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ClinicalTrials.gov 32 recruiting now official registry

Chronic Kidney Disease clinical trials

32 of 103 indexed Chronic Kidney Disease trials are currently recruiting.

103 US clinical trials · 32 currently recruiting

Chronic Kidney Disease is the subject of 103 registered US clinical trials on ClinicalTrials.gov, 32 of them currently open to new participants. 27 are in Phase 3-4 (later-stage) and 27 in Phase 1-2 (earlier-stage). The most active sponsor is Bayer, running 8 of these trials.

The research picture

Chronic Kidney Disease has 103 registered US clinical trials, 32 of them open to new participants right now, about 31% of the total.

32
recruiting participants now
31%
of trials open to enrollment
27
in Phase 3–4 (later-stage)
8
top sponsor: Bayer
Phase 110Phase 217Phase 319Phase 48

Active & Recent Trials

103 total, page 1 of 3

RECRUITING 50,000 participants

An Observational Study Called FINEROD to Learn More About the Use of the Treatment Finerenone Including How Safe it is and How Well it Works Under Real-world Conditions

Bayer

NCT06278207

RECRUITING 50,000 participants

The KidneyCARE (Community Access to Research Equity) Study

Tufts Medical Center

NCT05497518

RECRUITING 3,000 participants

Behavioral AI to Predict and Increase Peritoneal Dialysis Uptake

Scaled Insights

NCT06533254

RECRUITING 2,000 participants

A Natural History Study of Metabolic Sizing in Health and Disease

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT05398783

RECRUITING 1,800 participants

Clinical Phenotyping Resource and Biobank Core of the Michigan O'Brien Renal Center

University of Michigan

NCT01016613

RECRUITING 1,300 participants

Chronic Kidney Disease in Children Prospective Cohort Study (CKiD)

Johns Hopkins Bloomberg School of Public Health

NCT00327860

RECRUITING 1,000 participants

Proteogenomic Monitoring and Assessment of Liver Transplant Recipients

Northwestern University

NCT01644903

RECRUITING 800 participants

Sickle Cell Kidney Biorepository

University of Texas Southwestern Medical Center

NCT07064174

RECRUITING Phase 2 465 participants

A Research Study Comparing How Well Different Doses of the Medicine NNC0519-0130 Can Reduce Kidney Damage in People Living With Chronic Kidney Disease

Novo Nordisk A/S

NCT06717698

RECRUITING 420 participants

University of Michigan "Nephrology Research BioBank"

University of Michigan

NCT00381121

RECRUITING Phase 2 416 participants

A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Chronic Kidney Disease

Boehringer Ingelheim

NCT06926660

RECRUITING NA 360 participants

Transforming Hemodialysis-Related Vascular Access Education

University of Pennsylvania

NCT05997875

RECRUITING Phase 4 264 participants

Empagliflozin Treatment in Kidney Transplant Recipients

VA Office of Research and Development

NCT06013865

RECRUITING Phase 3 219 participants

A Study to Learn More About How Well the Study Treatment Finerenone Works, How Safe it is, How it Moves Into, Through, and Out of the Body, and the Effects it Has on the Body When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker in Children With Chronic Kidney Disease and Proteinuria

Bayer

NCT05196035

RECRUITING NA 180 participants

Intensive Patient Referral and Education Program Prior to Renal Replacement Therapy

University of Chicago

NCT06397456

RECRUITING Phase 3 160 participants

Patient-driven Management of BP in CKD

VA Office of Research and Development

NCT05546099

RECRUITING Phase 2 156 participants

Neurovascular Regulation During Exercise in Humans With Chronic Kidney Disease: Sympatholysis in CKD

Emory University

NCT05928936

RECRUITING NA 128 participants

A Stakeholder-enhanced Intervention to Improve the Decisional Partnership of Chronic Kidney Disease Dyads (IMPART)

University of Alabama at Birmingham

NCT06173323

RECRUITING NA 126 participants

Pivotal Study of the Velocity™ pAVF System

Venova Medical

NCT07153939

RECRUITING Phase 1 124 participants

A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4248 in Healthy Participants and Participants With Chronic Kidney Disease and Type 2 Diabetes and to Assess Home Measurements of Creatinine in a Non Interventional Cohort

AstraZeneca

NCT07024823

RECRUITING Phase 3 120 participants

A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)

Boehringer Ingelheim

NCT07107945

RECRUITING Phase 1 112 participants

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of OJR520 in Healthy Volunteers and Participants With Chronic Kidney Disease

Novartis Pharmaceuticals

NCT07235059

RECRUITING Phase 1 110 participants

Sympatholysis in Chronic Kidney Disease

Emory University

NCT02411773

RECRUITING Phase 3 100 participants

A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria

Bayer

NCT05457283

RECRUITING Phase 4 80 participants

Safety of Short-course of NSAIDs in Pediatric Patients With CKD

University of Colorado, Denver

NCT06860711

RECRUITING 80 participants

The Impact of Renal Transplant on Coronary Microvascular Function Among Patients With Advanced Chronic Kidney Disease

Brigham and Women's Hospital

NCT07222683

RECRUITING 60 participants

The Epidemiology and Pathophysiology of Kidney Disease in HFpEF With Obesity

University of Mississippi Medical Center

NCT07052539

RECRUITING Phase 3 56 participants

A Trial of Etelcalcetide in Pediatric Participants With Secondary Hyperparathyroidism and Chronic Kidney Disease on Hemodialysis

Amgen

NCT03633708

RECRUITING 30 participants

Prevalence of Gastric Motor Dysfunction and Upper GI Symptoms in Gastric Antral Vascular Ectasias

Mayo Clinic

NCT06306963

RECRUITING NA 20 participants

Transcutaneous Auricular Vagus Nerve Stimulation Device in CKD Population

NYU Langone Health

NCT05981183

RECRUITING NA 20 participants

Staged Kidney Transplantation During Combined Heart/Kidney Transplantation

Cedars-Sinai Medical Center

NCT06877169

RECRUITING Phase 4 15 participants

L-arginine to Reduce Sympathetic Nerve Activity in CKD Patients

The University of Texas at Arlington

NCT03982160

ACTIVE NOT RECRUITING 150,000 participants

An Observational Study to Learn More About How Safe Finerenone is and How Well it Works in People With Chronic Kidney Disease and Type 2 Diabetes in Routine Medical Care in the United States

Bayer

NCT06608212

ACTIVE NOT RECRUITING Phase 3 6,200 participants

ZEUS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Cardiovascular Disease, Chronic Kidney Disease and Inflammation

Novo Nordisk A/S

NCT05021835

ACTIVE NOT RECRUITING 4,500 participants

A Study Called FINE-REAL to Learn More About the Use of the Drug Finerenone in a Routine Medical Care Setting

Bayer

NCT05348733

ACTIVE NOT RECRUITING Phase 3 2,749 participants

A Study of Daily Oral Orforglipron (LY3502970) Compared With Insulin Glargine in Participants With Type 2 Diabetes and Obesity or Overweight at Increased Cardiovascular Risk

Eli Lilly and Company

NCT05803421

ACTIVE NOT RECRUITING Phase 3 736 participants

ARTEMIS: Ravulizumab to Protect Patients With CKD From CSA-AKI and MAKE

Alexion Pharmaceuticals

NCT05746559

ACTIVE NOT RECRUITING Phase 2 700 participants

A Study to Learn About How Well BAY3283142 Works and Its Safety in Participants With Chronic Kidney Disease

Bayer

NCT06522997

ACTIVE NOT RECRUITING NA 656 participants

Trial to Evaluate and Assess the Effect of Comprehensive Pre-ESKD Education on Home Dialysis Use in Veterans

VA Office of Research and Development

NCT04064086

ACTIVE NOT RECRUITING Phase 2 140 participants

A Study of Tirzepatide (LY3298176) in Participants With Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 Diabetes

Eli Lilly and Company

NCT05536804

ACTIVE NOT RECRUITING NA 61 participants

Cancer and Blood Pressure Management, CARISMA Study

ECOG-ACRIN Cancer Research Group

NCT04467021

ACTIVE NOT RECRUITING NA 48 participants

Dine and DASH Into Wellness Pilot Study

Duke University

NCT07175896

COMPLETED 18,198 participants

Levels of Inflammation in People With Cardiovascular Disease (POSEIDON)

Novo Nordisk A/S

NCT06122961

COMPLETED Phase 3 6,609 participants

EMPA-KIDNEY (The Study of Heart and Kidney Protection With Empagliflozin)

Boehringer Ingelheim

NCT03594110

COMPLETED Phase 2 4,110 participants

Folic Acid for Vascular Outcome Reduction In Transplantation (FAVORIT)

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT00064753

COMPLETED 2,946 participants

Empowering Patients on Choices for Renal Replacement Therapy (Aim 2)

Arbor Research Collaborative for Health

NCT02440659

COMPLETED Phase 4 2,199 participants

A Chronic Care Model Based Quality Improvement (QI) Program to Improve the Care of Patients With Chronic Kidney Disease (CKD)

University of Minnesota

NCT01290614

COMPLETED Phase 4 2,000 participants

Dialysis Clinical Outcomes Revisited (DCOR) Trial

Genzyme, a Sanofi Company

NCT00324571

COMPLETED Phase 2 1,664 participants

A Study to Learn How Well the Treatment Combination of Finerenone and Empagliflozin Works and How Safe it is Compared to Each Treatment Alone in Adult Participants With Long-term Kidney Disease (Chronic Kidney Disease) and Type 2 Diabetes

Bayer

NCT05254002

COMPLETED Phase 3 803 participants

Safety & Efficacy of Peginesatide for Maintenance Treatment of Anemia in Participants With Chronic Kidney Disease on Hemodialysis

Affymax

NCT00597753

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Phase Distribution

PhaseTrial count
Phase 1 10
Phase 2 17
Phase 3 19
Phase 4 8

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Chronic Kidney Disease Trial Landscape

103 indexed Chronic Kidney Disease studies · 32 recruiting (31%).

Phase mix: 27 late (III/IV) vs 27 early (I/II).

Top sponsor: Bayer (8 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Chronic Kidney Disease?

PlainTrial tracks 103 US clinical trials for Chronic Kidney Disease, of which 32 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Chronic Kidney Disease?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.