Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
S0301 Cyclosporine, Daunorubicin, and Cytarabine in Treating Older Patients With Previously Untreated Acute Myeloid Leukemia
NCT00066794 · View on ClinicalTrials.gov ↗
Study Summary
RATIONALE: Drugs used in chemotherapy, such as cyclosporine, daunorubicin, and cytarabine, use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. PURPOSE: This phase II trial is studying how well giving cyclosporine together with daunorubicin and cytarabine works in treating older patients with untreated acute myeloid leukemia.
Conditions Studied
Interventions
- BIOLOGICAL filgrastim
- DRUG cytarabine
- DRUG cyclosporine
- BIOLOGICAL sargramostim
- DRUG daunorubicin hydrochloride
Study Locations (20)
Kansas
- Cancer Center of Kansas, PA - Chanute — Chanute
- Cancer Center of Kansas, PA - Dodge City — Dodge City
- Cancer Center of Kansas, PA - El Dorado — El Dorado
- Cancer Center of Kansas, PA - Kingman — Kingman
- Southwest Medical Center — Liberal
- Cancer Center of Kansas, PA - Newton — Newton
- Cancer Center of Kansas, PA - Parsons — Parsons
- Cancer Center of Kansas, PA - Pratt — Pratt
- Cancer Center of Kansas, PA - Salina — Salina
- Tammy Walker Cancer Center at Salina Regional Health Center — Salina
- Stormont-Vail Cancer Center — Topeka
- St. Francis Comprehensive Cancer Center — Topeka
- Cancer Center of Kansas, PA - Wellington — Wellington
California
- Chao Family Comprehensive Cancer Center at University of California Irvine Medical Center — Orange
- Mercy Regional Cancer Center at Mercy Medical Center — Redding
Illinois
- Saint Anthony's Hospital at Saint Anthony's Health Center — Alton
- Good Samaritan Regional Health Center — Mount Vernon
Alabama
- Mobile Infirmary Medical Center — Mobile
Arizona
- Arizona Cancer Center at University of Arizona Health Sciences Center — Tucson
Idaho
- St. Luke's Mountain States Tumor Institute - Boise — Boise
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 69 participants |
| Start Date | 2004-07 |
| Est. Completion | 2010-01 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00066794
The ClinicalTrials.gov registry entry for NCT00066794 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 69 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is SWOG Cancer Research Network, which has 212 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Leukemia appearing as the primary indexed condition, and to 5 interventions — of which filgrastim is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT00066794 reports 20 study locations spanning 6 distinct geographic areas — top geographies include Kansas, California, Illinois. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT00066794 about?
NCT00066794 is a clinical study titled "S0301 Cyclosporine, Daunorubicin, and Cytarabine in Treating Older Patients With Previously Untreated Acute Myeloid Leukemia". RATIONALE: Drugs used in chemotherapy, such as cyclosporine, daunorubicin, and cytarabine, use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. PURPOSE: This phase II trial is studying how well giving cyclosporin...
What is the current status of trial NCT00066794?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 69 participants. The study started on 2004-07. Estimated completion is 2010-01.
What conditions does trial NCT00066794 study?
This clinical trial studies the following conditions: Leukemia. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT00066794?
The interventions under investigation include: filgrastim (BIOLOGICAL), cytarabine (DRUG), cyclosporine (DRUG), sargramostim (BIOLOGICAL), daunorubicin hydrochloride (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT00066794?
This trial is sponsored by SWOG Cancer Research Network, which has 212 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT00066794 being conducted?
This trial has 20 study locations across Alabama, Arizona, California, Idaho, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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