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2026 data Public-data reference. official source

Arthritis

Open-data reference.

49 US clinical trials · 15 currently recruiting

Active & Recent Trials

RECRUITING 20,000 participants

Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives

Sanguine Biosciences

NCT05635266

RECRUITING 7,500 participants

Studies of the Natural History of Rheumatic Diseases

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

NCT00024479

RECRUITING 2,000 participants

Natural History and Development of Spondyloarthritis

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

NCT01422694

RECRUITING 2,000 participants

Natural History, Genetics, and Pathophysiology of Systemic Juvenile Idiopathic Arthritis, Adult-Onset Still's Disease, and Related Conditions

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

NCT03510442

RECRUITING Phase 2 300 participants

Study of Dapansutrile Tablets in Subjects With an Acute Gout Flare

Olatec Therapeutics

NCT05658575

RECRUITING Phase 2 300 participants

Sustained Acoustic Medicine for Symptomatic Treatment of Knee Pain Related to Osteoarthritis

ZetrOZ

NCT06257537

RECRUITING NA 285 participants

Dose Response of Exercise for Arthritis Management

University of South Carolina

NCT06880653

RECRUITING Phase 1 240 participants

Evaluation of the Walk With Ease Program for Fall Prevention

Iowa State University

NCT05693025

RECRUITING Phase 2 200 participants

Ultralow Dose PET Imaging for 18F-NaF Uptake

Akiva Mintz

NCT07284563

RECRUITING NA 102 participants

Impact of Biophoton Therapy on Chronic Severe Arthritis Pain

First Institute of All Medicines

NCT06915012

RECRUITING NA 84 participants

Aptis PRUJ Prosthesis for the Treatment of Patients With Proximal Radial Ulna Joint Disorders.

Aptis Medical

NCT05796908

RECRUITING NA 50 participants

Expanding Exercise Programming for Veterans Through Telehealth

VA Office of Research and Development

NCT05666167

RECRUITING 25 participants

The Benefits of Natural Medicine, Vitamin IV Therapy and Supplements: Maintaining Good Health Through Nature

Faith A. Richardson

NCT05067998

RECRUITING 20 participants

A Qualitative Assessment of the Severity and Impact of Rheumatic Immune-Related Adverse Events Following Immune Checkpoint Inhibitor Immunotherapy

M.D. Anderson Cancer Center

NCT06647134

RECRUITING NA 20 participants

Geniculate Artery Embolization for Osteoarthritis

University of Minnesota

NCT04456569

ACTIVE NOT RECRUITING NA 278 participants

Improving Virtual Care of Arthritis: Integrating a Smartphone App Into the EHR for Improved Timeliness of Visits

Brigham and Women's Hospital

NCT06004700

ACTIVE NOT RECRUITING NA 89 participants

SakuraBead Used as Resorbable Embolic for Genicular Artery Embolization

CrannMed

NCT06550024

ACTIVE NOT RECRUITING NA 60 participants

Impact of Different Exercise Programs on Knee OA

Shirley Ryan AbilityLab

NCT05844124

ACTIVE NOT RECRUITING NA 24 participants

Comparing Functional Outcomes in Individuals Using Micro-processor Controlled Orthosis Versus Stance Control Orthosis

Shirley Ryan AbilityLab

NCT02089880

COMPLETED NA 174,120 participants

Deep Dive Randomized Control Trial

Health Dialog

NCT00793260

COMPLETED 2,452 participants

Ultrarunners Longitudinal TRAcking Study (ULTRA)

Stanford University

NCT02014038

COMPLETED NA 1,593 participants

Clinical Study Evaluating an Acetabular Cup System After Total Hip Replacement

DePuy Orthopaedics

NCT00306930

COMPLETED 500 participants

The Pathogenesis of Inflammatory Synovitis: A Study of Early Arthritis

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

NCT00001375

COMPLETED Phase 3 468 participants

Evaluation of Walk With Ease in Arthritis

Centers for Disease Control and Prevention

NCT00526435

COMPLETED Phase 3 433 participants

Golimumab in Rheumatoid Arthritis Participants With an Inadequate Response to Etanercept (ENBREL) or Adalimumab (HUMIRA)

