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NCT07245303 · ClinicalTrials.gov registry record · NA
Neural Mechanisms of Light Driven Analgesia
A NA study of Fibromyalgia and Musculoskeletal Pain, sponsored by University of North Carolina, Chapel Hill.
- Recruiting
- Registry status
- NA
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT07245303 is a NA study of Fibromyalgia and Musculoskeletal Pain that is actively recruiting participants, run by University of North Carolina, Chapel Hill. The registered enrollment target is 60 participants, below the 178-participant average among 76 other Fibromyalgia trials with a reported enrollment target (66% lower). The trial reports 1 study location across 1 state.
The verdict
NCT07245303, a NA study of Fibromyalgia and Musculoskeletal Pain, is actively recruiting participants, sponsored by University of North Carolina, Chapel Hill.
- RECRUITING
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this study will be to understand the biological mechanisms that are responsible to light-driven analgesia. Light presented to the retina has been shown to have pain relieving properties in pre-clinical and clinical studies. In this study the investigators will evaluate the functional connectivity between subcortical visual areas and non-image forming brain areas that are involved in pain sensation. The investigators will also evaluate how three colored light stimuli presented to the retina results in changes in whole brain evoked activation patterns in participants with chronic musculoskeletal pain and in healthy controls. The investigators will also assess while brain evoked activation patterns in response to a pressure pain stimulus in the presence of three light stimuli in individuals with chronic musculoskeletal pain and healthy controls.
Conditions Studied
Interventions
- OTHER S-cone modulating visual stimulus
- OTHER Equal Energy White Visual Stimulus
- OTHER Green light visual stimulus (S-OFF)
- OTHER Evoked Pressure Pain Stimulus
Study Locations (1)
North Carolina
- University of North Carolina at Chapel Hill - Chapel Hill
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2026-02-01 |
| Est. Completion | 2030-01-31 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07245303
The ClinicalTrials.gov registry entry for NCT07245303 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 178-participant average among 76 other Fibromyalgia trials with a reported enrollment target (66% lower). The listed sponsor is University of North Carolina, Chapel Hill, which has 1,109 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Fibromyalgia appearing as the primary indexed condition, and to 4 interventions - of which S-cone modulating visual stimulus is the first listed.
NCT07245303 reports 1 study location spanning 1 distinct geographic area - top geographies include North Carolina.
Frequently Asked Questions
What is clinical trial NCT07245303 about?
NCT07245303 is a clinical study titled "Neural Mechanisms of Light Driven Analgesia". The goal of this study will be to understand the biological mechanisms that are responsible to light-driven analgesia. Light presented to the retina has been shown to have pain relieving properties in pre-clinical and clinical studies. In this study the investigators will evaluate the functional con...
What is the current status of trial NCT07245303?
This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2026-02-01. Estimated completion is 2030-01-31.
What conditions does trial NCT07245303 study?
This clinical trial studies the following conditions: Fibromyalgia, Musculoskeletal Pain, Healthy Controls Group - Age and Sex-matched.
What interventions are being tested in trial NCT07245303?
The interventions under investigation include: S-cone modulating visual stimulus (OTHER), Equal Energy White Visual Stimulus (OTHER), Green light visual stimulus (S-OFF) (OTHER), Evoked Pressure Pain Stimulus (OTHER).
Who is sponsoring clinical trial NCT07245303?
This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07245303 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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