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ADHD
Open-data reference.
76 US clinical trials · 23 currently recruiting
Active & Recent Trials
Carboxylesterase 1 Genetic Variation and Methylphenidate in ADHD
Icahn School of Medicine at Mount Sinai
NCT03781752
AWARE: Management of ADHD in Autism Spectrum Disorder
Daniel Coury
NCT05916339
P3b Short-term Study of CTN in Patients With ADHD and Comorbid Anxiety
Otsuka Pharmaceutical Development & Commercialization
NCT06973577
Advancing Identification of Circadian Delay in ADHD Youth: Associations With Clinical Heterogeneity and Cognition
Duke University
NCT06971640
Central Executive Training and Parent Training for ADHD
Florida State University
NCT05492422
Target ADHD Executive Working Memory Replication Study
Hartford Hospital
NCT06446284
A Comparative Study to Evaluate a Novel Algorithm As a Diagnostic Aid for ADHD in Youth Ages 6-17.
MindTension
NCT06728969
Fidgeting and Attentional and Emotional Regulation in ADHD
University of California, Davis
NCT04526600
Evaluating Treatment of ADHD in Children with Down Syndrome
Children's Hospital Medical Center, Cincinnati
NCT04219280
A Study to Evaluate the Effects of a Supplement on the Side Effects Associated With Stimulant Medications
Outliers
NCT07380412
Impact of Parental Emotion Regulation on the Treatment of ADHD
Milton S. Hershey Medical Center
NCT05299814
Digital Health Intervention for Children With ADHD
University of California, Riverside
NCT06456372
Rural Autistic Individuals - Supporting Expression
Montana State University
NCT07054866
Accelerated iTBS Targeting of Working Memory Versus Inhibitory Control in Adolescent ADHD
Bradley Hospital
NCT07219810
Evaluate the Effects of Long-term Use of Psychotropic Medications on Eye Movement Patterns With the Gaize Device
Gaize
NCT07389473
Virtual Reality Attention Management
University of California, Davis
NCT03221244
Stimulant vs. Non-stimulant Treatments and Reward Processing in Drug-naive Youth at SUD Risk
Icahn School of Medicine at Mount Sinai
NCT03781765
A Trial to Assess How Centanafadine Interacts With Stimulants in the Body
Otsuka Pharmaceutical Development & Commercialization
NCT07314333
Comparative Efficacy of Organizational Skills Training (OST) and Mindfulness-Based Intervention (MBI)
Seattle Children's Hospital
NCT07281092
A Pilot Study of a Remote ADHD Monitoring Program
IDeA States Pediatric Clinical Trials Network
NCT06743425
Comparative Efficacy of Organizational Skills Training (OST) and Mindfulness-Based Intervention (MBI)
Duke University
NCT07089745
Impact of Sulphonylureas on Neurodevelopmental Outcomes in KCNJ11-related Intermediate Developmental Delay, Epilepsy and Neonatal Diabetes (iDEND) Syndrome
Royal Devon and Exeter NHS Foundation Trust
NCT05751525
Moms Managing Attention-Deficit/Hyperactivity Disorder (ADHD) Study
University of Pittsburgh
NCT06540547
Reducing Disparities in Behavioral Health Treatment for Children in Primary Care
Children's Hospital of Philadelphia
NCT04082234
Single and Combined Effects of Behavioral, Academic, and Medication Treatments for ADHD in the Classroom
Florida International University
NCT05469386
Treating Parents with ADHD and Their Young Children Via Telehealth: a Hybrid Type I Effectiveness-Implementation Trial
University of Maryland, College Park
NCT04240756
EndeavorOTC™ Prospective Product Registry
Akili Interactive Labs
NCT06109051
An Adjunct Study to Assess Guided ADHD Therapy for Managing the Extent and Severity of Symptoms
Lumos Labs
NCT05805176
EndeavorRx® Prospective Product Registry ("Expedition EndeavorRx")
Akili Interactive Labs
NCT05991167
tRNS Treatment for ADHD Symptoms
Innosphere
NCT06189703
Evaluating Stress Management Strategies Within the School Readiness Parenting Program
Florida International University
NCT06626750
Testing "SupporT for ADHD and Related Treatment" (START) for Families of Children With ADHD
Ann & Robert H Lurie Children's Hospital of Chicago
NCT05796427
A Trial of Two-Week Brain Stimulation for Teenagers With ADHD
Bradley Hospital
NCT05102864
Flashed Light Therapy for Adolescents With ADHD and Delayed Sleep Timing
University of California, Los Angeles
NCT06036420
National Child Traumatic Stress Network (NCTSN) Quality Improvement Initiative Database
Hugo W. Moser Research Institute at Kennedy Krieger
NCT01591694
Evaluation of an Intervention for Improving Community-based Pediatric Attention-Deficit Hyperactivity Disorder (ADHD) Care
Children's Hospital Medical Center, Cincinnati
NCT01143701
Guided ADHD Therapy for Managing the Extent and Severity of Symptoms
Lumos Labs
NCT05296473
Dose-Finding Study to Evaluate the Efficacy and Safety of Modafinil as Treatment for Adults With ADHD
Cephalon
NCT00315276
PRC-063 in Adolescent ADHD
Rhodes Pharmaceuticals, L.P.