Janssen Biotech

NCT01004432

COMPLETED NA 416 participants

Comparing ASHC and CDSMP Outcomes In Arthritis

Centers for Disease Control and Prevention

NCT00207441

COMPLETED NA 400 participants

The Health Access and Recovery Peer Program

Emory University

NCT01725815

COMPLETED NA 395 participants

Trial Outcomes for Massage: Caregiver-Assisted vs. Therapist-Treated

VA Office of Research and Development

NCT03100539

COMPLETED NA 360 participants

Staying Positive With Arthritis Study

VA Office of Research and Development

NCT02223858

COMPLETED NA 360 participants

A Safety and Efficacy Study of the Birmingham Hip Resurfacing System

Smith & Nephew

NCT00611585

COMPLETED NA 236 participants

Study Comparing Marathon Polyethylene and Enduron Polyethylene Acetabular Liners Used in Total Hip Arthroplasty

Anderson Orthopaedic Research Institute

NCT01121146

COMPLETED NA 230 participants

Marathon and Enduron Polyethylene at Long-Term Follow-up

Anderson Orthopaedic Research Institute

NCT02508428

COMPLETED Phase 2 200 participants

Sustained Acoustic Medicine (SAM) for Symptomatic Treatment of Knee Pain Related to Osteoarthritis

ZetrOZ

NCT05882812

COMPLETED Phase 2 154 participants

Fitness and Exercise for People With Arthritis

Centers for Disease Control and Prevention

NCT00252070

COMPLETED NA 132 participants

Ultrasound Guided Arthrocentesis

Wake Forest University Health Sciences

NCT00537589

COMPLETED 102 participants

Regenerex Tibial Tray Multi-Center Data Collection

Zimmer Biomet

NCT00859963

COMPLETED NA 55 participants

Mechanisms of Action of Acetaminophen

University of Pennsylvania

NCT00646906

COMPLETED NA 43 participants

Safety and Efficacy of Gardasil in Females With Juvenile Idiopathic Arthritis (JIA)/Seronegative Arthritis

University Hospitals Cleveland Medical Center

NCT00573651

COMPLETED Phase 1 34 participants

Sustained Acoustic Medicine (SAM) Combined With a Diclofenac Ultrasound Coupling Patch for Knee Osteoarthritis

ZetrOZ

NCT04391842

COMPLETED 33 participants

Modifying Exercise for the COPD Patient

Angela N Fellner PhD CCRP

NCT02143206

COMPLETED Phase 1 30 participants

Study Evaluating the Bioavailability of Naproxen 375 mg in Two Formulations

POZEN

NCT00692055

COMPLETED 29 participants

Followup of Glenoid Fix Utilizing Auto Bone Graft in Shoulder Replacement

University of Nebraska

NCT00670852

COMPLETED Phase 1 27 participants

Biomarker-Linked Outcomes of Cellcept in Lupus Arthritis

Oklahoma Medical Research Foundation

NCT00594932

COMPLETED 22 participants

Allograft Meniscal Arthroplasty for the Treatment of Basal Joint Arthritis of the Thumb

Corewell Health East

NCT01542515

COMPLETED NA 21 participants

Horses and Education as Arthritis Therapy

University of Missouri, Kansas City

NCT03141853

COMPLETED Phase 2 20 participants

A Randomized, Double-Blind, Dose-Response Study of the Safety and Uric Acid Effects of Oral Ulodesine Added to Allopurinol in Subjects With Gout and Concomitant Moderate Renal Insufficiency

BioCryst Pharmaceuticals

NCT01407874

COMPLETED NA 18 participants

Yoga as Self-Care for Arthritis in Minority Communities

National Institutes of Health Clinical Center (CC)

NCT01617421

COMPLETED 15 participants

Long Term Outcomes Follow-up of Glenoid Anchor Peg Component Fixation

University of Nebraska

NCT02983357

COMPLETED Phase 1 9 participants

Pharmacokinetics and Metabolism Study of Radiolabeled BMS-986142 in Healthy Male Subjects

Bristol-Myers Squibb

NCT02880670

Phase Distribution

PhaseTrial count
Early Phase 1 5
Phase 2 6
Phase 3 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Arthritis Trial Landscape

ClinicalTrials.gov lists 49 US studies indexed under Arthritis, and 15 of those are currently open to recruitment — roughly 31% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Arthritis shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 11 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Arthritis is led by National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 49 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Arthritis?

PlainTrial tracks 49 US clinical trials for Arthritis, of which 15 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Arthritis?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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