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COMPLETED Phase 2

SWOG-9400 Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Patients With Previously Untreated Acute Lymphocytic Leukemia

NCT00002665 · View on ClinicalTrials.gov ↗

Study Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with bone marrow transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy with or without bone marrow transplantation in treating patients who have acute lymphocytic leukemia.

Interventions

  • DRUG cyclophosphamide
  • DRUG dexamethasone
  • DRUG cytarabine
  • DRUG asparaginase
  • DRUG daunorubicin hydrochloride

Study Locations (20)

California

  • Beckman Research Institute, City of Hope — Duarte
  • Veterans Affairs Medical Center - Long Beach — Long Beach
  • USC/Norris Comprehensive Cancer Center — Los Angeles
  • Jonsson Comprehensive Cancer Center, UCLA — Los Angeles
  • Veterans Affairs Outpatient Clinic - Martinez — Martinez
  • CCOP - Bay Area Tumor Institute — Oakland
  • University of California Davis Medical Center — Sacramento
  • CCOP - Santa Rosa Memorial Hospital — Santa Rosa
  • David Grant Medical Center — Travis Air Force Base

Arizona

  • CCOP - Greater Phoenix — Phoenix
  • Veterans Affairs Medical Center - Phoenix (Hayden) — Phoenix
  • Veterans Affairs Medical Center - Tucson — Tucson
  • Arizona Cancer Center — Tucson

Arkansas

  • University of Arkansas for Medical Sciences — Little Rock
  • Veterans Affairs Medical Center - Little Rock (McClellan) — Little Rock

Colorado

  • Veterans Affairs Medical Center - Denver — Denver
  • University of Colorado Cancer Center — Denver

Georgia

  • CCOP - Atlanta Regional — Atlanta
  • Dwight David Eisenhower Army Medical Center — Fort Gordon

Alabama

  • MBCCOP - University of South Alabama — Mobile

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 1995-07
Est. Completion 2003-12
Phase Phase 2

Sponsor

SWOG Cancer Research Network

212 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00002665

The ClinicalTrials.gov registry entry for NCT00002665 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is SWOG Cancer Research Network, which has 212 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 3 conditions, with Leukemia appearing as the primary indexed condition, and to 5 interventions — of which cyclophosphamide is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00002665 reports 20 study locations spanning 6 distinct geographic areas — top geographies include California, Arizona, Arkansas. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00002665 about?

NCT00002665 is a clinical study titled "SWOG-9400 Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Patients With Previously Untreated Acute Lymphocytic Leukemia". RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with bone marrow transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. PURPOSE: Phase II trial to stu...

What is the current status of trial NCT00002665?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 50 participants. The study started on 1995-07. Estimated completion is 2003-12.

What conditions does trial NCT00002665 study?

This clinical trial studies the following conditions: Leukemia, Thrombocytopenia, Neutropenia. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00002665?

The interventions under investigation include: cyclophosphamide (DRUG), dexamethasone (DRUG), cytarabine (DRUG), asparaginase (DRUG), daunorubicin hydrochloride (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00002665?

This trial is sponsored by SWOG Cancer Research Network, which has 212 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00002665 being conducted?

This trial has 20 study locations across Alabama, Arizona, Arkansas, California, Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial