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NCT01682226 · ClinicalTrials.gov registry record · Phase 2

Cord Blood With T-Cell Depleted Haplo-identical Peripheral Blood Stem Cell Transplantation for Hematological Malignancies

A Phase 2 study of Lymphoma and Leukemia, sponsored by Memorial Sloan Kettering Cancer Center.

Completed
Registry status
Phase 2
Development phase
84
Enrollment target
1
Study location

NCT01682226: Completed Phase 2 study of Lymphoma and Leukemia, sponsored by Memorial Sloan Kettering Cancer Center.

NCT01682226 is a Phase 2 study of Lymphoma and Leukemia that has completed, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 84 participants, below the 483-participant average among 299 other Lymphoma trials with a reported enrollment target (83% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01682226, a Phase 2 study of Lymphoma and Leukemia, has completed, sponsored by Memorial Sloan Kettering Cancer Center.

COMPLETED
Registry status
Phase 2
Development phase
84 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to find out whether the addition of blood stem cells from a close family member, when added to umbilical cord blood will make the transplant safer.

Primary Outcome

The primary endpoint is neutrophil recovery ie the speed \[median (range) days to recovery\] and success \[day 45 cumulative incidence percent\].

Interventions

  • DEVICE CliniMACS Fractionation system (Arm A)
  • DEVICE CliniMACS Fractionation system (Arm B)
  • BIOLOGICAL Haploidentical donor CD34+ cells

Study Locations (1)

New York

  • Memorial Sloan Kettering Cancer Center - New York

Trial Details

FieldValue
Enrollment Target 84 participants
Start Date 2012-09-05
Est. Completion 2021-01-08
Phase Phase 2
Memorial Sloan Kettering Cancer Center

1,884 total trials

What the finished NCT01682226 record still lists

NCT01682226 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 84 participants, a relatively small participant target, below the 483-participant average among 299 other Lymphoma trials with a reported enrollment target (83% lower).

The record links to 3 conditions, with Lymphoma appearing as the primary indexed condition, and to 3 interventions - of which CliniMACS Fractionation system (Arm A) is the first listed.

NCT01682226 reports a single indexed study location in New York.

Frequently Asked Questions

What is clinical trial NCT01682226 about?

NCT01682226 is a clinical study titled "Cord Blood With T-Cell Depleted Haplo-identical Peripheral Blood Stem Cell Transplantation for Hematological Malignancies". The purpose of this study is to find out whether the addition of blood stem cells from a close family member, when added to umbilical cord blood will make the transplant safer.

What is the current status of trial NCT01682226?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 84 participants. The study started on 2012-09-05. Estimated completion is 2021-01-08.

What conditions does trial NCT01682226 study?

This clinical trial studies the following conditions: Lymphoma, Leukemia, Myelodysplastic Syndrome.

What interventions are being tested in trial NCT01682226?

The interventions under investigation include: CliniMACS Fractionation system (Arm A) (DEVICE), CliniMACS Fractionation system (Arm B) (DEVICE), Haploidentical donor CD34+ cells (BIOLOGICAL).

Who is sponsoring clinical trial NCT01682226?

This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01682226 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Lymphoma

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT01682226's enrollment target sits among peer trials

84 99th of 299 higher than 200 of 299 other Lymphoma trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Lymphoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01682226, the US trial registry maintained by the National Library of Medicine. NCT01682226 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.