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NCT01757301 · ClinicalTrials.gov registry record · NA
Comprehensive vs. Assisted Management of Mood and Pain Symptoms
A NA study of Depression and Pain, sponsored by VA Office of Research and Development.
- Completed
- Registry status
- NA
- Development phase
- 296
- Enrollment target
- 1
- Study location
NCT01757301: Completed NA study of Depression and Pain, sponsored by VA Office of Research and Development.
NCT01757301 is a NA study of Depression and Pain that has completed, run by VA Office of Research and Development. The registered enrollment target is 296 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (62% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01757301, a NA study of Depression and Pain, has completed, sponsored by VA Office of Research and Development.
- COMPLETED
- Registry status
- NA
- Development phase
- 296 participants
- Enrollment target
- 1
- Study location
Study Summary
Pain is the most common presenting symptom in medical outpatients, and depression and anxiety are the two most common mental disorders. All three conditions are often inadequately treated and result in substantial disability, reduced health-related quality of life, and increased health care costs and utilization. Additionally, pain, anxiety, and depression (PAD) are frequently comorbid with one another and have reciprocal negative effects on treatment response and additive effects on adverse health outcomes. The PAD triad is especially burdensome in Veterans, with their high prevalence of chronic pain, depression, PTSD, and other anxiety disorders. The Comprehensive vs. Assisted Management of Mood and Physical Symptoms (CAMMPS) study is a randomized comparative effectiveness trial designed to test the relative effectiveness of a lower-resource vs. a higher-resource enhancement of usual primary care in the management of Veterans suffering from with pain plus comorbid anxiety and/or depression.
Primary Outcome
The primary outcome measure is the composite z-score of the main pain, anxiety, and depression measures in this trial: the BPI, GAD-7, PHQ-9, respectively. A standard z-score is calculated for each scale as follows: subject's scale score minus the sample mean divided by the sample standard deviation. A composite pain-anxiety-depression score is the average of the standard z-scores for the 3 scales. This is a scale of effect size where 0 represents no change from baseline, and a negative number m
Conditions Studied
Interventions
- OTHER Assisted Symptom Management (ASM)
- OTHER Comprehensive Symptom Management (CSM)
Study Locations (1)
Indiana
- Richard L. Roudebush VA Medical Center, Indianapolis, IN - Indianapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 296 participants |
| Start Date | 2014-01-02 |
| Est. Completion | 2017-11-30 |
| Phase | NA |
What the finished NCT01757301 record still lists
NCT01757301 is an interventional study that assigns participants to a tested intervention. The registered 296 participants enrollment target is mid-sized for trials with a published cap, below the 786-participant average among 679 other Depression trials with a reported enrollment target (62% lower).
The record links to 5 conditions, with Depression appearing as the primary indexed condition, and to 2 interventions - of which Assisted Symptom Management (ASM) is the first listed.
NCT01757301 reports a single indexed study location in Indiana.
Frequently Asked Questions
What is clinical trial NCT01757301 about?
NCT01757301 is a clinical study titled "Comprehensive vs. Assisted Management of Mood and Pain Symptoms". Pain is the most common presenting symptom in medical outpatients, and depression and anxiety are the two most common mental disorders. All three conditions are often inadequately treated and result in substantial disability, reduced health-related quality of life, and increased health care costs an...
What is the current status of trial NCT01757301?
This trial is currently completed. It is a NA study. The enrollment target is 296 participants. The study started on 2014-01-02. Estimated completion is 2017-11-30.
What conditions does trial NCT01757301 study?
This clinical trial studies the following conditions: Depression, Pain, Anxiety, Fibromyalgia, Musculoskeletal.
What interventions are being tested in trial NCT01757301?
The interventions under investigation include: Assisted Symptom Management (ASM) (OTHER), Comprehensive Symptom Management (CSM) (OTHER).
Who is sponsoring clinical trial NCT01757301?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01757301 being conducted?
This trial has 1 study location across Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01757301's enrollment target sits among peer trials
296 151st of 679 higher than 529 of 679 other Depression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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