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NCT01974219 · ClinicalTrials.gov registry record
HIV-related Accelerated Aging of the Airway Epithelium
A clinical trial of HIV and Smoking, sponsored by Weill Medical College of Cornell University.
- Completed
- Registry status
- 330
- Enrollment target
- 1
- Study location
NCT01974219 is a study of HIV and Smoking that has completed, run by Weill Medical College of Cornell University. The registered enrollment target is 330 participants, below the 439-participant average among 303 other HIV trials with a reported enrollment target (25% lower). The trial reports 1 study location across 1 state.
The verdict
NCT01974219, a study of HIV and Smoking, has completed, sponsored by Weill Medical College of Cornell University.
- COMPLETED
- Registry status
- 330 participants
- Enrollment target
- 1
- Study location
Study Summary
In cigarette smokers that are HIV+, one of the most common HIV-associated non-AIDS conditions is the accelerated development of chronic obstructive pulmonary disease (COPD), a disorder associated with significant morbidity and mortality. Based on the knowledge that COPD in smokers starts in the small airway epithelium, this study is focused on examining the hypothesis that the accelerated development of COPD associated with HIV infection results, in part, from an interaction of HIV directly on the small airway epithelium or through infection of cellular components of the immune system, with mediators released by these immune cells evoking premature biologic aging of the small airway epithelium. By identifying the early events in the pathogenesis of the HIV-associated accelerated COPD in smokers, we aim to identify biologic targets to which pharmacologic therapies could be addressed.
Conditions Studied
Study Locations (1)
New York
- Weill Cornell Medical College and Weill Cornell Medical Center, Department of Genetic Medicine - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 330 participants |
| Start Date | 2013-12-23 |
| Est. Completion | 2019-02-14 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01974219
The ClinicalTrials.gov registry entry for NCT01974219 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 330 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 439-participant average among 303 other HIV trials with a reported enrollment target (25% lower). The listed sponsor is Weill Medical College of Cornell University, which has 701 total studies on file at ClinicalTrials.gov.
The record links to 4 conditions, with HIV appearing as the primary indexed condition, and to 0 interventions.
NCT01974219 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.
Frequently Asked Questions
What is clinical trial NCT01974219 about?
NCT01974219 is a clinical study titled "HIV-related Accelerated Aging of the Airway Epithelium". In cigarette smokers that are HIV+, one of the most common HIV-associated non-AIDS conditions is the accelerated development of chronic obstructive pulmonary disease (COPD), a disorder associated with significant morbidity and mortality. Based on the knowledge that COPD in smokers starts in the smal...
What is the current status of trial NCT01974219?
This trial is currently completed. The enrollment target is 330 participants. The study started on 2013-12-23. Estimated completion is 2019-02-14.
What conditions does trial NCT01974219 study?
This clinical trial studies the following conditions: HIV, Smoking, Chronic Obstructive Pulmonary Disease, COPD.
Who is sponsoring clinical trial NCT01974219?
This trial is sponsored by Weill Medical College of Cornell University, which has 701 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01974219 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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