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NCT02758093 · ClinicalTrials.gov registry record · NA
Speed of Processing Training in Adults With HIV
A NA study of HIV and Cognition - Other, sponsored by University of Alabama at Birmingham.
- Completed
- Registry status
- NA
- Development phase
- 217
- Enrollment target
- 1
- Study location
NCT02758093: Completed NA study of HIV and Cognition - Other, sponsored by University of Alabama at Birmingham.
NCT02758093 is a NA study of HIV and Cognition - Other that has completed, run by University of Alabama at Birmingham. The registered enrollment target is 217 participants, below the 439-participant average among 303 other HIV trials with a reported enrollment target (51% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02758093, a NA study of HIV and Cognition - Other, has completed, sponsored by University of Alabama at Birmingham.
- COMPLETED
- Registry status
- NA
- Development phase
- 217 participants
- Enrollment target
- 1
- Study location
Study Summary
As people age with HIV, the synergistic effects with normal age-related cognitive declines will accentuate and/or accelerate declines in cognitive functioning which can be detected as early in one's 40s. Although interventions are needed to protect/improve cognitive functioning, one intervention already exists to improve speed of processing. NINR/NIA (January 14, 2014) announced that Speed of Processing Training used in the ACTIVE Study (N = 2,802 community-dwelling older adults) has the ability to enable "older people to maintain their cognitive abilities as they age" even 10 years after training. As shown in the ACTIVE Study, this intervention uniquely improves driving, instrumental activities of daily living (IADL), health-related quality of life, self-rated health, internal locus of control, and protects one from depression; these represent areas of needed intervention for adults with HIV as well. In adults with HIV, previous pilot studies likewise indicate speed of processing declines are associated with poorer driving simulator performance and more self-reported at-fault automobile crashes; such speed of processing declines on driving alone represent a significant public health concern. These studies also demonstrated that Speed of Processing Training improved this cognitive ability and translated into improved performance on a timed measure of IADLs. Based on prior research, this RCT proposal consists of a pre-post two-year longitudinal experimental design whereby 264 adults with HIV, 40+ years and diagnosed with HIV-Associated Neurocognitive Disorder, will be randomly assigned to one of three training conditions: 1) 10 hours of laboratory-based Speed of Processing Training, 2) 20 hours of laboratory-based Speed of Processing Training, or 3) 10 hours of a standardized computer-contact control (sham) condition. AIM 1: Determine whether 10 vs 20 hours of speed of processing training will improve this cognitive ability at post-test, year 1, and year 2 after bas
Primary Outcome
Cognitive measures of speed of processing (i.e., Useful Field of View) will be used to determine whether the training was effective.
Conditions Studied
Interventions
- BEHAVIORAL Speed of Processing Training
- OTHER Internet Navigational
Study Locations (1)
Alabama
- University of Alabama at Birmingham - Birmingham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 217 participants |
| Start Date | 2016-09-28 |
| Est. Completion | 2020-03-11 |
| Phase | NA |
What the finished NCT02758093 record still lists
NCT02758093 is an interventional study that assigns participants to a tested intervention. The registered 217 participants enrollment target is mid-sized for trials with a published cap, below the 439-participant average among 303 other HIV trials with a reported enrollment target (51% lower).
The record links to 3 conditions, with HIV appearing as the primary indexed condition, and to 2 interventions - of which Speed of Processing Training is the first listed.
NCT02758093 reports a single indexed study location in Alabama.
Frequently Asked Questions
What is clinical trial NCT02758093 about?
NCT02758093 is a clinical study titled "Speed of Processing Training in Adults With HIV". As people age with HIV, the synergistic effects with normal age-related cognitive declines will accentuate and/or accelerate declines in cognitive functioning which can be detected as early in one's 40s. Although interventions are needed to protect/improve cognitive functioning, one intervention alr...
What is the current status of trial NCT02758093?
This trial is currently completed. It is a NA study. The enrollment target is 217 participants. The study started on 2016-09-28. Estimated completion is 2020-03-11.
What conditions does trial NCT02758093 study?
This clinical trial studies the following conditions: HIV, Cognition - Other, Impaired Driving.
What interventions are being tested in trial NCT02758093?
The interventions under investigation include: Speed of Processing Training (BEHAVIORAL), Internet Navigational (OTHER).
Who is sponsoring clinical trial NCT02758093?
This trial is sponsored by University of Alabama at Birmingham, which has 1,160 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02758093 being conducted?
This trial has 1 study location across Alabama. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT02758093's enrollment target sits among peer trials
217 97th of 303 higher than 207 of 303 other HIV trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other HIV trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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