Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
HIV: early-phase trial registry
109 of 304 indexed HIV trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #27 of 28,707 conditions by registered trial count.
304 US clinical trials · 109 currently recruiting · #27 of 28,707 conditions by registered trial count
HIV: 304 US clinical trials tracked, 109 recruiting.
HIV is the subject of 304 registered US clinical trials on ClinicalTrials.gov, 109 of them currently open to new participants. 25 are in Phase 3-4 (later-stage) and 64 in Phase 1-2 (earlier-stage). The most active sponsor is National Institute of Allergy and Infectious Diseases (NIAID), running 24 of these trials.
Enrollment posture brief
Registry condition hiv
OPEN 109 | RECR 36% | LATE 25 | EARLY 64 | RANK #27 | SPON 24
Volume-matched condition peers
Nearest open-share peer: Acute Respiratory Failure (36% recruiting · 14 trials)
HIV lists 109 open slots (36% of 304 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for HIV on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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HIV recruits in line with its size-band peers.
109 of 304 indexed trials (35.9%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of HIV trials is spread across many organizations.
National Institute of Allergy and Infectious Diseases (NIAID) accounts for 24 of 304 trials (7.9%). 115 distinct sponsors appear on at least one study for this condition label.
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Typical HIV enrolment sits around 100 participants.
Median target enrolment is 100 among the 304 trials that report a genuine target (sentinel values excluded). 142 of those (46.7%) plan for fewer than 100 participants.
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HIV research is mostly interventional.
252 interventional and 52 observational studies make up this index (82.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
304 total, page 4 of 7
Evaluation of the HITSystem to Improve Early Infant Diagnosis Outcomes in Kenya
Sarah Kessler, PhD, MPH
NCT02072603
Reducing Sexual Risk Behaviors and Improving Health for People at a Sexually Transmitted Infection Clinic
The Miriam Hospital
NCT00947271
Behavioral Intervention Trial for HIV-infected Injection Drug Users
Centers for Disease Control and Prevention
NCT00146445
Training Community Members to Deliver HIV Prevention Programs to Urban Youth
Icahn School of Medicine at Mount Sinai
NCT00859144
HOPE Social Media Intervention for HIV Testing and Studying Social Networks
University of California, Irvine
NCT02944877
Study to Evaluate the Safety and Efficacy of E/C/F/TAF (Genvoya®) Versus E/C/F/TDF (Stribild®) in HIV-1 Positive, Antiretroviral Treatment-Naive Adults
Gilead Sciences
NCT01780506
Prevention of HIV Infection in High-Risk Social Networks of African American Men Who Have Sex With Men (MSM)
Medical College of Wisconsin
NCT01825252
Love, Sex & Choices: A Web Series on Mobile Devices to Reduce Black Women's HIV Risk
Northeastern University
NCT02493647
Study to Evaluate the Safety and Efficacy of Stribild Versus Atripla in Human Immunodeficiency Virus, Type 1 (HIV-1) Infected, Antiretroviral Treatment-Naive Adults
Gilead Sciences
NCT01095796
TMC114-C211: Trial of an Investigational Protease Inhibitor TMC114 With Ritonavir ("TMC114/r") in HIV-1 Infected Patients Who Have Never Been Treated With Antiretroviral Medications.
