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NCT07100782 · ClinicalTrials.gov registry record · Phase 3

Estradiol-mediated Inflammation and Central Sensitization in the Pathophysiology of Endometriosis-associated Pelvic Pain

A Phase 3 study of Endometriosis and Pelvic Pain, sponsored by University of Michigan.

Recruiting
Registry status
Phase 3
Development phase
130
Enrollment target
1
Study location

NCT07100782 is a Phase 3 study of Endometriosis and Pelvic Pain that is actively recruiting participants, run by University of Michigan. The registered enrollment target is 130 participants, below the 262-participant average among 48 other Endometriosis trials with a reported enrollment target (50% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT07100782, a Phase 3 study of Endometriosis and Pelvic Pain, is actively recruiting participants, sponsored by University of Michigan.

RECRUITING
Registry status
Phase 3
Development phase
130 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to better understand how hormone suppression with Relugolix Combination-Therapy (CT) affects pelvic pain, inflammation, and pain sensitivity in women with moderate-to-severe endometriosis associated pelvic pain.

Interventions

  • DRUG Relugolix CT

Study Locations (1)

Michigan

  • University of Michigan - Ann Arbor

Trial Details

FieldValue
Enrollment Target 130 participants
Start Date 2025-12-08
Est. Completion 2028-09
Phase Phase 3

Sponsor

University of Michigan

1,327 total trials

What the Registry Record Tells You About NCT07100782

The ClinicalTrials.gov registry entry for NCT07100782 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 130 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 262-participant average among 48 other Endometriosis trials with a reported enrollment target (50% lower). The listed sponsor is University of Michigan, which has 1,327 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Endometriosis appearing as the primary indexed condition, and to 1 intervention - of which Relugolix CT is the first listed.

NCT07100782 reports 1 study location spanning 1 distinct geographic area - top geographies include Michigan.

Frequently Asked Questions

What is clinical trial NCT07100782 about?

NCT07100782 is a clinical study titled "Estradiol-mediated Inflammation and Central Sensitization in the Pathophysiology of Endometriosis-associated Pelvic Pain". The purpose of this study is to better understand how hormone suppression with Relugolix Combination-Therapy (CT) affects pelvic pain, inflammation, and pain sensitivity in women with moderate-to-severe endometriosis associated pelvic pain.

What is the current status of trial NCT07100782?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 130 participants. The study started on 2025-12-08. Estimated completion is 2028-09.

What conditions does trial NCT07100782 study?

This clinical trial studies the following conditions: Endometriosis, Pelvic Pain.

What interventions are being tested in trial NCT07100782?

The interventions under investigation include: Relugolix CT (DRUG).

Who is sponsoring clinical trial NCT07100782?

This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07100782 being conducted?

This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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