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NCT01780506 · ClinicalTrials.gov registry record · Phase 3

Study to Evaluate the Safety and Efficacy of E/C/F/TAF (Genvoya®) Versus E/C/F/TDF (Stribild®) in HIV-1 Positive, Antiretroviral Treatment-Naive Adults

A Phase 3 study of HIV Infections and HIV, sponsored by Gilead Sciences.

Completed
Registry status
Phase 3
Development phase
872
Enrollment target
20
Study locations

NCT01780506 is a Phase 3 study of HIV Infections and HIV that has completed, run by Gilead Sciences. The registered enrollment target is 872 participants, above the 444-participant average among 542 other HIV Infections trials with a reported enrollment target (96% higher). The trial reports 20 study locations across 7 states.

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The verdict

NCT01780506, a Phase 3 study of HIV Infections and HIV, has completed, sponsored by Gilead Sciences.

COMPLETED
Registry status
Phase 3
Development phase
872 participants
Enrollment target
20
Study locations

Study Summary

The primary objective of this study is to evaluate the efficacy of elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (E/C/F/TAF) fixed-dose combination (FDC) versus elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate (E/C/F/TDF) FDC in HIV-1 positive, antiretroviral treatment-naive adults.

Conditions Studied

Interventions

  • DRUG E/C/F/TAF
  • DRUG E/C/F/TDF
  • DRUG E/C/F/TDF Placebo
  • DRUG E/C/F/TAF Placebo

Study Locations (20)

California

  • Kaiser Permanente Los Angeles - Los Angeles
  • University of California, Los Angeles - Los Angeles
  • Peter J. Ruane, MD, Inc. - Los Angeles
  • Anthony Mills MD Inc - Los Angeles
  • East Bay AIDS Center - Oakland
  • Kaiser Permanente - Sacramento - Sacramento
  • La Playa Medical Group and Clinical Research - San Diego
  • University of California, San Diego - San Diego
  • Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center - Torrance

Florida

  • Gary Richmond, MD, PA, Inc. - Fort Lauderdale
  • Midway Immunology & Research Center, LLC - Ft. Pierce
  • The Kinder Medical Group - Miami
  • AIDS Healthcare Foundation - Miami Beach

District of Columbia

  • Dupont Circle Physicians Group, P.C. - Washington D.C.
  • Whitman Walker Clinic - Washington D.C.
  • Capital Medical Associates, P.C. - Washington D.C.

Alabama

  • The University of Alabama at Birmingham - Birmingham

Arizona

  • Spectrum Medical Group - Phoenix

Colorado

  • Apex Research, LLC - Denver

Connecticut

  • Yale University School of Medicine - New Haven

Trial Details

FieldValue
Enrollment Target 872 participants
Start Date 2012-12-26
Est. Completion 2017-09-06
Phase Phase 3

Sponsor

Gilead Sciences

504 total trials

What the Registry Record Tells You About NCT01780506

The ClinicalTrials.gov registry entry for NCT01780506 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 872 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 444-participant average among 542 other HIV Infections trials with a reported enrollment target (96% higher). The listed sponsor is Gilead Sciences, which has 504 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with HIV Infections appearing as the primary indexed condition, and to 4 interventions - of which E/C/F/TAF is the first listed.

NCT01780506 reports 20 study locations spanning 7 distinct geographic areas - top geographies include California, Florida, District of Columbia.

Frequently Asked Questions

What is clinical trial NCT01780506 about?

NCT01780506 is a clinical study titled "Study to Evaluate the Safety and Efficacy of E/C/F/TAF (Genvoya®) Versus E/C/F/TDF (Stribild®) in HIV-1 Positive, Antiretroviral Treatment-Naive Adults". The primary objective of this study is to evaluate the efficacy of elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (E/C/F/TAF) fixed-dose combination (FDC) versus elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate (E/C/F/TDF) FDC in HIV-1 positive, antiretroviral treatme...

What is the current status of trial NCT01780506?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 872 participants. The study started on 2012-12-26. Estimated completion is 2017-09-06.

What conditions does trial NCT01780506 study?

This clinical trial studies the following conditions: HIV Infections, HIV.

What interventions are being tested in trial NCT01780506?

The interventions under investigation include: E/C/F/TAF (DRUG), E/C/F/TDF (DRUG), E/C/F/TDF Placebo (DRUG), E/C/F/TAF Placebo (DRUG).

Who is sponsoring clinical trial NCT01780506?

This trial is sponsored by Gilead Sciences, which has 504 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01780506 being conducted?

This trial has 20 study locations across Alabama, Arizona, California, Colorado, Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.