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2026 data Public-data reference. official source

ADHD

Open-data reference.

76 US clinical trials · 23 currently recruiting

Active & Recent Trials

RECRUITING Phase 4 500 participants

Carboxylesterase 1 Genetic Variation and Methylphenidate in ADHD

Icahn School of Medicine at Mount Sinai

NCT03781752

RECRUITING Phase 4 500 participants

AWARE: Management of ADHD in Autism Spectrum Disorder

Daniel Coury

NCT05916339

RECRUITING Phase 3 308 participants

P3b Short-term Study of CTN in Patients With ADHD and Comorbid Anxiety

Otsuka Pharmaceutical Development & Commercialization

NCT06973577

RECRUITING 250 participants

Advancing Identification of Circadian Delay in ADHD Youth: Associations With Clinical Heterogeneity and Cognition

Duke University

NCT06971640

RECRUITING NA 200 participants

Central Executive Training and Parent Training for ADHD

Florida State University

NCT05492422

RECRUITING NA 130 participants

Target ADHD Executive Working Memory Replication Study

Hartford Hospital

NCT06446284

RECRUITING NA 120 participants

A Comparative Study to Evaluate a Novel Algorithm As a Diagnostic Aid for ADHD in Youth Ages 6-17.

MindTension

NCT06728969

RECRUITING NA 109 participants

Fidgeting and Attentional and Emotional Regulation in ADHD

University of California, Davis

NCT04526600

RECRUITING Phase 4 100 participants

Evaluating Treatment of ADHD in Children with Down Syndrome

Children's Hospital Medical Center, Cincinnati

NCT04219280

RECRUITING NA 90 participants

A Study to Evaluate the Effects of a Supplement on the Side Effects Associated With Stimulant Medications

Outliers

NCT07380412

RECRUITING NA 65 participants

Impact of Parental Emotion Regulation on the Treatment of ADHD

Milton S. Hershey Medical Center

NCT05299814

RECRUITING NA 60 participants

Digital Health Intervention for Children With ADHD

University of California, Riverside

NCT06456372

RECRUITING NA 50 participants

Rural Autistic Individuals - Supporting Expression

Montana State University

NCT07054866

RECRUITING NA 50 participants

Accelerated iTBS Targeting of Working Memory Versus Inhibitory Control in Adolescent ADHD

Bradley Hospital

NCT07219810

RECRUITING 50 participants

Evaluate the Effects of Long-term Use of Psychotropic Medications on Eye Movement Patterns With the Gaize Device

Gaize

NCT07389473

RECRUITING NA 50 participants

Virtual Reality Attention Management

University of California, Davis

NCT03221244

RECRUITING Phase 4 44 participants

Stimulant vs. Non-stimulant Treatments and Reward Processing in Drug-naive Youth at SUD Risk

Icahn School of Medicine at Mount Sinai

NCT03781765

RECRUITING Phase 1 42 participants

A Trial to Assess How Centanafadine Interacts With Stimulants in the Body

Otsuka Pharmaceutical Development & Commercialization

NCT07314333

RECRUITING NA 36 participants

Comparative Efficacy of Organizational Skills Training (OST) and Mindfulness-Based Intervention (MBI)

Seattle Children's Hospital

NCT07281092

RECRUITING NA 36 participants

A Pilot Study of a Remote ADHD Monitoring Program

IDeA States Pediatric Clinical Trials Network

NCT06743425

RECRUITING NA 30 participants

Comparative Efficacy of Organizational Skills Training (OST) and Mindfulness-Based Intervention (MBI)

Duke University

NCT07089745

RECRUITING 21 participants

Impact of Sulphonylureas on Neurodevelopmental Outcomes in KCNJ11-related Intermediate Developmental Delay, Epilepsy and Neonatal Diabetes (iDEND) Syndrome

Royal Devon and Exeter NHS Foundation Trust

NCT05751525

RECRUITING NA 10 participants

Moms Managing Attention-Deficit/Hyperactivity Disorder (ADHD) Study

University of Pittsburgh

NCT06540547

ACTIVE NOT RECRUITING NA 300 participants

Reducing Disparities in Behavioral Health Treatment for Children in Primary Care

Children's Hospital of Philadelphia

NCT04082234

ACTIVE NOT RECRUITING Phase 4 288 participants

Single and Combined Effects of Behavioral, Academic, and Medication Treatments for ADHD in the Classroom

Florida International University

NCT05469386

ACTIVE NOT RECRUITING Phase 3 240 participants

Treating Parents with ADHD and Their Young Children Via Telehealth: a Hybrid Type I Effectiveness-Implementation Trial

