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NCT06866444 · ClinicalTrials.gov registry record
Duloxetine Metabolism and Fibromyalgia
A clinical trial of Fibromyalgia and Duloxetine, sponsored by University of Utah.
- Recruiting
- Registry status
- 100
- Enrollment target
- 1
- Study location
NCT06866444: Recruiting study of Fibromyalgia and Duloxetine, sponsored by University of Utah.
NCT06866444 is a study of Fibromyalgia and Duloxetine that is actively recruiting participants, run by University of Utah. The registered enrollment target is 100 participants, below the 178-participant average among 76 other Fibromyalgia trials with a reported enrollment target (44% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06866444, a study of Fibromyalgia and Duloxetine, is actively recruiting participants, sponsored by University of Utah.
- RECRUITING
- Registry status
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
People with fibromyalgia report generalized body pain ("pain all over"), increased sensitivity to painful stimulation, chronic tiredness or low energy, sleep problems, and other physical and functional problems. The exact cause of the disorder is poorly understood, and treatment can be difficult. The degree to which duloxetine is helpful for people with fibromyalgia varies greatly. For some people, it is very helpful for managing fibromyalgia symptoms. For others, people may not notice any benefit. Yet for some, it is a little helpful and the effect is noticeable only when people forget to take the medicine. The purpose of this study is to collect data to better understand the relationship among gene types that control those enzymes, blood concentrations of duloxetine, and how it helps the symptoms.
Primary Outcome
Metabolizer phenotypes will be separated into 3 groups based on diplotypes. Ultrarapid metabolizer phenotypes will be measured by having an activity score of greater than 2.0. Normal/intermediate metabolizer phenotypes will be measured by having an activity score between 1.0 to 2.0. Slow metabolizer phenotypes will be measured by having an activity score between 0.75 to 0.
Conditions Studied
Interventions
- DRUG Observational
Study Locations (1)
Utah
- Pain Management Center and Pain Research Center at the University of Utah - Salt Lake City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2025-05-01 |
| Est. Completion | 2026-05-01 |
What NCT06866444 shows while recruiting
NCT06866444 is an observational study that tracks outcomes without assigning an intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 178-participant average among 76 other Fibromyalgia trials with a reported enrollment target (44% lower).
The record links to 2 conditions, with Fibromyalgia appearing as the primary indexed condition, and to 1 intervention - of which Observational is the first listed.
NCT06866444 reports a single indexed study location in Utah.
Frequently Asked Questions
What is clinical trial NCT06866444 about?
NCT06866444 is a clinical study titled "Duloxetine Metabolism and Fibromyalgia". People with fibromyalgia report generalized body pain ("pain all over"), increased sensitivity to painful stimulation, chronic tiredness or low energy, sleep problems, and other physical and functional problems. The exact cause of the disorder is poorly understood, and treatment can be difficult. T...
What is the current status of trial NCT06866444?
This trial is currently recruiting. The enrollment target is 100 participants. The study started on 2025-05-01. Estimated completion is 2026-05-01.
What conditions does trial NCT06866444 study?
This clinical trial studies the following conditions: Fibromyalgia, Duloxetine.
What interventions are being tested in trial NCT06866444?
The interventions under investigation include: Observational (DRUG).
Who is sponsoring clinical trial NCT06866444?
This trial is sponsored by University of Utah, which has 818 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06866444 being conducted?
This trial has 1 study location across Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Fibromyalgia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06866444's enrollment target sits among peer trials
100 31st of 76 higher than 44 of 76 other Fibromyalgia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Fibromyalgia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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