epithelium Gene Expression in the Diagnosis of Lung Cancer: AEGIS CLIA

Allegro Diagnostics

NCT01309087

COMPLETED 691 participants

Transbronchial Biopsy Assisted by Robot Guidance in the Evaluation of Tumors of the Lung

Auris Health

NCT04182815

COMPLETED Phase 3 600 participants

Zoledronate in Treating Patients With Solid Tumors That Have Spread to the Bone

Novartis

NCT00003884

COMPLETED NA 531 participants

Early Detection of Lung Cancer in a High-Risk Population Defined by PFT, Biomarkers, and CT Scanning

Susanne Arnold

NCT00596310

COMPLETED 507 participants

Effect of Lung Cancer Diagnoses on Family Behaviors

National Human Genome Research Institute (NHGRI)

NCT01862770

COMPLETED NA 507 participants

Stepped Palliative Care Versus Early Integrated Palliative Care in Patients With Advanced Lung Cancer

Massachusetts General Hospital

NCT03337399

COMPLETED 489 participants

DECAMP-1: Diagnosis and Surveillance of Indeterminate Pulmonary Nodules

Boston University

NCT01785342

COMPLETED 445 participants

Pleural Catheters Versus Thoracoscopic Pleurodesis

M.D. Anderson Cancer Center

NCT01117740

COMPLETED 400 participants

African American Families and Lung Cancer Study

National Human Genome Research Institute (NHGRI)

NCT00487760

COMPLETED Phase 3 366 participants

Carboplatin, Paclitaxel, and Radiation Therapy in Treating Patients With Stage III Non-small Cell Lung Cancer That Cannot Be Removed During Surgery

Alliance for Clinical Trials in Oncology

NCT00003387

COMPLETED Phase 3 356 participants

Radiation Therapy in Preventing Central Nervous System (CNS) Metastases in Patients With Non-Small Cell Lung Cancer

Radiation Therapy Oncology Group

NCT00048997

COMPLETED Phase 3 354 participants

S9900: Surgery With or Without Combination Chemotherapy in Treating Patients With Non-small Cell Lung Cancer

SWOG Cancer Research Network

NCT00004011

COMPLETED 350 participants

Deuterated Phenanthrene Tetraol in Smokers Who Are at High Risk For Lung Cancer

University of Minnesota

NCT01673711

COMPLETED NA 325 participants

Collection of Patient-Reported Symptoms and Performance Status Via the Internet

Alliance for Clinical Trials in Oncology

NCT00417040

COMPLETED NA 317 participants

CareSTEPS: A Supportive Care Program for the Caregivers of Advanced Lung Cancer Patients

Baylor College of Medicine

NCT02414672

COMPLETED NA 303 participants

Positron Emission Tomography for Detecting Non-small Cell Lung Cancer

Alliance for Clinical Trials in Oncology

NCT00004138

COMPLETED NA 280 participants

Effects of Palliative Care on Quality of Life and Symptom Control in Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer That Cannot Be Removed by Surgery

City of Hope Medical Center

NCT00823732

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Phase Distribution

PhaseTrial count
Phase 1 85
Phase 2 96
Phase 3 22
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What is open for Lung Cancer right now

146 recruiting of 430 indexed (34% open).

Phase mix: 23 late (III/IV) vs 181 early (I/II) (early-phase heavy).

Top sponsor: Memorial Sloan Kettering Cancer Center (36 trials), 9 others listed. 50 shown below, recruiting first. #12 of 28,963 conditions by registered trial count.

How open-enrollment share is computed

Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.

Frequently Asked Questions

How many clinical trials are there for Lung Cancer?

PlainTrial tracks 430 US clinical trials for Lung Cancer, of which 146 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Lung Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.