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ClinicalTrials.gov 26 recruiting now early-phase tilt

Fibromyalgia: early-phase trial registry

26 of 77 indexed Fibromyalgia trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #175 of 28,707 conditions by registered trial count.

77 US clinical trials · 26 currently recruiting · #175 of 28,707 conditions by registered trial count

Fibromyalgia: 77 US clinical trials tracked, 26 recruiting.

Fibromyalgia is the subject of 77 registered US clinical trials on ClinicalTrials.gov, 26 of them currently open to new participants. 10 are in Phase 3-4 (later-stage) and 18 in Phase 1-2 (earlier-stage). The most active sponsor is University of Michigan, running 6 of these trials.

Enrollment posture brief

Registry condition fibromyalgia

OPEN 26 | RECR 34% | LATE 10 | EARLY 18 | RANK #175 | SPON 6

Nearest open-share peer: Breast Cancer (34% recruiting · 1,251 trials)

Acute Kidney Injury44%Tobacco Use42.9%Fibromyalgia (this)34%ADHD31.2%Age-related Macular Degenera26.7%
Open-enrollment share among volume-matched conditions near Fibromyalgia

Fibromyalgia lists 26 open slots (34% of 77 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Fibromyalgia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Fibromyalgia is recruiting below its size-band peers.

    26 of 77 indexed trials (33.8%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Fibromyalgia trials is spread across many organizations.

    University of Michigan accounts for 6 of 77 trials (7.8%). 53 distinct sponsors appear on at least one study for this condition label.

  3. Typical Fibromyalgia enrolment sits around 66 participants.

    Median target enrolment is 66 among the 77 trials that report a genuine target (sentinel values excluded). 44 of those (57.1%) plan for fewer than 100 participants.

  4. Fibromyalgia research is mostly interventional.

    68 interventional and 9 observational studies make up this index (88.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 16Phase 212Phase 36Phase 44

Open and recent trials

77 total, page 2 of 2

COMPLETED Phase 2 89 participants

A Study To Assess Esreboxetine's Effect On Concentration, Memory, Decision Making And Problem Solving In Patients With Fibromyalgia.

Pfizer

NCT00752505

COMPLETED NA 80 participants

Mechanisms of Affective Touch in Chronic Pain

Laura Case

NCT04206397

COMPLETED NA 66 participants

Healing Through Affective Self-Awareness in Fibromyalgia: a Randomized Controlled Trial

Mike Hsu

NCT00437411

COMPLETED NA 66 participants

Tai Chi Mind-Body Therapy for Fibromyalgia

Tufts Medical Center

NCT00515008

COMPLETED Phase 2 61 participants

Heart Rate Variability in Response to Metformin Challenge

Woodinville Psychiatric Associates

NCT02500628

COMPLETED NA 60 participants

Prospective Study to Evaluate a Digital Regimen for Fibromyalgia Management: An Extension Study

Swing Therapeutics

NCT05433337

COMPLETED NA 57 participants

Cranial Electrical Stimulation Effects on Symptoms in Persons With Fibromyalgia

University of Virginia

NCT00928720

COMPLETED NA 55 participants

Making Better Lives: Patient-Focused Care for Low Back Pain (LBP)

VA Office of Research and Development

NCT02697435

COMPLETED Phase 3 51 participants

Novel Use of (Oral) Ketotifen for the Treatment of Fibromyalgia: A Pilot Study

Indiana University

NCT01553318

COMPLETED Phase 2 45 participants

The Exercise Response to Pharmacologic Cholinergic Stimulation in Myalgic Encephalomyelitis / Chronic Fatigue Syndrome

Brigham and Women's Hospital

NCT03674541

COMPLETED Phase 4 42 participants

Quetiapine Compared With Placebo in the Management of Fibromyalgia

East Tennessee State University

NCT01458964

COMPLETED Phase 1 40 participants

Intravenous Micronutrient Therapy (IVMT) for Fibromyalgia

National Center for Complementary and Integrative Health (NCCIH)

NCT00067405

COMPLETED Phase 2 37 participants

The Effect of Milnacipran in Patients With Fibromyalgia

Beth Israel Medical Center

NCT01108731

COMPLETED NA 34 participants

Pain Rehabilitation Virtual Reality (PRVR): Innovations to Enhance Mobility in the Presence of Pain

Stanford University

NCT04636177

COMPLETED Phase 4 30 participants

A Pilot Study on the Use of Nociceptive Flexion Reflex for Fibromyalgia

Indiana University

NCT00965601

COMPLETED NA 30 participants

Generalized Hypersensitivity in Patients With Fibromyalgia Syndrome

University of Florida

NCT04415866

COMPLETED Phase 2 27 participants

Dextromethorphan in Fibromyalgia

University of Alabama at Birmingham

NCT03538054

COMPLETED NA 24 participants

Effect of Repetitive Transcranial Direct Current Stimulation (tDCS) on Chronic Pelvic Pain

Summa Health System

NCT00554320

COMPLETED 24 participants

Effect of Temperature on Pain and Brown Adipose Activity in Fibromyalgia

University of Minnesota

NCT01322425

COMPLETED NA 23 participants

Prospective Evaluation of Reduced Impedance Noninvasive Cortical Electrostimulation (RINCE) to Reduce Fibromyalgia Effects - Extension Study

Cerephex Corporation

NCT01958853

COMPLETED Phase 4 19 participants

The Effects of Milnacipran on Sleep Disturbance in Fibromyalgia

Mansoor Ahmed M.D.

NCT01234675

COMPLETED Phase 2 19 participants

Transcranial Magnetic Stimulation for Treating Women With Chronic Widespread Pain

University of Washington

NCT00524420

COMPLETED NA 12 participants

Veteran Ear Acupuncture Pilot Project

Chillicothe VA Medical Center

NCT04208659

COMPLETED NA 11 participants

Remote Gamified Sensory Perceptual Training for Patients With Fibromyalgia: a Feasibility Trial

Icahn School of Medicine at Mount Sinai

NCT04919525

COMPLETED Phase 4 8 participants

Effect of Milnacipran on Pain in Fibromyalgia

University of California, San Diego

NCT01288807

COMPLETED Phase 1 6 participants

TD-9855 Mass Balance Study

Theravance Biopharma

NCT01924143

COMPLETED Phase 3 6 participants

Safety and Efficacy of Fluoxetine in Juvenile Fibromyalgia

University of Cincinnati

NCT00115804

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Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 12
Phase 3 6
Phase 4 4

Named interventions

Most-linked intervention names on Fibromyalgia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
8 trials
Cognitive Behavioral Therapy Behavioral
3 trials
Milnacipran Drug
2 trials
affective touch Behavioral
1 trials
Self-administration of auricular acupuncture with prosthesis Procedure
1 trials
Self-administration of auricular acupuncture without prosthesis Procedure
1 trials
Recovery Factors Dietary supplement
1 trials
sham device Device
1 trials

US sites by state

Facility locations filed on Fibromyalgia trials. A trial with sites in several states counts in each.

California 12 trials
Ohio 10 trials
Florida 10 trials
Michigan 9 trials
Massachusetts 9 trials
New York 5 trials
North Carolina 5 trials
Georgia 5 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Fibromyalgia page

77 registered trials, 26 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Fibromyalgia condition card totals 77 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.