Tibotec Pharmaceuticals, Ireland
NCT00258557
Study of Recently HIV Infected Men and Transmission Behaviors
University of California, Los Angeles
NCT01201083
Community-based Interventions to Increase HIV Testing and HIV Care Utilization
Kaiser Permanente
NCT01867177
Integrating HIV and Hepatitis C Screening in an Urban Emergency Department
New York City Health and Hospitals Corporation
NCT03252483
Palliative Care in People Living With HIV/AIDS: Integrating Into Standard of Care
Children's National Research Institute
NCT01775436
A Technology-Delivered Peer-to-Peer Support ART Adherence Intervention for Substance-using HIV+ Adults
University of Minnesota
NCT02704208
The Health Access and Recovery Peer Program
Emory University
NCT01725815
Online HIV Prevention for Young Male Couples
Northwestern University
NCT03284541
Prospective Cohort Study of HIV and Zika in Infants and Pregnancy
Westat
NCT03263195
Connecting Resources for Urban Sexual Health
University of California, San Francisco
NCT02183909
VA Video Connect in HIV Care
VA Office of Research and Development
NCT04055207
Get Ready And Empowered About Treatment
University of Rochester
NCT02165735
Multimedia WORTH With Black Drug-Involved Women on Probation
Columbia University
NCT02391233
Safety and Pharmacokinetic Study of Oral MK-8527 QM in Participants at Low-Risk for HIV-1 Infection (MK-8527-007)
Merck Sharp & Dohme
NCT06045507
Brain Deficits in HIV/HCV Coinfected People Before and After Anti-HCV Therapy
University of California, Los Angeles
NCT00747539
HIV-related Accelerated Aging of the Airway Epithelium
Weill Medical College of Cornell University
NCT01974219
Quantification of Immune Cells in Women Using Contraception (CHIC II)
University of Pittsburgh
NCT01873170
Integrated Stepped Care for Unhealthy Alcohol Use in HIV
Yale University
NCT01410123
Risk Reduction Intervention for Vulnerable Young Adult Males
Hunter College of City University of New York
NCT01118416
Carolina Alcohol and Drug Resources
Duke University
NCT01791179
Men Together Making a Difference: Health Promotion for Black Men
University of Pennsylvania
NCT02572414
Comparing Brief Alcohol Interventions For HIV-HCV Co-infected Persons
Butler Hospital
NCT02316184
Functional Imaging Reserve in NeuroHIV
Washington University School of Medicine
NCT03596268
Nursing Intervention for HIV Regime Adherence Among People With Serious Mental Illness (SMI)
National Institute of Nursing Research (NINR)
NCT00264823
Efficacy of ART to Interrupt HIV Transmission Networks
University of California, San Diego
NCT02528773
Females of African American Legacy Empowering Self (FemAALES)
Charles Drew University of Medicine and Science
NCT02189876
Randomized Trial of an HIV Prevention and Relationship Education Program for Young Male Couples
Northwestern University
NCT03186534
Innovative Approaches for Minor Consent: Consent 2.0
Indiana University
NCT03242954
Project FIRST - Financial Incentives to Reduce Substance Use and Improve Treatment
Albert Einstein College of Medicine
NCT01376570
Home Self-Testing for HIV to Increase HIV Testing Frequency in Men Who Have Sex With Men (The iTest Study)
University of Washington
NCT01161446
PrEPTECH Phase 2 Study of a PrEP Telehealth Intervention
ETR Associates
NCT04902820
Speed of Processing Training in Adults With HIV
University of Alabama at Birmingham
NCT02758093
Treatment Advocacy Intervention for HIV-Positive African Americans
Boston Children's Hospital
NCT01350544
Behavioral Interventions to Reduce Heavy Drinking Among MSM in HIV Primary Care
Brown University
NCT02709759
Development and Pilot Testing of a PHCI for Emergency Department Patients Who Decline Rapid HIV/ HCV Screening
Rhode Island Hospital
NCT04137094
Expanding PrEP By Embedding Unannounced SNAPS Navigators in High STI Testing Clinical Sites
NYU Langone Health
NCT04207151
Providing Online Counseling for Home-Based HIV Testing With Transgender Youth
University of Michigan
NCT03185975
Manhattan HIV/Hepatology Brain Bank
Icahn School of Medicine at Mount Sinai
NCT00300209
Brief Alcohol Intervention for HIV-Infected Men Who Have Sex With Men (MSM) in a Primary Care Setting
Brown University
NCT01328743
Staying Well: A Clinical Trial of Mindfulness-Based Stress Reduction and Education Groups for HIV
University of California, San Francisco
NCT00271856
Accuracy of Hemoglobin A1C to Predict Glycemia in HIV
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00433628
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 32 |
| Phase 2 | 32 |
| Phase 3 | 12 |
| Phase 4 | 13 |
Top Sponsors
Named interventions
Most-linked intervention names on HIV records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on HIV trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this HIV page
304 registered trials, 109 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 109 HIV trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- National Institute of Allergy and Infectious Diseases (NIAID) sponsors the most HIV trials on record, review their full trial history before evaluating a specific study. See National Institute of Allergy and Infectious Diseases (NIAID)'s trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This HIV condition card totals 304 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.