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NCT01022970 · ClinicalTrials.gov registry record · Phase 2

Efficacy and Safety of QAX576 in Patients With Eosinophilic Esophagitis

A Phase 2 study of Eosinophilic Esophagitis, sponsored by Novartis Pharmaceuticals.

Completed
Registry status
Phase 2
Development phase
25
Enrollment target
5
Study locations

NCT01022970 is a Phase 2 study of Eosinophilic Esophagitis that has completed, run by Novartis Pharmaceuticals. The registered enrollment target is 25 participants, below the 864-participant average among 44 other Eosinophilic Esophagitis trials with a reported enrollment target (97% lower). The trial reports 5 study locations across 5 states.

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The verdict

NCT01022970, a Phase 2 study of Eosinophilic Esophagitis, has completed, sponsored by Novartis Pharmaceuticals.

COMPLETED
Registry status
Phase 2
Development phase
25 participants
Enrollment target
5
Study locations

Study Summary

This study is designed to investigate the effects of a 12 week course of intravenous QAX576 6mg/kg every 4 weeks in reducing the number of eosinophils in the esophagus of EoE patients by 75% or greater when compared with baseline.

Conditions Studied

Interventions

  • DRUG QAX576 placebo
  • DRUG QAX576

Study Locations (5)

California

  • Stanford Medical Center and Lucile Packard Children's Hospital - Stanford

Illinois

  • Northwestern University Feinberg School of Medicine - Chicago

Minnesota

  • Mayo Clinic - Minneota

Ohio

  • Cincinnati Children's Hospital Medical Center - Cincinnati

Virginia

  • Oral Alpan, 6210 Old Keene Mill Court, - Springfield

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2009-11
Phase Phase 2

Sponsor

Novartis Pharmaceuticals

1,375 total trials

What the Registry Record Tells You About NCT01022970

The ClinicalTrials.gov registry entry for NCT01022970 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 25 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 864-participant average among 44 other Eosinophilic Esophagitis trials with a reported enrollment target (97% lower). The listed sponsor is Novartis Pharmaceuticals, which has 1,375 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Eosinophilic Esophagitis appearing as the primary indexed condition, and to 2 interventions - of which QAX576 placebo is the first listed.

NCT01022970 reports 5 study locations spanning 5 distinct geographic areas - top geographies include California, Illinois, Minnesota.

Frequently Asked Questions

What is clinical trial NCT01022970 about?

NCT01022970 is a clinical study titled "Efficacy and Safety of QAX576 in Patients With Eosinophilic Esophagitis". This study is designed to investigate the effects of a 12 week course of intravenous QAX576 6mg/kg every 4 weeks in reducing the number of eosinophils in the esophagus of EoE patients by 75% or greater when compared with baseline.

What is the current status of trial NCT01022970?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 25 participants. The study started on 2009-11.

What conditions does trial NCT01022970 study?

This clinical trial studies the following conditions: Eosinophilic Esophagitis.

What interventions are being tested in trial NCT01022970?

The interventions under investigation include: QAX576 placebo (DRUG), QAX576 (DRUG).

Who is sponsoring clinical trial NCT01022970?

This trial is sponsored by Novartis Pharmaceuticals, which has 1,375 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01022970 being conducted?

This trial has 5 study locations across California, Illinois, Minnesota, Ohio, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.