Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Chronic Kidney Disease
Open-data reference.
103 US clinical trials · 32 currently recruiting
Active & Recent Trials
An Observational Study Called FINEROD to Learn More About the Use of the Treatment Finerenone Including How Safe it is and How Well it Works Under Real-world Conditions
Bayer
NCT06278207
The KidneyCARE (Community Access to Research Equity) Study
Tufts Medical Center
NCT05497518
Behavioral AI to Predict and Increase Peritoneal Dialysis Uptake
Scaled Insights
NCT06533254
A Natural History Study of Metabolic Sizing in Health and Disease
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT05398783
Clinical Phenotyping Resource and Biobank Core of the Michigan O'Brien Renal Center
University of Michigan
NCT01016613
Chronic Kidney Disease in Children Prospective Cohort Study (CKiD)
Johns Hopkins Bloomberg School of Public Health
NCT00327860
Proteogenomic Monitoring and Assessment of Liver Transplant Recipients
Northwestern University
NCT01644903
Sickle Cell Kidney Biorepository
University of Texas Southwestern Medical Center
NCT07064174
A Research Study Comparing How Well Different Doses of the Medicine NNC0519-0130 Can Reduce Kidney Damage in People Living With Chronic Kidney Disease
Novo Nordisk A/S
NCT06717698
University of Michigan "Nephrology Research BioBank"
University of Michigan
NCT00381121
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Chronic Kidney Disease
Boehringer Ingelheim
NCT06926660
Transforming Hemodialysis-Related Vascular Access Education
University of Pennsylvania
NCT05997875
Empagliflozin Treatment in Kidney Transplant Recipients
VA Office of Research and Development
NCT06013865
A Study to Learn More About How Well the Study Treatment Finerenone Works, How Safe it is, How it Moves Into, Through, and Out of the Body, and the Effects it Has on the Body When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker in Children With Chronic Kidney Disease and Proteinuria
Bayer
NCT05196035
Intensive Patient Referral and Education Program Prior to Renal Replacement Therapy
University of Chicago
NCT06397456
Patient-driven Management of BP in CKD
VA Office of Research and Development
NCT05546099
Neurovascular Regulation During Exercise in Humans With Chronic Kidney Disease: Sympatholysis in CKD
Emory University
NCT05928936
A Stakeholder-enhanced Intervention to Improve the Decisional Partnership of Chronic Kidney Disease Dyads (IMPART)
University of Alabama at Birmingham
NCT06173323
Pivotal Study of the Velocity™ pAVF System
Venova Medical
NCT07153939
A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4248 in Healthy Participants and Participants With Chronic Kidney Disease and Type 2 Diabetes and to Assess Home Measurements of Creatinine in a Non Interventional Cohort
AstraZeneca
NCT07024823
A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)
Boehringer Ingelheim
NCT07107945
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of OJR520 in Healthy Volunteers and Participants With Chronic Kidney Disease
Novartis Pharmaceuticals
NCT07235059
Sympatholysis in Chronic Kidney Disease
Emory University
NCT02411773
A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria
Bayer
NCT05457283
Safety of Short-course of NSAIDs in Pediatric Patients With CKD
University of Colorado, Denver
NCT06860711
The Impact of Renal Transplant on Coronary Microvascular Function Among Patients With Advanced Chronic Kidney Disease
Brigham and Women's Hospital
NCT07222683
The Epidemiology and Pathophysiology of Kidney Disease in HFpEF With Obesity
University of Mississippi Medical Center
NCT07052539
A Trial of Etelcalcetide in Pediatric Participants With Secondary Hyperparathyroidism and Chronic Kidney Disease on Hemodialysis
Amgen
NCT03633708
Prevalence of Gastric Motor Dysfunction and Upper GI Symptoms in Gastric Antral Vascular Ectasias
Mayo Clinic
NCT06306963
Transcutaneous Auricular Vagus Nerve Stimulation Device in CKD Population
NYU Langone Health
NCT05981183
Staged Kidney Transplantation During Combined Heart/Kidney Transplantation
Cedars-Sinai Medical Center
NCT06877169
L-arginine to Reduce Sympathetic Nerve Activity in CKD Patients
