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NCT05277025 · ClinicalTrials.gov registry record

Pain Processing in Inflammatory and Non-Inflammatory Chronic Pain Syndromes

A clinical trial of Rheumatoid Arthritis and Fibromyalgia, sponsored by University of Florida.

Recruiting
Registry status
150
Enrollment target
1
Study location

NCT05277025: Recruiting study of Rheumatoid Arthritis and Fibromyalgia, sponsored by University of Florida.

NCT05277025 is a study of Rheumatoid Arthritis and Fibromyalgia that is actively recruiting participants, run by University of Florida. The registered enrollment target is 150 participants, below the 4,690-participant average among 197 other Rheumatoid Arthritis trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05277025, a study of Rheumatoid Arthritis and Fibromyalgia, is actively recruiting participants, sponsored by University of Florida.

RECRUITING
Registry status
150 participants
Enrollment target
1
Study location

Study Summary

Fibromyalgia (FM) is a chronic musculoskeletal pain disorder that afflicts up to 4% of the general population. The evaluation of pain mechanisms in FM has shown predominant central abnormalities and therefore has been designated as nociplastic pain syndrome. Rheumatoid arthritis (RA) is characterized by polyarthritis and pain from inflamed tissues, consistent with nociceptive pain. FM and RA patients may utilize overlapping pain mechanisms resulting in nociceptive and nociplastic pain.

Primary Outcome

Using an algometer pressure pain thresholds will be obtained several times at the upper and lower extremities

Study Locations (1)

Florida

  • University of Florida - Gainesville

Trial Details

FieldValue
Enrollment Target 150 participants
Start Date 2022-03-22
Est. Completion 2026-02-28
University of Florida

1,106 total trials

What NCT05277025 shows while recruiting

NCT05277025 is an observational study that tracks outcomes without assigning an intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, below the 4,690-participant average among 197 other Rheumatoid Arthritis trials with a reported enrollment target (97% lower).

The record links to 2 conditions, with Rheumatoid Arthritis appearing as the primary indexed condition, and to 0 interventions.

NCT05277025 reports a single indexed study location in Florida.

Frequently Asked Questions

What is clinical trial NCT05277025 about?

NCT05277025 is a clinical study titled "Pain Processing in Inflammatory and Non-Inflammatory Chronic Pain Syndromes". Fibromyalgia (FM) is a chronic musculoskeletal pain disorder that afflicts up to 4% of the general population. The evaluation of pain mechanisms in FM has shown predominant central abnormalities and therefore has been designated as nociplastic pain syndrome. Rheumatoid arthritis (RA) is characterize...

What is the current status of trial NCT05277025?

This trial is currently recruiting. The enrollment target is 150 participants. The study started on 2022-03-22. Estimated completion is 2026-02-28.

What conditions does trial NCT05277025 study?

This clinical trial studies the following conditions: Rheumatoid Arthritis, Fibromyalgia.

Who is sponsoring clinical trial NCT05277025?

This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05277025 being conducted?

This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Rheumatoid Arthritis

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05277025's enrollment target sits among peer trials

150 100th of 197 higher than 98 of 197 other Rheumatoid Arthritis trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Rheumatoid Arthritis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05277025, the US trial registry maintained by the National Library of Medicine. NCT05277025 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.