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Arthritis: early-phase trial registry
15 of 49 indexed Arthritis trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #281 of 28,707 conditions by registered trial count.
49 US clinical trials · 15 currently recruiting · #281 of 28,707 conditions by registered trial count
Arthritis: 49 US clinical trials tracked, 15 recruiting.
Arthritis is the subject of 49 registered US clinical trials on ClinicalTrials.gov, 15 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 11 in Phase 1-2 (earlier-stage). The most active sponsor is National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), running 4 of these trials.
Enrollment posture brief
Registry condition arthritis
OPEN 15 | RECR 31% | LATE 2 | EARLY 11 | RANK #281 | SPON 4
Volume-matched condition peers
Nearest open-share peer: Loneliness (31% recruiting · 36 trials)
Arthritis lists 15 open slots (31% of 49 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Arthritis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Arthritis is recruiting below its size-band peers.
15 of 49 indexed trials (30.6%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Arthritis trials is spread across many organizations.
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) accounts for 4 of 49 trials (8.2%). 37 distinct sponsors appear on at least one study for this condition label.
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Typical Arthritis enrolment sits around 154 participants.
Median target enrolment is 154 among the 49 trials that report a genuine target (sentinel values excluded). 21 of those (42.9%) plan for fewer than 100 participants.
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Arthritis research is mostly interventional.
36 interventional and 13 observational studies make up this index (73.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
49 total, page 1 of 1
Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives
Sanguine Biosciences
NCT05635266
Studies of the Natural History of Rheumatic Diseases
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NCT00024479
Natural History and Development of Spondyloarthritis
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NCT01422694
Natural History, Genetics, and Pathophysiology of Systemic Juvenile Idiopathic Arthritis, Adult-Onset Still's Disease, and Related Conditions
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NCT03510442
Study of Dapansutrile Tablets in Subjects With an Acute Gout Flare
Olatec Therapeutics
NCT05658575
Sustained Acoustic Medicine for Symptomatic Treatment of Knee Pain Related to Osteoarthritis
ZetrOZ
NCT06257537
Dose Response of Exercise for Arthritis Management
University of South Carolina
NCT06880653
Evaluation of the Walk With Ease Program for Fall Prevention
Iowa State University
NCT05693025
Ultralow Dose PET Imaging for 18F-NaF Uptake
Akiva Mintz
NCT07284563
Impact of Biophoton Therapy on Chronic Severe Arthritis Pain
First Institute of All Medicines
NCT06915012
Aptis PRUJ Prosthesis for the Treatment of Patients With Proximal Radial Ulna Joint Disorders.
Aptis Medical
NCT05796908
Expanding Exercise Programming for Veterans Through Telehealth
VA Office of Research and Development
NCT05666167
The Benefits of Natural Medicine, Vitamin IV Therapy and Supplements: Maintaining Good Health Through Nature
Faith A. Richardson
NCT05067998
A Qualitative Assessment of the Severity and Impact of Rheumatic Immune-Related Adverse Events Following Immune Checkpoint Inhibitor Immunotherapy
M.D. Anderson Cancer Center
NCT06647134
Geniculate Artery Embolization for Osteoarthritis
University of Minnesota
NCT04456569
Improving Virtual Care of Arthritis: Integrating a Smartphone App Into the EHR for Improved Timeliness of Visits
Brigham and Women's Hospital
NCT06004700
SakuraBead Used as Resorbable Embolic for Genicular Artery Embolization
CrannMed
NCT06550024
Impact of Different Exercise Programs on Knee OA
Shirley Ryan AbilityLab
NCT05844124
Comparing Functional Outcomes in Individuals Using Micro-processor Controlled Orthosis Versus Stance Control Orthosis
Shirley Ryan AbilityLab
NCT02089880
