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Fibromyalgia
Open-data reference.
77 US clinical trials · 26 currently recruiting
Active & Recent Trials
Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA
Brown University
NCT05754190
Fibromyalgia Response With Esreboxetine Evaluated Using a Randomized Withdrawal Research Design
Axsome Therapeutics
NCT07398417
Autoimmune Intervention Mastery Course Study
Terry L. Wahls
NCT05057676
Fibromyalgia Sleep A to ZZZ Study
University of Michigan
NCT06567886
Supraspinal Processing of Sensory Aspects of Pain
Children's Hospital Medical Center, Cincinnati
NCT05814497
Auricular Neuromodulation in Veterans With Fibromyalgia
VA Office of Research and Development
NCT06415591
Ultrasonic Neuromodulation of Cingulate Cortex for Fibromyalgia
SPIRE Therapeutics
NCT07226648
Explosive Synchronization of Brain Network Activity in Chronic Pain
University of Michigan
NCT04606095
Pain Processing in Inflammatory and Non-Inflammatory Chronic Pain Syndromes
University of Florida
NCT05277025
Brief Pain Exposure Therapy (BPET) For Nociplastic Pain
University of Michigan
NCT06208514
Assessment of Neuroinflammation in Central Inflammatory Disorders Using [F-18]DPA-714.
University of Alabama at Birmingham
NCT03759522
Duloxetine Metabolism and Fibromyalgia
University of Utah
NCT06866444
Cognitive Training to Enhance Brain Concordance During Acupuncture
Spaulding Rehabilitation Hospital
NCT06157866
Development of a Therapeutic Endpoint in Pediatric Rheumatologic Conditions
Children's National Research Institute
NCT04833465
Neural Mechanisms of Light Driven Analgesia
University of North Carolina, Chapel Hill
NCT07245303
Relationships of Affect and Neuroinflammation With Clinical Pain in Veterans With Fibromyalgia
VA Office of Research and Development
NCT06574165
Vagus Nerve Stimulation(VNS) As Treatment For Fibromyalgia Patients
Massachusetts General Hospital
NCT06009159
Nitrous Oxide as Treatment for Fibromyalgia
University of Chicago
NCT05357066
Analgesic Response to Opioids in Patients With Fibromyalgia After Conventional Acupuncture Versus Sham Acupuncture
University of California, Irvine
NCT06571110
Effects of Breathing and Attention Training (BAT) on Pain Modulation
University of Florida
NCT05773482
Self-regulation of Real-time fMRI Brain Activity in Chronic Pain
Brigham and Women's Hospital
NCT07023523
The Benefits of Natural Medicine, Vitamin IV Therapy and Supplements: Maintaining Good Health Through Nature
Faith A. Richardson
NCT05067998
The Effects of Energy Healing in Fibromyalgia
University of California, Irvine
NCT06552728
The Effects of Core Shamanism in Fibromyalgia
University of California, Irvine
NCT06579261
MDMA-assisted Therapy for Fibromyalgia
Spaulding Rehabilitation Hospital
NCT06066853
Evaluation of the Safety and Efficacy of a Full-Body Electrostimulation Garment for Individuals With Neurological and Neuromuscular Conditions That Cause Spasticity, Hyperreflexia, and Pain
Shirley Ryan AbilityLab
NCT07132775
Virtual Specialty Clinic for Fibromyalgia Care
Swing Therapeutics
NCT05978297
PEACE: Comparing Chronic Pain Treatment Options
Memorial Sloan Kettering Cancer Center
NCT02979574
The Clinical Impact of Integrated Behavioral Health Techniques in Patients With Fibromyalgia
Mayo Clinic
NCT06988761
Two Point Discrimination
Children's Hospital Medical Center, Cincinnati
NCT03686748
Microcurrent for Fibromyalgia
Paul Crawford
NCT04949100
A Study Of Virtual Reality Vs Sham VR On Fibromyalgia
Mayo Clinic
NCT07202572
Study of Milnacipran for the Treatment of Fibromyalgia
Forest Laboratories
NCT00314249
Quantitative EEG During PSG in Patients With and Without Fibromyalgia
SouthCoast Medical Group
NCT01674179
Fibromyalgia TENS in Physical Therapy Study (TIPS): an Embedded Pragmatic Clinical Trial
Kathleen Sluka
NCT04683042
Fibromyalgia Integrative Training for Adolescents With Juvenile Fibromyalgia
Children's Hospital Medical Center, Cincinnati
NCT03268421
Fibromyalgia Activity Study With Transcutaneous Electrical Nerve Stimulation (FAST)
Kathleen Sluka
NCT01888640
Resilience Skills Self-Management for Chronic Pain.
