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ClinicalTrials.gov 24 recruiting now later-stage tilt

ADHD: later-stage trial registry

24 of 77 indexed ADHD trials are currently recruiting, with more weight in Phase 3-4.

Corpus placement: #175 of 28,707 conditions by registered trial count.

77 US clinical trials · 24 currently recruiting · #175 of 28,707 conditions by registered trial count

ADHD: 77 US clinical trials tracked, 24 recruiting.

ADHD is the subject of 77 registered US clinical trials on ClinicalTrials.gov, 24 of them currently open to new participants. 20 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is Duke University, running 4 of these trials.

Enrollment posture brief

Registry condition adhd

OPEN 24 | RECR 31% | LATE 20 | EARLY 9 | RANK #175 | SPON 4

Nearest open-share peer: Eosinophilic Esophagitis (31% recruiting · 45 trials)

Acute Kidney Injury44%Tobacco Use42.9%Fibromyalgia33.8%ADHD (this)31%Age-related Macular Degenera26.7%
Open-enrollment share among volume-matched conditions near ADHD

ADHD lists 24 open slots (31% of 77 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for ADHD on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. ADHD is recruiting below its size-band peers.

    24 of 77 indexed trials (31.2%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of ADHD trials is spread across many organizations.

    Duke University accounts for 4 of 77 trials (5.2%). 52 distinct sponsors appear on at least one study for this condition label.

  3. Typical ADHD enrolment sits around 72 participants.

    Median target enrolment is 72 among the 76 trials that report a genuine target (sentinel values excluded). 41 of those (53.9%) plan for fewer than 100 participants.

  4. ADHD research is mostly interventional.

    67 interventional and 10 observational studies make up this index (87% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 16Phase 23Phase 310Phase 410

Open and recent trials

77 total, page 1 of 2

RECRUITING Phase 4 500 participants

Carboxylesterase 1 Genetic Variation and Methylphenidate in ADHD

Icahn School of Medicine at Mount Sinai

NCT03781752

RECRUITING Phase 4 500 participants

AWARE: Management of ADHD in Autism Spectrum Disorder

Daniel Coury

NCT05916339

RECRUITING Phase 3 308 participants

P3b Short-term Study of CTN in Patients With ADHD and Comorbid Anxiety

Otsuka Pharmaceutical Development & Commercialization

NCT06973577

RECRUITING 250 participants

Advancing Identification of Circadian Delay in ADHD Youth: Associations With Clinical Heterogeneity and Cognition

Duke University

NCT06971640

RECRUITING NA 200 participants

Central Executive Training and Parent Training for ADHD

Florida State University

NCT05492422

RECRUITING NA 130 participants

Target ADHD Executive Working Memory Replication Study

Hartford Hospital

NCT06446284

RECRUITING NA 120 participants

A Comparative Study to Evaluate a Novel Algorithm As a Diagnostic Aid for ADHD in Youth Ages 6-17.

MindTension

NCT06728969

RECRUITING NA 109 participants

Fidgeting and Attentional and Emotional Regulation in ADHD

University of California, Davis

NCT04526600

RECRUITING Phase 4 100 participants

Evaluating Treatment of ADHD in Children with Down Syndrome

Children's Hospital Medical Center, Cincinnati

NCT04219280

RECRUITING 100 participants

Studies of Brain and Body Interaction

Rutgers University

NCT03672266

RECRUITING NA 90 participants

A Study to Evaluate the Effects of a Supplement on the Side Effects Associated With Stimulant Medications

Outliers

NCT07380412

RECRUITING NA 65 participants

Impact of Parental Emotion Regulation on the Treatment of ADHD

Milton S. Hershey Medical Center

NCT05299814

RECRUITING NA 60 participants

Digital Health Intervention for Children With ADHD

University of California, Riverside

NCT06456372

RECRUITING NA 50 participants

Rural Autistic Individuals - Supporting Expression

Montana State University

NCT07054866

RECRUITING NA 50 participants

Accelerated iTBS Targeting of Working Memory Versus Inhibitory Control in Adolescent ADHD

Bradley Hospital

NCT07219810

RECRUITING 50 participants

Evaluate the Effects of Long-term Use of Psychotropic Medications on Eye Movement Patterns With the Gaize Device

Gaize

NCT07389473

RECRUITING NA 50 participants

Virtual Reality Attention Management

University of California, Davis

NCT03221244

RECRUITING Phase 4 44 participants

Stimulant vs. Non-stimulant Treatments and Reward Processing in Drug-naive Youth at SUD Risk

Icahn School of Medicine at Mount Sinai

NCT03781765

RECRUITING Phase 1 42 participants

A Trial to Assess How Centanafadine Interacts With Stimulants in the Body

Otsuka Pharmaceutical Development & Commercialization

NCT07314333

RECRUITING NA 36 participants

Comparative Efficacy of Organizational Skills Training (OST) and Mindfulness-Based Intervention (MBI)

Seattle Children's Hospital

NCT07281092

RECRUITING NA 36 participants

A Pilot Study of a Remote ADHD Monitoring Program

IDeA States Pediatric Clinical Trials Network

NCT06743425

RECRUITING NA 30 participants

Comparative Efficacy of Organizational Skills Training (OST) and Mindfulness-Based Intervention (MBI)

Duke University

NCT07089745

RECRUITING 21 participants

Impact of Sulphonylureas on Neurodevelopmental Outcomes in KCNJ11-related Intermediate Developmental Delay, Epilepsy and Neonatal Diabetes (iDEND) Syndrome

