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NCT01289457 · ClinicalTrials.gov registry record · Phase 1

Clofarabine, Idarubicin, and Cytarabine (CIA) Versus Fludarabine, Idarubicin, and Cytarabine (FLAI) in Acute Myelogenous Leukemia (AML) and High-Risk Myelodysplastic Syndrome

A Phase 1 study of Leukemia, sponsored by M.D. Anderson Cancer Center.

Completed
Registry status
Phase 1
Development phase
282
Enrollment target
1
Study location

NCT01289457 is a Phase 1 study of Leukemia that has completed, run by M.D. Anderson Cancer Center. The registered enrollment target is 282 participants, below the 486-participant average among 233 other Leukemia trials with a reported enrollment target (42% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT01289457, a Phase 1 study of Leukemia, has completed, sponsored by M.D. Anderson Cancer Center.

COMPLETED
Registry status
Phase 1
Development phase
282 participants
Enrollment target
1
Study location

Study Summary

The goal of this clinical research study is to learn if the combination of clofarabine, idarubicin, and cytarabine, or the combination of fludarabine, idarubicin, and cytarabine can help control Acute myeloid leukemia (AML) and Myelodysplastic syndromes (MDS). The safety of these study drug combinations will also be studied.

Conditions Studied

Interventions

  • DRUG Fludarabine
  • DRUG Cytarabine
  • DRUG Idarubicin
  • DRUG Clofarabine

Study Locations (1)

Texas

  • University of Texas MD Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 282 participants
Start Date 2011-02-02
Est. Completion 2017-06-28
Phase Phase 1

Sponsor

M.D. Anderson Cancer Center

2,692 total trials

What the Registry Record Tells You About NCT01289457

The ClinicalTrials.gov registry entry for NCT01289457 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 282 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 486-participant average among 233 other Leukemia trials with a reported enrollment target (42% lower). The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Leukemia appearing as the primary indexed condition, and to 4 interventions - of which Fludarabine is the first listed.

NCT01289457 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT01289457 about?

NCT01289457 is a clinical study titled "Clofarabine, Idarubicin, and Cytarabine (CIA) Versus Fludarabine, Idarubicin, and Cytarabine (FLAI) in Acute Myelogenous Leukemia (AML) and High-Risk Myelodysplastic Syndrome". The goal of this clinical research study is to learn if the combination of clofarabine, idarubicin, and cytarabine, or the combination of fludarabine, idarubicin, and cytarabine can help control Acute myeloid leukemia (AML) and Myelodysplastic syndromes (MDS). The safety of these study drug combinat...

What is the current status of trial NCT01289457?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 282 participants. The study started on 2011-02-02. Estimated completion is 2017-06-28.

What conditions does trial NCT01289457 study?

This clinical trial studies the following conditions: Leukemia.

What interventions are being tested in trial NCT01289457?

The interventions under investigation include: Fludarabine (DRUG), Cytarabine (DRUG), Idarubicin (DRUG), Clofarabine (DRUG).

Who is sponsoring clinical trial NCT01289457?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01289457 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.