University of Michigan
NCT03304613
Nondrug Treatment Programs for Adults With Fibromyalgia
University of Utah
NCT00088777
Comprehensive vs. Assisted Management of Mood and Pain Symptoms
VA Office of Research and Development
NCT01757301
Subgroups of Fibromyalgia Syndrome (FMS): Symptoms, Beliefs, and Tailored Treatment
University of Washington
NCT00762125
Central Mechanisms of Chronic Pain and Fatigue Subtitle: Functional Imaging of Brain and Spinal Cord
University of Florida
NCT03075254
Gabapentin in Fibromyalgia Trial (GIFT)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NCT00057278
Basket Study (CT-100-002) to Evaluate the Effects of a DiNaMo™ Component Training
Click Therapeutics
NCT05573685
Effects Of Pregabalin (Lyrica) On Sleep Maintenance In Subjects With Fibromyalgia
Pfizer's Upjohn has merged with Mylan to form Viatris
NCT00883740
Cognitive Behavioral Insomnia Therapy for Individuals With Fibromyalgia
Duke University
NCT00321451
D-Ribose for Fatigue in Subjects With Fibromyalgia
RiboCor
NCT01315210
Developing Biomarkers for Fibromyalgia
University of Michigan
NCT00932061
Treatment of Fibromyalgia With Recovery Factors
Practitioners Alliance Network
NCT04381780
Pain Management Techniques for Fibromyalgia
University of Michigan
NCT00086060
A Study To Assess Esreboxetine's Effect On Concentration, Memory, Decision Making And Problem Solving In Patients With Fibromyalgia.
Pfizer
NCT00752505
Mechanisms of Affective Touch in Chronic Pain
Laura Case
NCT04206397
Healing Through Affective Self-Awareness in Fibromyalgia: a Randomized Controlled Trial
Mike Hsu
NCT00437411
Tai Chi Mind-Body Therapy for Fibromyalgia
Tufts Medical Center
NCT00515008
Heart Rate Variability in Response to Metformin Challenge
Woodinville Psychiatric Associates
NCT02500628
Prospective Study to Evaluate a Digital Regimen for Fibromyalgia Management: An Extension Study
Swing Therapeutics
NCT05433337
Cranial Electrical Stimulation Effects on Symptoms in Persons With Fibromyalgia
University of Virginia
NCT00928720
Making Better Lives: Patient-Focused Care for Low Back Pain (LBP)
VA Office of Research and Development
NCT02697435
Novel Use of (Oral) Ketotifen for the Treatment of Fibromyalgia: A Pilot Study
Indiana University
NCT01553318
The Exercise Response to Pharmacologic Cholinergic Stimulation in Myalgic Encephalomyelitis / Chronic Fatigue Syndrome
Brigham and Women's Hospital
NCT03674541
Quetiapine Compared With Placebo in the Management of Fibromyalgia
East Tennessee State University
NCT01458964
Intravenous Micronutrient Therapy (IVMT) for Fibromyalgia
National Center for Complementary and Integrative Health (NCCIH)
NCT00067405
The Effect of Milnacipran in Patients With Fibromyalgia
Beth Israel Medical Center
NCT01108731
Pain Rehabilitation Virtual Reality (PRVR): Innovations to Enhance Mobility in the Presence of Pain
Stanford University
NCT04636177
A Pilot Study on the Use of Nociceptive Flexion Reflex for Fibromyalgia
Indiana University
NCT00965601
Generalized Hypersensitivity in Patients With Fibromyalgia Syndrome
University of Florida
NCT04415866
Dextromethorphan in Fibromyalgia
University of Alabama at Birmingham
NCT03538054
Effect of Repetitive Transcranial Direct Current Stimulation (tDCS) on Chronic Pelvic Pain
Summa Health System
NCT00554320
Effect of Temperature on Pain and Brown Adipose Activity in Fibromyalgia
University of Minnesota
NCT01322425
Prospective Evaluation of Reduced Impedance Noninvasive Cortical Electrostimulation (RINCE) to Reduce Fibromyalgia Effects - Extension Study
Cerephex Corporation
NCT01958853
The Effects of Milnacipran on Sleep Disturbance in Fibromyalgia
Mansoor Ahmed M.D.
NCT01234675
Transcranial Magnetic Stimulation for Treating Women With Chronic Widespread Pain
University of Washington
NCT00524420
Veteran Ear Acupuncture Pilot Project
Chillicothe VA Medical Center
NCT04208659
Remote Gamified Sensory Perceptual Training for Patients With Fibromyalgia: a Feasibility Trial
Icahn School of Medicine at Mount Sinai
NCT04919525
Effect of Milnacipran on Pain in Fibromyalgia
University of California, San Diego
NCT01288807
TD-9855 Mass Balance Study
Theravance Biopharma
NCT01924143
Safety and Efficacy of Fluoxetine in Juvenile Fibromyalgia
University of Cincinnati
NCT00115804
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 6 |
| Phase 2 | 12 |
| Phase 3 | 6 |
| Phase 4 | 4 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Fibromyalgia Trial Landscape
ClinicalTrials.gov lists 77 US studies indexed under Fibromyalgia, and 26 of those are currently open to recruitment — roughly 34% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Fibromyalgia shows 10 late-stage studies (Phase 3 and Phase 4 combined) alongside 18 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Fibromyalgia is led by University of Michigan with 6 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 77 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Fibromyalgia?
PlainTrial tracks 77 US clinical trials for Fibromyalgia, of which 26 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Fibromyalgia?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.