University of Maryland, College Park

NCT04240756

ACTIVE NOT RECRUITING 198 participants

EndeavorOTC™ Prospective Product Registry

Akili Interactive Labs

NCT06109051

ACTIVE NOT RECRUITING NA 194 participants

An Adjunct Study to Assess Guided ADHD Therapy for Managing the Extent and Severity of Symptoms

Lumos Labs

NCT05805176

ACTIVE NOT RECRUITING 150 participants

EndeavorRx® Prospective Product Registry ("Expedition EndeavorRx")

Akili Interactive Labs

NCT05991167

ACTIVE NOT RECRUITING NA 146 participants

tRNS Treatment for ADHD Symptoms

Innosphere

NCT06189703

ACTIVE NOT RECRUITING NA 120 participants

Evaluating Stress Management Strategies Within the School Readiness Parenting Program

Florida International University

NCT06626750

ACTIVE NOT RECRUITING NA 106 participants

Testing "SupporT for ADHD and Related Treatment" (START) for Families of Children With ADHD

Ann & Robert H Lurie Children's Hospital of Chicago

NCT05796427

ACTIVE NOT RECRUITING NA 25 participants

A Trial of Two-Week Brain Stimulation for Teenagers With ADHD

Bradley Hospital

NCT05102864

ACTIVE NOT RECRUITING NA 6 participants

Flashed Light Therapy for Adolescents With ADHD and Delayed Sleep Timing

University of California, Los Angeles

NCT06036420

COMPLETED 4,193 participants

National Child Traumatic Stress Network (NCTSN) Quality Improvement Initiative Database

Hugo W. Moser Research Institute at Kennedy Krieger

NCT01591694

COMPLETED Phase 4 577 participants

Evaluation of an Intervention for Improving Community-based Pediatric Attention-Deficit Hyperactivity Disorder (ADHD) Care

Children's Hospital Medical Center, Cincinnati

NCT01143701

COMPLETED NA 560 participants

Guided ADHD Therapy for Managing the Extent and Severity of Symptoms

Lumos Labs

NCT05296473

COMPLETED Phase 2 370 participants

Dose-Finding Study to Evaluate the Efficacy and Safety of Modafinil as Treatment for Adults With ADHD

Cephalon

NCT00315276

COMPLETED Phase 3 360 participants

PRC-063 in Adolescent ADHD

Rhodes Pharmaceuticals, L.P.

NCT02139111

COMPLETED 312 participants

Adolescent Changes in Brain and Behavior in Boys and Girls With ADHD

Hugo W. Moser Research Institute at Kennedy Krieger

NCT05927506

COMPLETED Phase 4 297 participants

A Double-Blind Comparison of Concerta and Placebo in Adults With Attention Deficit Hyperactivity Disorder

Massachusetts General Hospital

NCT00181571

COMPLETED Phase 2 295 participants

A Study of TD-9855 in Adults With Attention-Deficit/Hyperactivity Disorder (ADHD)

Theravance Biopharma

NCT01458340

COMPLETED Phase 3 288 participants

PRC-063 Adult Laboratory Classroom Study in Adults With Attention-Deficit/Hyperactivity Disorder (ADHD)

Purdue Pharma, Canada

NCT03618030

COMPLETED Phase 3 255 participants

Smoking Cessation for Adults With Attention Deficit Hyperactivity Disorder (ADHD)

University of Cincinnati

NCT00253747

COMPLETED NA 251 participants

Central Executive Training (CET) for ADHD

Florida State University

NCT03324464

COMPLETED Phase 3 230 participants

Efficacy and Safety of Methylphenidate HCl ER Capsules in Children and Adolescents With ADHD

Rhodes Pharmaceuticals, L.P.

NCT01239030

COMPLETED Phase 3 217 participants

Evaluate the Efficacy &Safety of Methylphenidate Transdermal System (MTS) in Adolescents Aged 13-17 Years With ADHD

Noven Therapeutics

NCT00499863

COMPLETED Phase 3 156 participants

PRC-063 Classroom Study in Children (6-12 Years of Age) With ADHD

Purdue Pharma, Canada

NCT03172481

COMPLETED Phase 2 115 participants

Treatment of Adult Attention Deficit Hyperactivity Disorder (ADHD) in Methadone Patients - 1

New York State Psychiatric Institute

NCT00061087

COMPLETED 106 participants

Behavioral Effects of Obstructive Sleep Apnea in Children

University of Michigan

NCT00060723

COMPLETED Phase 3 90 participants

Safety and Efficacy Study of Dexmethylphenidate in Children With ADHD

Novartis

NCT00141063

COMPLETED NA 72 participants

A Peer-Delivered High School Preparatory Intervention for Students With ADHD

Seattle Children's Hospital

NCT04571320

COMPLETED NA 69 participants

Effects of Performing Arts on Attention-deficit/Hyperactivity Disorder (ADHD)

