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ClinicalTrials.gov 26 recruiting now official registry

Fibromyalgia clinical trials

26 of 77 indexed Fibromyalgia trials are currently recruiting.

77 US clinical trials · 26 currently recruiting

Fibromyalgia is the subject of 77 registered US clinical trials on ClinicalTrials.gov, 26 of them currently open to new participants. 10 are in Phase 3-4 (later-stage) and 18 in Phase 1-2 (earlier-stage). The most active sponsor is University of Michigan, running 6 of these trials.

The research picture

Fibromyalgia has 77 registered US clinical trials, 26 of them open to new participants right now, about 34% of the total.

26
recruiting participants now
34%
of trials open to enrollment
10
in Phase 3–4 (later-stage)
6
top sponsor: University of Michigan
Phase 16Phase 212Phase 36Phase 44

Active & Recent Trials

77 total, page 2 of 2

COMPLETED Phase 2 89 participants

A Study To Assess Esreboxetine's Effect On Concentration, Memory, Decision Making And Problem Solving In Patients With Fibromyalgia.

Pfizer

NCT00752505

COMPLETED NA 80 participants

Mechanisms of Affective Touch in Chronic Pain

Laura Case

NCT04206397

COMPLETED NA 66 participants

Healing Through Affective Self-Awareness in Fibromyalgia: a Randomized Controlled Trial

Mike Hsu

NCT00437411

COMPLETED NA 66 participants

Tai Chi Mind-Body Therapy for Fibromyalgia

Tufts Medical Center

NCT00515008

COMPLETED Phase 2 61 participants

Heart Rate Variability in Response to Metformin Challenge

Woodinville Psychiatric Associates

NCT02500628

COMPLETED NA 60 participants

Prospective Study to Evaluate a Digital Regimen for Fibromyalgia Management: An Extension Study

Swing Therapeutics

NCT05433337

COMPLETED NA 57 participants

Cranial Electrical Stimulation Effects on Symptoms in Persons With Fibromyalgia

University of Virginia

NCT00928720

COMPLETED NA 55 participants

Making Better Lives: Patient-Focused Care for Low Back Pain (LBP)

VA Office of Research and Development

NCT02697435

COMPLETED Phase 3 51 participants

Novel Use of (Oral) Ketotifen for the Treatment of Fibromyalgia: A Pilot Study

Indiana University

NCT01553318

COMPLETED Phase 2 45 participants

The Exercise Response to Pharmacologic Cholinergic Stimulation in Myalgic Encephalomyelitis / Chronic Fatigue Syndrome

Brigham and Women's Hospital

NCT03674541

COMPLETED Phase 4 42 participants

Quetiapine Compared With Placebo in the Management of Fibromyalgia

East Tennessee State University

NCT01458964

COMPLETED Phase 1 40 participants

Intravenous Micronutrient Therapy (IVMT) for Fibromyalgia

National Center for Complementary and Integrative Health (NCCIH)

NCT00067405

COMPLETED Phase 2 37 participants

The Effect of Milnacipran in Patients With Fibromyalgia

Beth Israel Medical Center

NCT01108731

COMPLETED NA 34 participants

Pain Rehabilitation Virtual Reality (PRVR): Innovations to Enhance Mobility in the Presence of Pain

Stanford University

NCT04636177

COMPLETED Phase 4 30 participants

A Pilot Study on the Use of Nociceptive Flexion Reflex for Fibromyalgia

Indiana University

NCT00965601

COMPLETED NA 30 participants

Generalized Hypersensitivity in Patients With Fibromyalgia Syndrome

University of Florida

NCT04415866

COMPLETED Phase 2 27 participants

Dextromethorphan in Fibromyalgia

University of Alabama at Birmingham

NCT03538054

COMPLETED NA 24 participants

Effect of Repetitive Transcranial Direct Current Stimulation (tDCS) on Chronic Pelvic Pain

Summa Health System

NCT00554320

COMPLETED 24 participants

Effect of Temperature on Pain and Brown Adipose Activity in Fibromyalgia

University of Minnesota

NCT01322425

COMPLETED NA 23 participants

Prospective Evaluation of Reduced Impedance Noninvasive Cortical Electrostimulation (RINCE) to Reduce Fibromyalgia Effects - Extension Study

Cerephex Corporation

NCT01958853

COMPLETED Phase 4 19 participants

The Effects of Milnacipran on Sleep Disturbance in Fibromyalgia

Mansoor Ahmed M.D.

NCT01234675

COMPLETED Phase 2 19 participants

Transcranial Magnetic Stimulation for Treating Women With Chronic Widespread Pain

University of Washington

NCT00524420

COMPLETED NA 12 participants

Veteran Ear Acupuncture Pilot Project

Chillicothe VA Medical Center

NCT04208659

COMPLETED NA 11 participants

Remote Gamified Sensory Perceptual Training for Patients With Fibromyalgia: a Feasibility Trial

Icahn School of Medicine at Mount Sinai

NCT04919525

COMPLETED Phase 4 8 participants

Effect of Milnacipran on Pain in Fibromyalgia

University of California, San Diego

NCT01288807

COMPLETED Phase 1 6 participants

TD-9855 Mass Balance Study

Theravance Biopharma

NCT01924143

COMPLETED Phase 3 6 participants

Safety and Efficacy of Fluoxetine in Juvenile Fibromyalgia

University of Cincinnati

NCT00115804

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Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 12
Phase 3 6
Phase 4 4

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Fibromyalgia Trial Landscape

77 indexed Fibromyalgia studies · 26 recruiting (34%).

Phase mix: 10 late (III/IV) vs 18 early (I/II).

Top sponsor: University of Michigan (6 trials), 9 others listed. 27 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Fibromyalgia?

PlainTrial tracks 77 US clinical trials for Fibromyalgia, of which 26 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Fibromyalgia?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.