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NCT00415675 · ClinicalTrials.gov registry record

Respiratory Tumor and Normal Tissue Motion

A clinical trial of Lung Cancer and Abdominal Cancer, sponsored by M.D. Anderson Cancer Center.

Completed
Registry status
86
Enrollment target
1
Study location

NCT00415675: Completed study of Lung Cancer and Abdominal Cancer, sponsored by M.D. Anderson Cancer Center.

NCT00415675 is a study of Lung Cancer and Abdominal Cancer that has completed, run by M.D. Anderson Cancer Center. The registered enrollment target is 86 participants, below the 936-participant average among 409 other Lung Cancer trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00415675, a study of Lung Cancer and Abdominal Cancer, has completed, sponsored by M.D. Anderson Cancer Center.

COMPLETED
Registry status
86 participants
Enrollment target
1
Study location

Study Summary

Primary Objectives: * To collect accurate and reliable respiration-induced anatomic structure motion data using four-dimensional (4-D) imaging technology. * To analyze these data to study respiration-induced variations and patterns in variations of positions, shapes and volumes of tumors and normal anatomic structures in the thorax and abdomen over a breathing cycle, from one breathing cycle to the next, day-to-day and over the course of radiotherapy. * To assess dosimetric and potential clinical consequences of respiratory motion in the current practice of radiotherapy through preclinical treatment simulation (treatment planning) studies. * To quantify the potential consequences of explicitly accounting for respiration-induced motion on dose distributions and outcome (tumor control probabilities and normal tissue complication probabilities) through preclinical treatment simulation studies. Secondary Objectives: * To investigate the feasibility of using patient training to regulate patient breathing and improve the quality of images and to stratify patients for their eligibility for respiratory-correlated imaging and radiotherapy and for the implementation of various strategies for mitigation of respiratory-induced motion. * To assess the degree of correlation of the marker (or internal anatomic structure such as diaphragm) being tracked as surrogate of breathing with the motion of structures and the intra-fraction and inter-fraction reproducibility of such correlation. * To quantify the effects of radiation therapy on the patterns of respiratory-induced motion of structures through preclinical treatment simulation studies. * To compare various strategies for either accounting for or mitigating respiration-induced motion in the planning and delivery of radiation therapy.

Interventions

  • PROCEDURE Motion CT Scans

Study Locations (1)

Texas

  • UT MD Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 86 participants
Start Date 2004-11

Sponsor

M.D. Anderson Cancer Center

2,692 total trials

What the Registry Record Tells You About NCT00415675

The ClinicalTrials.gov registry entry for NCT00415675 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 86 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 936-participant average among 409 other Lung Cancer trials with a reported enrollment target (91% lower). The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Lung Cancer appearing as the primary indexed condition, and to 1 intervention - of which Motion CT Scans is the first listed.

NCT00415675 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT00415675 about?

NCT00415675 is a clinical study titled "Respiratory Tumor and Normal Tissue Motion". Primary Objectives: * To collect accurate and reliable respiration-induced anatomic structure motion data using four-dimensional (4-D) imaging technology. * To analyze these data to study respiration-induced variations and patterns in variations of positions, shapes and volumes of tumors and normal...

What is the current status of trial NCT00415675?

This trial is currently completed. The enrollment target is 86 participants. The study started on 2004-11.

What conditions does trial NCT00415675 study?

This clinical trial studies the following conditions: Lung Cancer, Abdominal Cancer.

What interventions are being tested in trial NCT00415675?

The interventions under investigation include: Motion CT Scans (PROCEDURE).

Who is sponsoring clinical trial NCT00415675?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00415675 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

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