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Fibromyalgia: early-phase trial registry
26 of 77 indexed Fibromyalgia trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #175 of 28,707 conditions by registered trial count.
77 US clinical trials · 26 currently recruiting · #175 of 28,707 conditions by registered trial count
Fibromyalgia: 77 US clinical trials tracked, 26 recruiting.
Fibromyalgia is the subject of 77 registered US clinical trials on ClinicalTrials.gov, 26 of them currently open to new participants. 10 are in Phase 3-4 (later-stage) and 18 in Phase 1-2 (earlier-stage). The most active sponsor is University of Michigan, running 6 of these trials.
Enrollment posture brief
Registry condition fibromyalgia
OPEN 26 | RECR 34% | LATE 10 | EARLY 18 | RANK #175 | SPON 6
Volume-matched condition peers
Nearest open-share peer: Breast Cancer (34% recruiting · 1,251 trials)
Fibromyalgia lists 26 open slots (34% of 77 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Fibromyalgia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Fibromyalgia is recruiting below its size-band peers.
26 of 77 indexed trials (33.8%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Fibromyalgia trials is spread across many organizations.
University of Michigan accounts for 6 of 77 trials (7.8%). 53 distinct sponsors appear on at least one study for this condition label.
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Typical Fibromyalgia enrolment sits around 66 participants.
Median target enrolment is 66 among the 77 trials that report a genuine target (sentinel values excluded). 44 of those (57.1%) plan for fewer than 100 participants.
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Fibromyalgia research is mostly interventional.
68 interventional and 9 observational studies make up this index (88.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
77 total, page 1 of 2
Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA
Brown University
NCT05754190
Fibromyalgia Response With Esreboxetine Evaluated Using a Randomized Withdrawal Research Design
Axsome Therapeutics
NCT07398417
Autoimmune Intervention Mastery Course Study
Terry L. Wahls
NCT05057676
Fibromyalgia Sleep A to ZZZ Study
University of Michigan
NCT06567886
Supraspinal Processing of Sensory Aspects of Pain
Children's Hospital Medical Center, Cincinnati
NCT05814497
Auricular Neuromodulation in Veterans With Fibromyalgia
VA Office of Research and Development
NCT06415591
Ultrasonic Neuromodulation of Cingulate Cortex for Fibromyalgia
SPIRE Therapeutics
NCT07226648
Explosive Synchronization of Brain Network Activity in Chronic Pain
University of Michigan
NCT04606095
Pain Processing in Inflammatory and Non-Inflammatory Chronic Pain Syndromes
University of Florida
NCT05277025
Brief Pain Exposure Therapy (BPET) For Nociplastic Pain
University of Michigan
NCT06208514
Assessment of Neuroinflammation in Central Inflammatory Disorders Using [F-18]DPA-714.
University of Alabama at Birmingham
NCT03759522
Duloxetine Metabolism and Fibromyalgia
University of Utah
NCT06866444
Cognitive Training to Enhance Brain Concordance During Acupuncture
Spaulding Rehabilitation Hospital
NCT06157866
Development of a Therapeutic Endpoint in Pediatric Rheumatologic Conditions
Children's National Research Institute
NCT04833465
Neural Mechanisms of Light Driven Analgesia
University of North Carolina, Chapel Hill
NCT07245303
Relationships of Affect and Neuroinflammation With Clinical Pain in Veterans With Fibromyalgia
VA Office of Research and Development
NCT06574165
Vagus Nerve Stimulation(VNS) As Treatment For Fibromyalgia Patients
Massachusetts General Hospital
NCT06009159
Nitrous Oxide as Treatment for Fibromyalgia
University of Chicago
NCT05357066
Analgesic Response to Opioids in Patients With Fibromyalgia After Conventional Acupuncture Versus Sham Acupuncture
University of California, Irvine
NCT06571110
Effects of Breathing and Attention Training (BAT) on Pain Modulation
