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ClinicalTrials.gov 32 recruiting now full pipeline #130 of 28,707 conditions

Chronic Kidney Disease: full-pipeline trial registry

32 of 103 indexed Chronic Kidney Disease trials are currently recruiting.

Corpus placement: #130 of 28,707 conditions by registered trial count.

103 US clinical trials · 32 currently recruiting · #130 of 28,707 conditions by registered trial count

Chronic Kidney Disease: 103 US clinical trials tracked, 32 recruiting.

Chronic Kidney Disease is the subject of 103 registered US clinical trials on ClinicalTrials.gov, 32 of them currently open to new participants. 27 are in Phase 3-4 (later-stage) and 27 in Phase 1-2 (earlier-stage). The most active sponsor is Bayer, running 8 of these trials.

Enrollment posture brief

Registry condition chronic-kidney-disease

OPEN 32 | RECR 31% | LATE 27 | EARLY 27 | RANK #130 | SPON 8

Nearest open-share peer: Eosinophilic Esophagitis (31% recruiting · 45 trials)

Amyotrophic Lateral Sclerosi45.6%Mantle Cell Lymphoma44.7%Chronic Kidney Disease (this)31%Attention Deficit Hyperactiv28.2%Metabolic Syndrome26.9%
Open-enrollment share among volume-matched conditions near Chronic Kidney Disease

Chronic Kidney Disease lists 32 open slots (31% of 103 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Chronic Kidney Disease on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Chronic Kidney Disease is recruiting below its size-band peers.

    32 of 103 indexed trials (31.1%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Chronic Kidney Disease trials is spread across many organizations.

    Bayer accounts for 8 of 103 trials (7.8%). 68 distinct sponsors appear on at least one study for this condition label.

  3. Typical Chronic Kidney Disease enrolment sits around 124 participants.

    Median target enrolment is 124 among the 102 trials that report a genuine target (sentinel values excluded). 43 of those (42.2%) plan for fewer than 100 participants.

  4. Chronic Kidney Disease research is mostly interventional.

    82 interventional and 21 observational studies make up this index (79.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 110Phase 217Phase 319Phase 48

Open and recent trials

103 total, page 1 of 3

RECRUITING 50,000 participants

An Observational Study Called FINEROD to Learn More About the Use of the Treatment Finerenone Including How Safe it is and How Well it Works Under Real-world Conditions

Bayer

NCT06278207

RECRUITING 50,000 participants

The KidneyCARE (Community Access to Research Equity) Study

Tufts Medical Center

NCT05497518

RECRUITING 3,000 participants

Behavioral AI to Predict and Increase Peritoneal Dialysis Uptake

Scaled Insights

NCT06533254

RECRUITING 2,000 participants

A Natural History Study of Metabolic Sizing in Health and Disease

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT05398783

RECRUITING 1,800 participants

Clinical Phenotyping Resource and Biobank Core of the Michigan O'Brien Renal Center

University of Michigan

NCT01016613

RECRUITING 1,300 participants

Chronic Kidney Disease in Children Prospective Cohort Study (CKiD)

Johns Hopkins Bloomberg School of Public Health

NCT00327860

RECRUITING 1,000 participants

Proteogenomic Monitoring and Assessment of Liver Transplant Recipients

Northwestern University

NCT01644903

RECRUITING 800 participants

Sickle Cell Kidney Biorepository

University of Texas Southwestern Medical Center

NCT07064174

RECRUITING Phase 2 465 participants

A Research Study Comparing How Well Different Doses of the Medicine NNC0519-0130 Can Reduce Kidney Damage in People Living With Chronic Kidney Disease

Novo Nordisk A/S

NCT06717698

RECRUITING 420 participants

University of Michigan "Nephrology Research BioBank"