The University of Texas at Arlington
NCT03982160
An Observational Study to Learn More About How Safe Finerenone is and How Well it Works in People With Chronic Kidney Disease and Type 2 Diabetes in Routine Medical Care in the United States
Bayer
NCT06608212
ZEUS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Cardiovascular Disease, Chronic Kidney Disease and Inflammation
Novo Nordisk A/S
NCT05021835
A Study Called FINE-REAL to Learn More About the Use of the Drug Finerenone in a Routine Medical Care Setting
Bayer
NCT05348733
A Study of Daily Oral Orforglipron (LY3502970) Compared With Insulin Glargine in Participants With Type 2 Diabetes and Obesity or Overweight at Increased Cardiovascular Risk
Eli Lilly and Company
NCT05803421
ARTEMIS: Ravulizumab to Protect Patients With CKD From CSA-AKI and MAKE
Alexion Pharmaceuticals
NCT05746559
A Study to Learn About How Well BAY3283142 Works and Its Safety in Participants With Chronic Kidney Disease
Bayer
NCT06522997
Trial to Evaluate and Assess the Effect of Comprehensive Pre-ESKD Education on Home Dialysis Use in Veterans
VA Office of Research and Development
NCT04064086
A Study of Tirzepatide (LY3298176) in Participants With Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 Diabetes
Eli Lilly and Company
NCT05536804
Cancer and Blood Pressure Management, CARISMA Study
ECOG-ACRIN Cancer Research Group
NCT04467021
Dine and DASH Into Wellness Pilot Study
Duke University
NCT07175896
Levels of Inflammation in People With Cardiovascular Disease (POSEIDON)
Novo Nordisk A/S
NCT06122961
EMPA-KIDNEY (The Study of Heart and Kidney Protection With Empagliflozin)
Boehringer Ingelheim
NCT03594110
Folic Acid for Vascular Outcome Reduction In Transplantation (FAVORIT)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00064753
Empowering Patients on Choices for Renal Replacement Therapy (Aim 2)
Arbor Research Collaborative for Health
NCT02440659
A Chronic Care Model Based Quality Improvement (QI) Program to Improve the Care of Patients With Chronic Kidney Disease (CKD)
University of Minnesota
NCT01290614
Dialysis Clinical Outcomes Revisited (DCOR) Trial
Genzyme, a Sanofi Company
NCT00324571
A Study to Learn How Well the Treatment Combination of Finerenone and Empagliflozin Works and How Safe it is Compared to Each Treatment Alone in Adult Participants With Long-term Kidney Disease (Chronic Kidney Disease) and Type 2 Diabetes
Bayer
NCT05254002
Safety & Efficacy of Peginesatide for Maintenance Treatment of Anemia in Participants With Chronic Kidney Disease on Hemodialysis
Affymax
NCT00597753
Telemonitoring to Improve Outcomes of Patients With Chronic Kidney Disease (CKD)
Minneapolis Veterans Affairs Medical Center
NCT01446029
Is There a Digital Divide in Chronic Kidney Disease (CKD)?
Duke University
NCT03067779
Comparing Safety and Immunogenicity of HEPLISAV-B® to Engerix-B® in Chronic Kidney Disease (CKD) Patients
Dynavax Technologies Corporation
NCT00985426
The Effect of Paricalcitol Capsules on Reducing Albuminuria in Patients With Type 2 Diabetic Nephropathy Being Treated With Renin-angiotensin System Inhibitors
Abbott
NCT00421733
Palm Tocotrienols in Chronic Hemodialysis (USA)
Wayne State University
NCT02358967
Diabetes CKD Lifestyle Technology Study
NYU Langone Health
NCT02266823
A Study to Learn How Well the Study Treatment Finerenone Works and How Safe it is in People With Long-term Decrease in the Kidneys' Ability to Work Properly (Chronic Kidney Disease) Together With Type 1 Diabetes
Bayer
NCT05901831
Trial to Determine the Effects of Bardoxolone Methyl on eGFR in Patients With Type 2 Diabetes and Chronic Kidney Disease
Biogen
NCT00811889
20-Week Repeat Oral Dose Study of AKB-6548 in Participants With Chronic Kidney Disease and Anemia
Akebia Therapeutics
NCT01906489
Ferric Citrate for the Transition From CKD Stage 4/5 to CKD Stage 5D
Denver Nephrologists, P.C.
NCT02492620
Conversion Study From Epoetin Alfa to Monthly Peginesatide Injection in Patients With Chronic Kidney Disease on Dialysis
Takeda
NCT01478971
A Study to Evaluate Chitosan Chewing Gum in Patients With Chronic Kidney Disease
Denver Nephrologists, P.C.
