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NCT01988285 · ClinicalTrials.gov registry record
Risk Factors and Biomarkers for Diagnosis and Treatment of EoE
A clinical trial of Eosinophilic Esophagitis, sponsored by University of North Carolina, Chapel Hill.
- Active
- Registry status
- 800
- Enrollment target
- 1
- Study location
NCT01988285 is a study of Eosinophilic Esophagitis that is active but no longer recruiting, run by University of North Carolina, Chapel Hill. The registered enrollment target is 800 participants, roughly in line with the 846-participant average among 44 other Eosinophilic Esophagitis trials with a reported enrollment target. The trial reports 1 study location across 1 state.
The verdict
NCT01988285, a study of Eosinophilic Esophagitis, is active but no longer recruiting, sponsored by University of North Carolina, Chapel Hill.
- ACTIVE NOT RECRUITING
- Registry status
- 800 participants
- Enrollment target
- 1
- Study location
Study Summary
Purpose: To validate our previously developed model of risk factors for diagnosis of eosinophilic esophagitis (EoE), and to assess the utility of serum levels of biomarkers in diagnosis and monitoring of treatment of EoE. Participants: Up to a total of 800 participants (approximately 400 with EoE and 400 without EoE) who are referred for upper endoscopy. Procedures: This is a prospective cohort study. Patients will be compared with newly diagnosed EoE to non-EoE controls, obtain baseline measures, reassess EoE patients after treatment, and also reassess untreated controls. Data collection will include questionnaire results, blood collection, and tissue collection (esophageal biopsies performed during upper endoscopy per pre-specified protocol). Blood will be analyzed for the presence of the candidate biomarkers. Patients will be compared with newly diagnosed EoE to non-EoE controls, obtain baseline measures, reassess EoE patients after treatment, and also reassess untreated controls. Data collection will include questionnaire results, blood collection, possible saliva collection, possible urine collection, and tissue collection (esophageal biopsies performed during upper endoscopy per pre-specified protocol). Blood will be analyzed for the presence of the candidate biomarkers, including eotaxin-3 and IL-13.
Conditions Studied
Interventions
- OTHER Questionnaires
- OTHER Specimen Collection
Study Locations (1)
North Carolina
- University of North Carolina, Chapel Hill - Chapel Hill
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 800 participants |
| Start Date | 2011-07 |
| Est. Completion | 2026-08 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01988285
The ClinicalTrials.gov registry entry for NCT01988285 describes a study currently listed as active not recruiting, categorized as an unspecified phase. The registered enrollment target is 800 participants, a figure that helps gauge the scale of data the investigators plan to collect, roughly in line with the 846-participant average among 44 other Eosinophilic Esophagitis trials with a reported enrollment target. The listed sponsor is University of North Carolina, Chapel Hill, which has 1,109 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Eosinophilic Esophagitis appearing as the primary indexed condition, and to 2 interventions - of which Questionnaires is the first listed.
NCT01988285 reports 1 study location spanning 1 distinct geographic area - top geographies include North Carolina.
Frequently Asked Questions
What is clinical trial NCT01988285 about?
NCT01988285 is a clinical study titled "Risk Factors and Biomarkers for Diagnosis and Treatment of EoE". Purpose: To validate our previously developed model of risk factors for diagnosis of eosinophilic esophagitis (EoE), and to assess the utility of serum levels of biomarkers in diagnosis and monitoring of treatment of EoE. Participants: Up to a total of 800 participants (approximately 400 with EoE an...
What is the current status of trial NCT01988285?
This trial is currently active not recruiting. The enrollment target is 800 participants. The study started on 2011-07. Estimated completion is 2026-08.
What conditions does trial NCT01988285 study?
This clinical trial studies the following conditions: Eosinophilic Esophagitis.
What interventions are being tested in trial NCT01988285?
The interventions under investigation include: Questionnaires (OTHER), Specimen Collection (OTHER).
Who is sponsoring clinical trial NCT01988285?
This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01988285 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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