University of Michigan

NCT00381121

RECRUITING Phase 2 416 participants

A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Chronic Kidney Disease

Boehringer Ingelheim

NCT06926660

RECRUITING NA 360 participants

Transforming Hemodialysis-Related Vascular Access Education

University of Pennsylvania

NCT05997875

RECRUITING Phase 4 264 participants

Empagliflozin Treatment in Kidney Transplant Recipients

VA Office of Research and Development

NCT06013865

RECRUITING Phase 3 219 participants

A Study to Learn More About How Well the Study Treatment Finerenone Works, How Safe it is, How it Moves Into, Through, and Out of the Body, and the Effects it Has on the Body When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker in Children With Chronic Kidney Disease and Proteinuria

Bayer

NCT05196035

RECRUITING NA 180 participants

Intensive Patient Referral and Education Program Prior to Renal Replacement Therapy

University of Chicago

NCT06397456

RECRUITING Phase 3 160 participants

Patient-driven Management of BP in CKD

VA Office of Research and Development

NCT05546099

RECRUITING Phase 2 156 participants

Neurovascular Regulation During Exercise in Humans With Chronic Kidney Disease: Sympatholysis in CKD

Emory University

NCT05928936

RECRUITING NA 128 participants

A Stakeholder-enhanced Intervention to Improve the Decisional Partnership of Chronic Kidney Disease Dyads (IMPART)

University of Alabama at Birmingham

NCT06173323

RECRUITING NA 126 participants

Pivotal Study of the Velocity™ pAVF System

Venova Medical

NCT07153939

RECRUITING Phase 1 124 participants

A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4248 in Healthy Participants and Participants With Chronic Kidney Disease and Type 2 Diabetes and to Assess Home Measurements of Creatinine in a Non Interventional Cohort

AstraZeneca

NCT07024823

RECRUITING Phase 3 120 participants

A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)

Boehringer Ingelheim

NCT07107945

RECRUITING Phase 1 112 participants

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of OJR520 in Healthy Volunteers and Participants With Chronic Kidney Disease

Novartis Pharmaceuticals

NCT07235059

RECRUITING Phase 1 110 participants

Sympatholysis in Chronic Kidney Disease

Emory University

NCT02411773

RECRUITING Phase 3 100 participants

A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria

Bayer

NCT05457283

RECRUITING Phase 4 80 participants

Safety of Short-course of NSAIDs in Pediatric Patients With CKD

University of Colorado, Denver

NCT06860711

RECRUITING 80 participants

The Impact of Renal Transplant on Coronary Microvascular Function Among Patients With Advanced Chronic Kidney Disease

Brigham and Women's Hospital

NCT07222683

RECRUITING 60 participants

The Epidemiology and Pathophysiology of Kidney Disease in HFpEF With Obesity

University of Mississippi Medical Center

NCT07052539

RECRUITING Phase 3 56 participants

A Trial of Etelcalcetide in Pediatric Participants With Secondary Hyperparathyroidism and Chronic Kidney Disease on Hemodialysis

Amgen

NCT03633708

RECRUITING 30 participants

Prevalence of Gastric Motor Dysfunction and Upper GI Symptoms in Gastric Antral Vascular Ectasias

Mayo Clinic

NCT06306963

RECRUITING NA 20 participants

Transcutaneous Auricular Vagus Nerve Stimulation Device in CKD Population

NYU Langone Health

NCT05981183

RECRUITING NA 20 participants

Staged Kidney Transplantation During Combined Heart/Kidney Transplantation

Cedars-Sinai Medical Center

NCT06877169

RECRUITING Phase 4 15 participants

L-arginine to Reduce Sympathetic Nerve Activity in CKD Patients

The University of Texas at Arlington

NCT03982160

ACTIVE NOT RECRUITING 150,000 participants

An Observational Study to Learn More About How Safe Finerenone is and How Well it Works in People With Chronic Kidney Disease and Type 2 Diabetes in Routine Medical Care in the United States

Bayer

NCT06608212

ACTIVE NOT RECRUITING Phase 3 6,200 participants

ZEUS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Cardiovascular Disease, Chronic Kidney Disease and Inflammation

Novo Nordisk A/S

NCT05021835

ACTIVE NOT RECRUITING 4,500 participants

A Study Called FINE-REAL to Learn More About the Use of the Drug Finerenone in a Routine Medical Care Setting