Royal Devon and Exeter NHS Foundation Trust

NCT05751525

RECRUITING NA 10 participants

Moms Managing Attention-Deficit/Hyperactivity Disorder (ADHD) Study

University of Pittsburgh

NCT06540547

ACTIVE NOT RECRUITING NA 300 participants

Reducing Disparities in Behavioral Health Treatment for Children in Primary Care

Children's Hospital of Philadelphia

NCT04082234

ACTIVE NOT RECRUITING Phase 4 288 participants

Single and Combined Effects of Behavioral, Academic, and Medication Treatments for ADHD in the Classroom

Florida International University

NCT05469386

ACTIVE NOT RECRUITING Phase 3 240 participants

Treating Parents with ADHD and Their Young Children Via Telehealth: a Hybrid Type I Effectiveness-Implementation Trial

University of Maryland, College Park

NCT04240756

ACTIVE NOT RECRUITING 198 participants

EndeavorOTC™ Prospective Product Registry

Akili Interactive Labs

NCT06109051

ACTIVE NOT RECRUITING NA 194 participants

An Adjunct Study to Assess Guided ADHD Therapy for Managing the Extent and Severity of Symptoms

Lumos Labs

NCT05805176

ACTIVE NOT RECRUITING 150 participants

EndeavorRx® Prospective Product Registry ("Expedition EndeavorRx")

Akili Interactive Labs

NCT05991167

ACTIVE NOT RECRUITING NA 146 participants

tRNS Treatment for ADHD Symptoms

Innosphere

NCT06189703

ACTIVE NOT RECRUITING NA 120 participants

Evaluating Stress Management Strategies Within the School Readiness Parenting Program

Florida International University

NCT06626750

ACTIVE NOT RECRUITING NA 106 participants

Testing "SupporT for ADHD and Related Treatment" (START) for Families of Children With ADHD

Ann & Robert H Lurie Children's Hospital of Chicago

NCT05796427

ACTIVE NOT RECRUITING NA 25 participants

A Trial of Two-Week Brain Stimulation for Teenagers With ADHD

Bradley Hospital

NCT05102864

ACTIVE NOT RECRUITING NA 6 participants

Flashed Light Therapy for Adolescents With ADHD and Delayed Sleep Timing

University of California, Los Angeles

NCT06036420

COMPLETED 4,193 participants

National Child Traumatic Stress Network (NCTSN) Quality Improvement Initiative Database

Hugo W. Moser Research Institute at Kennedy Krieger

NCT01591694

COMPLETED Phase 4 577 participants

Evaluation of an Intervention for Improving Community-based Pediatric Attention-Deficit Hyperactivity Disorder (ADHD) Care

Children's Hospital Medical Center, Cincinnati

NCT01143701

COMPLETED NA 560 participants

Guided ADHD Therapy for Managing the Extent and Severity of Symptoms

Lumos Labs

NCT05296473

COMPLETED Phase 2 370 participants

Dose-Finding Study to Evaluate the Efficacy and Safety of Modafinil as Treatment for Adults With ADHD

Cephalon

NCT00315276

COMPLETED Phase 3 360 participants

PRC-063 in Adolescent ADHD

Rhodes Pharmaceuticals, L.P.

NCT02139111

COMPLETED 312 participants

Adolescent Changes in Brain and Behavior in Boys and Girls With ADHD

Hugo W. Moser Research Institute at Kennedy Krieger

NCT05927506

COMPLETED Phase 4 297 participants

A Double-Blind Comparison of Concerta and Placebo in Adults With Attention Deficit Hyperactivity Disorder

Massachusetts General Hospital

NCT00181571

COMPLETED Phase 2 295 participants

A Study of TD-9855 in Adults With Attention-Deficit/Hyperactivity Disorder (ADHD)

Theravance Biopharma

NCT01458340

COMPLETED Phase 3 288 participants

PRC-063 Adult Laboratory Classroom Study in Adults With Attention-Deficit/Hyperactivity Disorder (ADHD)

Purdue Pharma, Canada

NCT03618030

COMPLETED Phase 3 255 participants

Smoking Cessation for Adults With Attention Deficit Hyperactivity Disorder (ADHD)

University of Cincinnati

NCT00253747

COMPLETED NA 251 participants

Central Executive Training (CET) for ADHD

Florida State University

NCT03324464

COMPLETED Phase 3 230 participants

Efficacy and Safety of Methylphenidate HCl ER Capsules in Children and Adolescents With ADHD

Rhodes Pharmaceuticals, L.P.

NCT01239030

COMPLETED Phase 3 217 participants

Evaluate the Efficacy &Safety of Methylphenidate Transdermal System (MTS) in Adolescents Aged 13-17 Years With ADHD

Noven Therapeutics

NCT00499863

COMPLETED Phase 3 156 participants

PRC-063 Classroom Study in Children (6-12 Years of Age) With ADHD

Purdue Pharma, Canada

NCT03172481

COMPLETED Phase 2 115 participants

Treatment of Adult Attention Deficit Hyperactivity Disorder (ADHD) in Methadone Patients - 1

New York State Psychiatric Institute

NCT00061087

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Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 3
Phase 3 10
Phase 4 10

Named interventions

Most-linked intervention names on ADHD records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
12 trials
Methylphenidate Drug
4 trials
Organizational Skills Training Behavioral
3 trials
PRC-063 oral capsules Drug
2 trials
TD-9855 Drug
2 trials
ADHD Therapy Device
2 trials
Placebo oral capsules Drug
2 trials
Behavioral Parent Training (BPT) Behavioral
2 trials

US sites by state

Facility locations filed on ADHD trials. A trial with sites in several states counts in each.

Florida 17 trials
California 17 trials
New York 15 trials
Massachusetts 13 trials
Ohio 11 trials
Pennsylvania 9 trials
North Carolina 9 trials
Nevada 8 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this ADHD page

77 registered trials, 24 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This ADHD condition card totals 77 registered trials; most-linked intervention Placebo; top US site state Florida. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.