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Fibromyalgia clinical trials
26 of 77 indexed Fibromyalgia trials are currently recruiting.
77 US clinical trials · 26 currently recruiting
Fibromyalgia is the subject of 77 registered US clinical trials on ClinicalTrials.gov, 26 of them currently open to new participants. 10 are in Phase 3-4 (later-stage) and 18 in Phase 1-2 (earlier-stage). The most active sponsor is University of Michigan, running 6 of these trials.
The research picture
Fibromyalgia has 77 registered US clinical trials, 26 of them open to new participants right now, about 34% of the total.
- 26
- recruiting participants now
- 34%
- of trials open to enrollment
- 10
- in Phase 3–4 (later-stage)
- 6
- top sponsor: University of Michigan
Active & Recent Trials
77 total, page 2 of 2
A Study To Assess Esreboxetine's Effect On Concentration, Memory, Decision Making And Problem Solving In Patients With Fibromyalgia.
Pfizer
NCT00752505
Mechanisms of Affective Touch in Chronic Pain
Laura Case
NCT04206397
Healing Through Affective Self-Awareness in Fibromyalgia: a Randomized Controlled Trial
Mike Hsu
NCT00437411
Tai Chi Mind-Body Therapy for Fibromyalgia
Tufts Medical Center
NCT00515008
Heart Rate Variability in Response to Metformin Challenge
Woodinville Psychiatric Associates
NCT02500628
Prospective Study to Evaluate a Digital Regimen for Fibromyalgia Management: An Extension Study
Swing Therapeutics
NCT05433337
Cranial Electrical Stimulation Effects on Symptoms in Persons With Fibromyalgia
University of Virginia
NCT00928720
Making Better Lives: Patient-Focused Care for Low Back Pain (LBP)
VA Office of Research and Development
NCT02697435
Novel Use of (Oral) Ketotifen for the Treatment of Fibromyalgia: A Pilot Study
Indiana University
NCT01553318
The Exercise Response to Pharmacologic Cholinergic Stimulation in Myalgic Encephalomyelitis / Chronic Fatigue Syndrome
Brigham and Women's Hospital
NCT03674541
Quetiapine Compared With Placebo in the Management of Fibromyalgia
East Tennessee State University
NCT01458964
Intravenous Micronutrient Therapy (IVMT) for Fibromyalgia
National Center for Complementary and Integrative Health (NCCIH)
NCT00067405
The Effect of Milnacipran in Patients With Fibromyalgia
Beth Israel Medical Center
NCT01108731
Pain Rehabilitation Virtual Reality (PRVR): Innovations to Enhance Mobility in the Presence of Pain
Stanford University
NCT04636177
A Pilot Study on the Use of Nociceptive Flexion Reflex for Fibromyalgia
Indiana University
NCT00965601
Generalized Hypersensitivity in Patients With Fibromyalgia Syndrome
University of Florida
NCT04415866
Dextromethorphan in Fibromyalgia
University of Alabama at Birmingham
NCT03538054
Effect of Repetitive Transcranial Direct Current Stimulation (tDCS) on Chronic Pelvic Pain
Summa Health System
NCT00554320
Effect of Temperature on Pain and Brown Adipose Activity in Fibromyalgia
University of Minnesota
NCT01322425
Prospective Evaluation of Reduced Impedance Noninvasive Cortical Electrostimulation (RINCE) to Reduce Fibromyalgia Effects - Extension Study
Cerephex Corporation
NCT01958853
The Effects of Milnacipran on Sleep Disturbance in Fibromyalgia
Mansoor Ahmed M.D.
NCT01234675
Transcranial Magnetic Stimulation for Treating Women With Chronic Widespread Pain
University of Washington
NCT00524420
Veteran Ear Acupuncture Pilot Project
Chillicothe VA Medical Center
NCT04208659
Remote Gamified Sensory Perceptual Training for Patients With Fibromyalgia: a Feasibility Trial
Icahn School of Medicine at Mount Sinai
NCT04919525
Effect of Milnacipran on Pain in Fibromyalgia
University of California, San Diego
NCT01288807
TD-9855 Mass Balance Study
Theravance Biopharma
NCT01924143
Safety and Efficacy of Fluoxetine in Juvenile Fibromyalgia
University of Cincinnati
NCT00115804
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 6 |
| Phase 2 | 12 |
| Phase 3 | 6 |
| Phase 4 | 4 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Fibromyalgia Trial Landscape
77 indexed Fibromyalgia studies · 26 recruiting (34%).
Phase mix: 10 late (III/IV) vs 18 early (I/II).
Top sponsor: University of Michigan (6 trials), 9 others listed. 27 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Fibromyalgia?
PlainTrial tracks 77 US clinical trials for Fibromyalgia, of which 26 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Fibromyalgia?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.