NCT02139111
Adolescent Changes in Brain and Behavior in Boys and Girls With ADHD
Hugo W. Moser Research Institute at Kennedy Krieger
NCT05927506
A Double-Blind Comparison of Concerta and Placebo in Adults With Attention Deficit Hyperactivity Disorder
Massachusetts General Hospital
NCT00181571
A Study of TD-9855 in Adults With Attention-Deficit/Hyperactivity Disorder (ADHD)
Theravance Biopharma
NCT01458340
PRC-063 Adult Laboratory Classroom Study in Adults With Attention-Deficit/Hyperactivity Disorder (ADHD)
Purdue Pharma, Canada
NCT03618030
Smoking Cessation for Adults With Attention Deficit Hyperactivity Disorder (ADHD)
University of Cincinnati
NCT00253747
Central Executive Training (CET) for ADHD
Florida State University
NCT03324464
Efficacy and Safety of Methylphenidate HCl ER Capsules in Children and Adolescents With ADHD
Rhodes Pharmaceuticals, L.P.
NCT01239030
Evaluate the Efficacy &Safety of Methylphenidate Transdermal System (MTS) in Adolescents Aged 13-17 Years With ADHD
Noven Therapeutics
NCT00499863
PRC-063 Classroom Study in Children (6-12 Years of Age) With ADHD
Purdue Pharma, Canada
NCT03172481
Treatment of Adult Attention Deficit Hyperactivity Disorder (ADHD) in Methadone Patients - 1
New York State Psychiatric Institute
NCT00061087
Behavioral Effects of Obstructive Sleep Apnea in Children
University of Michigan
NCT00060723
Safety and Efficacy Study of Dexmethylphenidate in Children With ADHD
Novartis
NCT00141063
A Peer-Delivered High School Preparatory Intervention for Students With ADHD
Seattle Children's Hospital
NCT04571320
Effects of Performing Arts on Attention-deficit/Hyperactivity Disorder (ADHD)
Virginia Polytechnic Institute and State University
NCT07318935
A Novel fNIRS Neurofeedback Intervention for Enhancement of Working Memory in Attention Deficit Hyperactivity Disorder (ADHD)
Stanford University
NCT04002167
Brain Plasticity Underlying Acquisition of New Organizational Skills in Children
NYU Langone Health
NCT04108273
Tai Chi Training for Children With ADHD
Hugo W. Moser Research Institute at Kennedy Krieger
NCT02234557
Basic and Clinical Research on Attention Deficit Hyperactivity Disorder (ADHD)
University of Illinois at Chicago
NCT00663442
Initial Validation of the Vanderbilt ADHD Measure for Adolescent Patients in the ICISS Project
Boston Children's Hospital
NCT01964209
Brain Plasticity Underlying Acquisition of New Organizational Skills in Children-R61 Phase
NYU Langone Health
NCT03148782
Does Pharmacological Treatment of Attention Deficit Hyperactivity Disorder (ADHD) in Adults Enhance Parenting Performance?
Florida International University
NCT01127607
Effects of Noise Cancelling Headphones on Neurocognitive and Academic Outcomes in ADHD
Duke University
NCT03216512
Study of Medication Patch to Treat Children Ages 6-12 With ADHD
Massachusetts General Hospital
NCT00586157
Pediatric Aquatic Occupational Therapy for Children With Sensory Processing Challenges
Kristen Pataki
NCT06484946
El Faro: Addressing Mental Health Inequities Among Latinx Children With ADHD in Durham
Duke University
NCT05928182
Safety, Tolerability, PK & Efficacy of V81444 in Volunteers With Attention Deficit/ Hyperactivity Disorder (ADHD)
Vernalis (R&D)
NCT02253745
Study of the Effect of Calorie Supplementation on Growth in Young Children on ADHD Medication
University of Nebraska
NCT00561340
Effects of Exercise Intensity on ADHD Symptoms
Kent State University
NCT06753253
The Reinforcing Mechanisms of Smoking in Adult ADHD
University of California, Irvine
NCT00573859
Effects of Cognitive Training on Academic Task Performance in Attention Deficit Hyperactivity Disorder (ADHD)
University of California, Davis
NCT01124721
Vitamin D as a Therapeutic Adjunct in the Stimulant Treatment of ADHD
Yale University
NCT03103750
ACTIVATE: A Computerized Training Program for Children With ADHD
New York University
NCT02562469
Validating a New Non-invasive Approach to Testing Lidocaine Effectiveness
PhenoSolve
NCT03680885
Treating Sleep in Teens With ADHD
Children's Hospital Medical Center, Cincinnati
NCT04270812
Improving Behavioral Health Care for Children With ADHD
NYU Langone Health
NCT02972086
TD-9855 Mass Balance Study
Theravance Biopharma
NCT01924143
Study to Assess Satisfaction With Modafinil Treatment in Children and Adolescents With ADHD
Cephalon
NCT00228540
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 6 |
| Phase 2 | 3 |
| Phase 3 | 10 |
| Phase 4 | 10 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the ADHD Trial Landscape
ClinicalTrials.gov lists 76 US studies indexed under ADHD, and 23 of those are currently open to recruitment — roughly 30% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for ADHD shows 20 late-stage studies (Phase 3 and Phase 4 combined) alongside 9 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for ADHD is led by Duke University with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 76 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for ADHD?
PlainTrial tracks 76 US clinical trials for ADHD, of which 23 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for ADHD?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.