Bayer

NCT05348733

ACTIVE NOT RECRUITING Phase 3 2,749 participants

A Study of Daily Oral Orforglipron (LY3502970) Compared With Insulin Glargine in Participants With Type 2 Diabetes and Obesity or Overweight at Increased Cardiovascular Risk

Eli Lilly and Company

NCT05803421

ACTIVE NOT RECRUITING Phase 3 736 participants

ARTEMIS: Ravulizumab to Protect Patients With CKD From CSA-AKI and MAKE

Alexion Pharmaceuticals

NCT05746559

ACTIVE NOT RECRUITING Phase 2 700 participants

A Study to Learn About How Well BAY3283142 Works and Its Safety in Participants With Chronic Kidney Disease

Bayer

NCT06522997

ACTIVE NOT RECRUITING NA 656 participants

Trial to Evaluate and Assess the Effect of Comprehensive Pre-ESKD Education on Home Dialysis Use in Veterans

VA Office of Research and Development

NCT04064086

ACTIVE NOT RECRUITING Phase 2 140 participants

A Study of Tirzepatide (LY3298176) in Participants With Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 Diabetes

Eli Lilly and Company

NCT05536804

ACTIVE NOT RECRUITING NA 61 participants

Cancer and Blood Pressure Management, CARISMA Study

ECOG-ACRIN Cancer Research Group

NCT04467021

ACTIVE NOT RECRUITING NA 48 participants

Dine and DASH Into Wellness Pilot Study

Duke University

NCT07175896

COMPLETED 18,198 participants

Levels of Inflammation in People With Cardiovascular Disease (POSEIDON)

Novo Nordisk A/S

NCT06122961

COMPLETED Phase 3 6,609 participants

EMPA-KIDNEY (The Study of Heart and Kidney Protection With Empagliflozin)

Boehringer Ingelheim

NCT03594110

COMPLETED Phase 2 4,110 participants

Folic Acid for Vascular Outcome Reduction In Transplantation (FAVORIT)

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT00064753

COMPLETED 2,946 participants

Empowering Patients on Choices for Renal Replacement Therapy (Aim 2)

Arbor Research Collaborative for Health

NCT02440659

COMPLETED Phase 4 2,199 participants

A Chronic Care Model Based Quality Improvement (QI) Program to Improve the Care of Patients With Chronic Kidney Disease (CKD)

University of Minnesota

NCT01290614

COMPLETED Phase 4 2,000 participants

Dialysis Clinical Outcomes Revisited (DCOR) Trial

Genzyme, a Sanofi Company

NCT00324571

COMPLETED Phase 2 1,664 participants

A Study to Learn How Well the Treatment Combination of Finerenone and Empagliflozin Works and How Safe it is Compared to Each Treatment Alone in Adult Participants With Long-term Kidney Disease (Chronic Kidney Disease) and Type 2 Diabetes

Bayer

NCT05254002

COMPLETED Phase 3 803 participants

Safety & Efficacy of Peginesatide for Maintenance Treatment of Anemia in Participants With Chronic Kidney Disease on Hemodialysis

Affymax

NCT00597753

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Phase Distribution

PhaseTrial count
Phase 1 10
Phase 2 17
Phase 3 19
Phase 4 8

Named interventions

Most-linked intervention names on Chronic Kidney Disease records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
20 trials
Empagliflozin Drug
5 trials
Placebo Other
5 trials
placebo Drug
3 trials
Cholecalciferol Drug
2 trials
Finerenone (Kerendia, BAY94-8862) Drug
2 trials
Semaglutide Drug
2 trials
Exercise Training Behavioral
2 trials

US sites by state

Facility locations filed on Chronic Kidney Disease trials. A trial with sites in several states counts in each.

California 31 trials
Florida 26 trials
Colorado 20 trials
Illinois 19 trials
Texas 18 trials
Georgia 18 trials
Arizona 18 trials
Alabama 17 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Chronic Kidney Disease page

103 registered trials, 32 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 32 Chronic Kidney Disease trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Bayer sponsors the most Chronic Kidney Disease trials on record, review their full trial history before evaluating a specific study. See Bayer's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Chronic Kidney Disease condition card totals 103 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.