Deep Dive Randomized Control Trial
Health Dialog
NCT00793260
Ultrarunners Longitudinal TRAcking Study (ULTRA)
Stanford University
NCT02014038
Clinical Study Evaluating an Acetabular Cup System After Total Hip Replacement
DePuy Orthopaedics
NCT00306930
The Pathogenesis of Inflammatory Synovitis: A Study of Early Arthritis
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NCT00001375
Evaluation of Walk With Ease in Arthritis
Centers for Disease Control and Prevention
NCT00526435
Golimumab in Rheumatoid Arthritis Participants With an Inadequate Response to Etanercept (ENBREL) or Adalimumab (HUMIRA)
Janssen Biotech
NCT01004432
Comparing ASHC and CDSMP Outcomes In Arthritis
Centers for Disease Control and Prevention
NCT00207441
The Health Access and Recovery Peer Program
Emory University
NCT01725815
Trial Outcomes for Massage: Caregiver-Assisted vs. Therapist-Treated
VA Office of Research and Development
NCT03100539
Staying Positive With Arthritis Study
VA Office of Research and Development
NCT02223858
A Safety and Efficacy Study of the Birmingham Hip Resurfacing System
Smith & Nephew
NCT00611585
Study Comparing Marathon Polyethylene and Enduron Polyethylene Acetabular Liners Used in Total Hip Arthroplasty
Anderson Orthopaedic Research Institute
NCT01121146
Marathon and Enduron Polyethylene at Long-Term Follow-up
Anderson Orthopaedic Research Institute
NCT02508428
Sustained Acoustic Medicine (SAM) for Symptomatic Treatment of Knee Pain Related to Osteoarthritis
ZetrOZ
NCT05882812
Fitness and Exercise for People With Arthritis
Centers for Disease Control and Prevention
NCT00252070
Ultrasound Guided Arthrocentesis
Wake Forest University Health Sciences
NCT00537589
Regenerex Tibial Tray Multi-Center Data Collection
Zimmer Biomet
NCT00859963
Mechanisms of Action of Acetaminophen
University of Pennsylvania
NCT00646906
Safety and Efficacy of Gardasil in Females With Juvenile Idiopathic Arthritis (JIA)/Seronegative Arthritis
University Hospitals Cleveland Medical Center
NCT00573651
Sustained Acoustic Medicine (SAM) Combined With a Diclofenac Ultrasound Coupling Patch for Knee Osteoarthritis
ZetrOZ
NCT04391842
Modifying Exercise for the COPD Patient
Angela N Fellner PhD CCRP
NCT02143206
Study Evaluating the Bioavailability of Naproxen 375 mg in Two Formulations
POZEN
NCT00692055
Followup of Glenoid Fix Utilizing Auto Bone Graft in Shoulder Replacement
University of Nebraska
NCT00670852
Biomarker-Linked Outcomes of Cellcept in Lupus Arthritis
Oklahoma Medical Research Foundation
NCT00594932
Allograft Meniscal Arthroplasty for the Treatment of Basal Joint Arthritis of the Thumb
Corewell Health East
NCT01542515
Horses and Education as Arthritis Therapy
University of Missouri, Kansas City
NCT03141853
A Randomized, Double-Blind, Dose-Response Study of the Safety and Uric Acid Effects of Oral Ulodesine Added to Allopurinol in Subjects With Gout and Concomitant Moderate Renal Insufficiency
BioCryst Pharmaceuticals
NCT01407874
Yoga as Self-Care for Arthritis in Minority Communities
National Institutes of Health Clinical Center (CC)
NCT01617421
Long Term Outcomes Follow-up of Glenoid Anchor Peg Component Fixation
University of Nebraska
NCT02983357
Pharmacokinetics and Metabolism Study of Radiolabeled BMS-986142 in Healthy Male Subjects
Bristol-Myers Squibb
NCT02880670
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 5 |
| Phase 2 | 6 |
| Phase 3 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Arthritis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Arthritis trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Arthritis page
49 registered trials, 15 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 15 Arthritis trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) sponsors the most Arthritis trials on record, review their full trial history before evaluating a specific study. See National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)'s trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Arthritis condition card totals 49 registered trials; most-linked intervention Sustained Acoustic Device with 0% Diclofenac Patch; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.