Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT07226648 · ClinicalTrials.gov registry record · NA
Ultrasonic Neuromodulation of Cingulate Cortex for Fibromyalgia
A NA study of Fibromyalgia, sponsored by SPIRE Therapeutics.
- Recruiting
- Registry status
- NA
- Development phase
- 180
- Enrollment target
- 2
- Study locations
NCT07226648: Recruiting NA study of Fibromyalgia, sponsored by SPIRE Therapeutics.
NCT07226648 is a NA study of Fibromyalgia that is actively recruiting participants, run by SPIRE Therapeutics. The registered enrollment target is 180 participants, roughly in line with the 177-participant average among 76 other Fibromyalgia trials with a reported enrollment target. The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07226648, a NA study of Fibromyalgia, is actively recruiting participants, sponsored by SPIRE Therapeutics.
- RECRUITING
- Registry status
- NA
- Development phase
- 180 participants
- Enrollment target
- 2
- Study locations
Study Summary
The goal of this clinical trial is to evaluate a new noninvasive brain stimulation intervention for fibromyalgia and to determine its effectiveness in reducing pain. Participants will receive four treatments over the course of one month and will complete surveys at multiple time points throughout the 16-week study.
Primary Outcome
The NRS-11 is a scale from 0-10 with higher values representing higher levels of pain.
Conditions Studied
Interventions
- DEVICE Focused Ultrasound
Study Locations (2)
Minnesota
- University of Minnesota Medical Center Fairview - Minneapolis
Utah
- University of Utah - Salt Lake City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 180 participants |
| Start Date | 2025-12-11 |
| Est. Completion | 2026-12 |
| Phase | NA |
What NCT07226648 shows while recruiting
NCT07226648 is an interventional study that assigns participants to a tested intervention. The registered 180 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 177-participant average among 76 other Fibromyalgia trials with a reported enrollment target.
The record links to 1 condition, with Fibromyalgia appearing as the primary indexed condition, and to 1 intervention - of which Focused Ultrasound is the first listed.
NCT07226648 reports a single indexed study location in Minnesota, Utah.
Frequently Asked Questions
What is clinical trial NCT07226648 about?
NCT07226648 is a clinical study titled "Ultrasonic Neuromodulation of Cingulate Cortex for Fibromyalgia". The goal of this clinical trial is to evaluate a new noninvasive brain stimulation intervention for fibromyalgia and to determine its effectiveness in reducing pain. Participants will receive four treatments over the course of one month and will complete surveys at multiple time points throughout th...
What is the current status of trial NCT07226648?
This trial is currently recruiting. It is a NA study. The enrollment target is 180 participants. The study started on 2025-12-11. Estimated completion is 2026-12.
What conditions does trial NCT07226648 study?
This clinical trial studies the following conditions: Fibromyalgia.
What interventions are being tested in trial NCT07226648?
The interventions under investigation include: Focused Ultrasound (DEVICE).
Who is sponsoring clinical trial NCT07226648?
This trial is sponsored by SPIRE Therapeutics, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07226648 being conducted?
This trial has 2 study locations across Minnesota, Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Fibromyalgia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07226648's enrollment target sits among peer trials
180 20th of 76 higher than 57 of 76 other Fibromyalgia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Fibromyalgia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Auricular Neuromodulation in Veterans With Fibromyalgia
RECRUITING · NA
-
Effects of Breathing and Attention Training (BAT) on Pain Modulation
RECRUITING · NA
-
Neural Mechanisms of Light Driven Analgesia
RECRUITING · NA
-
Fibromyalgia Sleep A to ZZZ Study
RECRUITING · NA
-
Explosive Synchronization of Brain Network Activity in Chronic Pain
RECRUITING · NA
-
Brief Pain Exposure Therapy (BPET) For Nociplastic Pain
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01558804 · 180 participants
GRoup A StrePtococcus
- NCT02932176 · 180 participants
Machine Learning for Handheld Vascular Studies
- NCT03384563 · 180 participants · Phase 4
Effect of Dexmedetomidine on the Minimum Alveolar Concentration of Sevoflurane
- NCT03423628 · 180 participants · Phase 1
A Study to Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI