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NCT00006012 · ClinicalTrials.gov registry record · Phase 1

Combination Chemotherapy and Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer

A Phase 1 study of Lung Cancer and Radiation Toxicity, sponsored by Alliance for Clinical Trials in Oncology.

Completed
Registry status
Phase 1
Development phase
73
Enrollment target
20
Study locations

NCT00006012 is a Phase 1 study of Lung Cancer and Radiation Toxicity that has completed, run by Alliance for Clinical Trials in Oncology. The registered enrollment target is 73 participants, below the 936-participant average among 409 other Lung Cancer trials with a reported enrollment target (92% lower). The trial reports 20 study locations across 3 states.

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The verdict

NCT00006012, a Phase 1 study of Lung Cancer and Radiation Toxicity, has completed, sponsored by Alliance for Clinical Trials in Oncology.

COMPLETED
Registry status
Phase 1
Development phase
73 participants
Enrollment target
20
Study locations

Study Summary

RATIONALE: Drugs used in chemotherapy work in different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining chemotherapy with radiation therapy may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy before, during, and after radiation therapy in treating patients who have limited-stage small cell lung cancer.

Interventions

  • DRUG cisplatin
  • DRUG paclitaxel
  • DRUG etoposide
  • BIOLOGICAL filgrastim
  • DRUG amifostine trihydrate

Study Locations (20)

Illinois

  • Rush-Copley Cancer Care Center - Aurora
  • St. Joseph Medical Center - Bloomington
  • Graham Hospital - Canton
  • Memorial Hospital - Carthage
  • Eureka Community Hospital - Eureka
  • Galesburg Clinic - Galesburg
  • Galesburg Cottage Hospital - Galesburg
  • InterCommunity Cancer Center of Western Illinois - Galesburg
  • Mason District Hospital - Havana
  • Hopedale Medical Complex - Hopedale
  • Joliet Oncology Hematology Associates, Limited - West - Joliet
  • Kewanee Hospital - Kewanee
  • McDonough District Hospital - Macomb
  • BroMenn Regional Medical Center - Normal
  • Community Cancer Center - Normal
  • Community Hospital of Ottawa - Ottawa
  • Oncology Hematology Associates of Central Illinois - Ottawa - Ottawa
  • Cancer Treatment Center at Pekin Hospital - Pekin

Arizona

  • CCOP - Mayo Clinic Scottsdale Oncology Program - Scottsdale

Florida

  • Mayo Clinic - Jacksonville - Jacksonville

Trial Details

FieldValue
Enrollment Target 73 participants
Start Date 2001-02
Est. Completion 2006-05
Phase Phase 1

What the Registry Record Tells You About NCT00006012

The ClinicalTrials.gov registry entry for NCT00006012 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 73 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 936-participant average among 409 other Lung Cancer trials with a reported enrollment target (92% lower). The listed sponsor is Alliance for Clinical Trials in Oncology, which has 446 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Lung Cancer appearing as the primary indexed condition, and to 5 interventions - of which cisplatin is the first listed.

NCT00006012 reports 20 study locations spanning 3 distinct geographic areas - top geographies include Illinois, Arizona, Florida.

Frequently Asked Questions

What is clinical trial NCT00006012 about?

NCT00006012 is a clinical study titled "Combination Chemotherapy and Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer". RATIONALE: Drugs used in chemotherapy work in different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining chemotherapy with radiation therapy may kill more cancer cells. PURPOSE: Phase II trial to study the...

What is the current status of trial NCT00006012?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 73 participants. The study started on 2001-02. Estimated completion is 2006-05.

What conditions does trial NCT00006012 study?

This clinical trial studies the following conditions: Lung Cancer, Radiation Toxicity, Drug/Agent Toxicity by Tissue/Organ.

What interventions are being tested in trial NCT00006012?

The interventions under investigation include: cisplatin (DRUG), paclitaxel (DRUG), etoposide (DRUG), filgrastim (BIOLOGICAL), amifostine trihydrate (DRUG).

Who is sponsoring clinical trial NCT00006012?

This trial is sponsored by Alliance for Clinical Trials in Oncology, which has 446 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00006012 being conducted?

This trial has 20 study locations across Arizona, Florida, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.