University of Florida
NCT05773482
Self-regulation of Real-time fMRI Brain Activity in Chronic Pain
Brigham and Women's Hospital
NCT07023523
The Benefits of Natural Medicine, Vitamin IV Therapy and Supplements: Maintaining Good Health Through Nature
Faith A. Richardson
NCT05067998
The Effects of Energy Healing in Fibromyalgia
University of California, Irvine
NCT06552728
The Effects of Core Shamanism in Fibromyalgia
University of California, Irvine
NCT06579261
MDMA-assisted Therapy for Fibromyalgia
Spaulding Rehabilitation Hospital
NCT06066853
Evaluation of the Safety and Efficacy of a Full-Body Electrostimulation Garment for Individuals With Neurological and Neuromuscular Conditions That Cause Spasticity, Hyperreflexia, and Pain
Shirley Ryan AbilityLab
NCT07132775
Virtual Specialty Clinic for Fibromyalgia Care
Swing Therapeutics
NCT05978297
PEACE: Comparing Chronic Pain Treatment Options
Memorial Sloan Kettering Cancer Center
NCT02979574
The Clinical Impact of Integrated Behavioral Health Techniques in Patients With Fibromyalgia
Mayo Clinic
NCT06988761
Two Point Discrimination
Children's Hospital Medical Center, Cincinnati
NCT03686748
Microcurrent for Fibromyalgia
Paul Crawford
NCT04949100
A Study Of Virtual Reality Vs Sham VR On Fibromyalgia
Mayo Clinic
NCT07202572
Study of Milnacipran for the Treatment of Fibromyalgia
Forest Laboratories
NCT00314249
Quantitative EEG During PSG in Patients With and Without Fibromyalgia
SouthCoast Medical Group
NCT01674179
Fibromyalgia TENS in Physical Therapy Study (TIPS): an Embedded Pragmatic Clinical Trial
Kathleen Sluka
NCT04683042
Fibromyalgia Integrative Training for Adolescents With Juvenile Fibromyalgia
Children's Hospital Medical Center, Cincinnati
NCT03268421
Fibromyalgia Activity Study With Transcutaneous Electrical Nerve Stimulation (FAST)
Kathleen Sluka
NCT01888640
Resilience Skills Self-Management for Chronic Pain.
University of Michigan
NCT03304613
Nondrug Treatment Programs for Adults With Fibromyalgia
University of Utah
NCT00088777
Comprehensive vs. Assisted Management of Mood and Pain Symptoms
VA Office of Research and Development
NCT01757301
Subgroups of Fibromyalgia Syndrome (FMS): Symptoms, Beliefs, and Tailored Treatment
University of Washington
NCT00762125
Central Mechanisms of Chronic Pain and Fatigue Subtitle: Functional Imaging of Brain and Spinal Cord
University of Florida
NCT03075254
Gabapentin in Fibromyalgia Trial (GIFT)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NCT00057278
Basket Study (CT-100-002) to Evaluate the Effects of a DiNaMo™ Component Training
Click Therapeutics
NCT05573685
Effects Of Pregabalin (Lyrica) On Sleep Maintenance In Subjects With Fibromyalgia
Pfizer's Upjohn has merged with Mylan to form Viatris
NCT00883740
Cognitive Behavioral Insomnia Therapy for Individuals With Fibromyalgia
Duke University
NCT00321451
D-Ribose for Fatigue in Subjects With Fibromyalgia
RiboCor
NCT01315210
Developing Biomarkers for Fibromyalgia
University of Michigan
NCT00932061
Treatment of Fibromyalgia With Recovery Factors
Practitioners Alliance Network
NCT04381780
Pain Management Techniques for Fibromyalgia
University of Michigan
NCT00086060
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 6 |
| Phase 2 | 12 |
| Phase 3 | 6 |
| Phase 4 | 4 |
Top Sponsors
Named interventions
Most-linked intervention names on Fibromyalgia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Fibromyalgia trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Fibromyalgia page
77 registered trials, 26 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 26 Fibromyalgia trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Michigan sponsors the most Fibromyalgia trials on record, review their full trial history before evaluating a specific study. See University of Michigan's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Fibromyalgia condition card totals 77 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.