NCT01475760
Study of Phosphate Levels in Patients With Chronic Kidney Disease
Vifor Pharma
NCT00824460
Vitamin D and Arterial Function in Patients With Chronic Kidney Disease
University of Colorado, Denver
NCT01384539
Metformin in Kidney Disease
VA Office of Research and Development
NCT02252081
DyeVert™ Plus Contrast Reduction System Multicenter Observational Study
Osprey Medical
NCT03715452
A Research Study to Find Out How Semaglutide Works in the Kidneys Compared to Placebo, in People With Type 2 Diabetes and Chronic Kidney Disease (the REMODEL Trial)
Novo Nordisk A/S
NCT04865770
Sit Less, Interact, Move More (SLIMM) Intervention for Sedentary Behavior in Chronic Kidney Disease (CKD)
Srinvasan Beddhu
NCT02970123
A Video Decision Support Tool to Assist Elderly Patients in ESRD Treatment Decision-making
Massachusetts General Hospital
NCT02698722
Trial to Optimize Mineral Outcomes in Dialysis Patients
University of Colorado, Denver
NCT01100723
Safety & Efficacy of Zirconium Silicate in Chronic Kidney Disease or Moderate Kidney Dysfunction With Mild Hyperkalemia
ZS Pharma
NCT01493024
Endothelial Microparticles: A Novel Marker of Vascular Dysfunction
University of Colorado, Denver
NCT02230202
A Study of Renal Autologous Cell Therapy (REACT) in Type 2 Diabetics With Chronic Kidney Disease
Prokidney
NCT02836574
Phosphate Lowering in CKD Trial
VA Office of Research and Development
NCT02209636
Tocopherols and Alpha Lipoic Acid Treatment Chronic Kidney Disease (TALAT)
Vanderbilt University
NCT00308971
Impact of Ferric Citrate vs Ferrous Sulfate on Iron Parameters and Hemoglobin in Individuals With CKD and Iron Deficiency
University of Alabama at Birmingham
NCT02888171
A Clinical Study to Evaluate the Safety, Tolerability and Activity of a New Phosphate Binder (SBR759) in Patients With Chronic Kidney Disease on Hemodialysis
Novartis Pharmaceuticals
NCT00750295
Extended Release Exenatide Versus Placebo In Diabetic Patients With Type 4 Cardiorenal Syndrome
Baylor Research Institute
NCT02251431
Facilitating Improvements in Kidney Health Using a Smartphone App Counseling Program in Patients With Diabetes
Geisinger Clinic
NCT03015480
Vascular Reactivity in Chronic Kidney Disease (CKD) Patients Receiving Paricalcitol Versus Placebo
Amy Barton Pai
NCT00915876
Hemodialysis Vascular Access Imaging Study
Renal Research Institute
NCT02374762
Effects of Vitamin D Replacement on Hormones Regulating Iron Metabolism in Individuals With Chronic Kidney Disease
University of Alabama at Birmingham
NCT01988116
Rifaximin Therapy in Chronic Kidney Disease
Jason Stubbs, MD
NCT02342639
Cholecalciferol (Vitamin D3) Therapy in Chronic Kidney Disease (CKD) Subjects
Atlanta VA Medical Center
NCT00427037
Bicarbonate Administration and Cognitive Function in Midlife and Older Adults With CKD
University of Colorado, Denver
NCT04600323
FAST GFR: Pilot Study to Evaluate the Safety of the FAST GFR Test in Patients.
FAST BioMedical
NCT01978314
Study to Assess PK, Safety and Tolerability in Patients With DM and CKD
DiaMedica Therapeutics
NCT03795389
Sevelamer and Secondary Hyperparathyroidism in Chronic Kidney Disease
Kenneth R. Phelps, M.D.
NCT01191762
Advanced Glycation End-products, Inflammation and Vascular Health in Chronic Kidney Disease
University of Alabama at Birmingham
NCT01769963
Randomized Controlled Trial of Vitamin D3 in Diabetic Kidney Disease
University of Washington
NCT00552409
Vascular Effects of Mineralocorticoid Receptor Antagonism in Kidney Disease
University of Alabama at Birmingham
NCT02497300
Multicultural Healthy Diet in Chronic Kidney Disease
Montefiore Medical Center
NCT05504850
A Study of RBT-3 in Healthy Volunteers and Volunteers With Stage 3/4 Chronic Kidney Disease
Renibus Therapeutics
NCT04072432
Analysis of Calcium Balance in Chronic Kidney Disease
University of Colorado, Denver
NCT00974532
The Effects of Fiber Fortified Foods to the Diets of Chronic Kidney Disease Patients
University of Florida
NCT01842087
Circadian Rhythm Modulation by Dietary Phosphorus in Chronic Kidney Disease
Geoffrey Block
NCT01341678
Effects of Constipation Treatment in Chronic Kidney Disease: A Pilot Feasibility Trial
University of Tennessee
NCT06123195
Immunologic Abnormalities, Chronic Inflammation and Oxidative Stress in Chronic Kidney Disease
University of California, Irvine
NCT00793806
Effects Of Darbepoetin On Vascular Repair Mechanisms In Kidney Disease The DARBEPC Study
University of Michigan
NCT00396123
A Trial of Doxycycline in Renal Disease
University of California, San Francis
NCT02753426
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 10 |
| Phase 2 | 17 |
| Phase 3 | 19 |
| Phase 4 | 8 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Chronic Kidney Disease Trial Landscape
ClinicalTrials.gov lists 103 US studies indexed under Chronic Kidney Disease, and 32 of those are currently open to recruitment — roughly 31% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Chronic Kidney Disease shows 27 late-stage studies (Phase 3 and Phase 4 combined) alongside 27 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Chronic Kidney Disease is led by Bayer with 8 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 100 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Chronic Kidney Disease?
PlainTrial tracks 103 US clinical trials for Chronic Kidney Disease, of which 32 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Chronic Kidney Disease?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.