Virginia Polytechnic Institute and State University

NCT07318935

COMPLETED NA 65 participants

A Novel fNIRS Neurofeedback Intervention for Enhancement of Working Memory in Attention Deficit Hyperactivity Disorder (ADHD)

Stanford University

NCT04002167

COMPLETED NA 59 participants

Brain Plasticity Underlying Acquisition of New Organizational Skills in Children

NYU Langone Health

NCT04108273

COMPLETED NA 59 participants

Tai Chi Training for Children With ADHD

Hugo W. Moser Research Institute at Kennedy Krieger

NCT02234557

COMPLETED Phase 4 48 participants

Basic and Clinical Research on Attention Deficit Hyperactivity Disorder (ADHD)

University of Illinois at Chicago

NCT00663442

COMPLETED 48 participants

Initial Validation of the Vanderbilt ADHD Measure for Adolescent Patients in the ICISS Project

Boston Children's Hospital

NCT01964209

COMPLETED NA 42 participants

Brain Plasticity Underlying Acquisition of New Organizational Skills in Children-R61 Phase

NYU Langone Health

NCT03148782

COMPLETED Phase 4 38 participants

Does Pharmacological Treatment of Attention Deficit Hyperactivity Disorder (ADHD) in Adults Enhance Parenting Performance?

Florida International University

NCT01127607

COMPLETED NA 36 participants

Effects of Noise Cancelling Headphones on Neurocognitive and Academic Outcomes in ADHD

Duke University

NCT03216512

COMPLETED Phase 4 36 participants

Study of Medication Patch to Treat Children Ages 6-12 With ADHD

Massachusetts General Hospital

NCT00586157

COMPLETED NA 35 participants

Pediatric Aquatic Occupational Therapy for Children With Sensory Processing Challenges

Kristen Pataki

NCT06484946

COMPLETED NA 32 participants

El Faro: Addressing Mental Health Inequities Among Latinx Children With ADHD in Durham

Duke University

NCT05928182

COMPLETED Phase 1 31 participants

Safety, Tolerability, PK & Efficacy of V81444 in Volunteers With Attention Deficit/ Hyperactivity Disorder (ADHD)

Vernalis (R&D)

NCT02253745

COMPLETED NA 29 participants

Study of the Effect of Calorie Supplementation on Growth in Young Children on ADHD Medication

University of Nebraska

NCT00561340

COMPLETED NA 28 participants

Effects of Exercise Intensity on ADHD Symptoms

Kent State University

NCT06753253

COMPLETED Phase 1 27 participants

The Reinforcing Mechanisms of Smoking in Adult ADHD

University of California, Irvine

NCT00573859

COMPLETED NA 26 participants

Effects of Cognitive Training on Academic Task Performance in Attention Deficit Hyperactivity Disorder (ADHD)

University of California, Davis

NCT01124721

COMPLETED Phase 1 24 participants

Vitamin D as a Therapeutic Adjunct in the Stimulant Treatment of ADHD

Yale University

NCT03103750

COMPLETED NA 20 participants

ACTIVATE: A Computerized Training Program for Children With ADHD

New York University

NCT02562469

COMPLETED Early Phase 1 20 participants

Validating a New Non-invasive Approach to Testing Lidocaine Effectiveness

PhenoSolve

NCT03680885

COMPLETED NA 14 participants

Treating Sleep in Teens With ADHD

Children's Hospital Medical Center, Cincinnati

NCT04270812

COMPLETED NA 7 participants

Improving Behavioral Health Care for Children With ADHD

NYU Langone Health

NCT02972086

COMPLETED Phase 1 6 participants

TD-9855 Mass Balance Study

Theravance Biopharma

NCT01924143

COMPLETED Phase 3

Study to Assess Satisfaction With Modafinil Treatment in Children and Adolescents With ADHD

Cephalon

NCT00228540

Phase Distribution

PhaseTrial count
Early Phase 1 6
Phase 2 3
Phase 3 10
Phase 4 10

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the ADHD Trial Landscape

ClinicalTrials.gov lists 76 US studies indexed under ADHD, and 23 of those are currently open to recruitment — roughly 30% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for ADHD shows 20 late-stage studies (Phase 3 and Phase 4 combined) alongside 9 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for ADHD is led by Duke University with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 76 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for ADHD?

PlainTrial tracks 76 US clinical trials for ADHD, of which 23 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for ADHD?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →