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NCT02546219 · ClinicalTrials.gov registry record
a4b7 Integrin in Eosinophilic Esophagitis
A clinical trial of Eosinophilic Esophagitis, sponsored by Massachusetts General Hospital.
- Completed
- Registry status
- 16
- Enrollment target
- 1
- Study location
NCT02546219 is a study of Eosinophilic Esophagitis that has completed, run by Massachusetts General Hospital. The registered enrollment target is 16 participants, below the 864-participant average among 44 other Eosinophilic Esophagitis trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.
The verdict
NCT02546219, a study of Eosinophilic Esophagitis, has completed, sponsored by Massachusetts General Hospital.
- COMPLETED
- Registry status
- 16 participants
- Enrollment target
- 1
- Study location
Study Summary
The overall objective of this preclinical study is to further the investigators mechanistic understanding of the role that the α4β7 and mucosal addressin cell adhesion molecule (MAdCAM-1) pathway plays in mediating eosinophil recruitment in EoE. To accomplish this, the investigators aim to (1) determine the baseline and dynamic patterns of α4β7 integrin expression on circulating and tissue eosinophils in EoE and in the setting of non-EoE esophageal eosinophilia (e.g., reflux esophagitis) and (2) determine the complete profile of eosinophil integrin molecules that may play a role in active EoE.
Conditions Studied
Interventions
- OTHER Eosinophil isolation and characterization.
Study Locations (1)
Massachusetts
- Massachusetts General Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2016-03 |
| Est. Completion | 2018-12-31 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02546219
The ClinicalTrials.gov registry entry for NCT02546219 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 16 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 864-participant average among 44 other Eosinophilic Esophagitis trials with a reported enrollment target (98% lower). The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Eosinophilic Esophagitis appearing as the primary indexed condition, and to 1 intervention - of which Eosinophil isolation and characterization. is the first listed.
NCT02546219 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.
Frequently Asked Questions
What is clinical trial NCT02546219 about?
NCT02546219 is a clinical study titled "a4b7 Integrin in Eosinophilic Esophagitis". The overall objective of this preclinical study is to further the investigators mechanistic understanding of the role that the α4β7 and mucosal addressin cell adhesion molecule (MAdCAM-1) pathway plays in mediating eosinophil recruitment in EoE. To accomplish this, the investigators aim to (1) deter...
What is the current status of trial NCT02546219?
This trial is currently completed. The enrollment target is 16 participants. The study started on 2016-03. Estimated completion is 2018-12-31.
What conditions does trial NCT02546219 study?
This clinical trial studies the following conditions: Eosinophilic Esophagitis.
What interventions are being tested in trial NCT02546219?
The interventions under investigation include: Eosinophil isolation and characterization. (OTHER).
Who is sponsoring clinical trial NCT02546219?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02546219 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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