Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

237 total trials 167 currently recruiting 68 completed

Trial Pipeline

RECRUITING

Identifying Genome Variants in Non-Obstructive Azoospermia (NOA) or Primary Ovarian Insufficiency (POI)

NCT07357701

RECRUITING Phase 3

Hormone Replacement Therapy in Adolescents With Premature Ovarian Insufficiency

NCT06851754

RECRUITING

Uncovering Genes Behind Cartilage Tumors and Vascular Anomalies Using Genomic Sequencing

NCT06749366

RECRUITING

MEHMO Natural History and Biomarkers

NCT06019182

RECRUITING

A Prospective Natural History Study of Lymphatic Anomalies

NCT05731141

RECRUITING

Establishment of Genomic and Phenotypic Database for Niemann-Pick Disease, Type C

NCT05588167

RECRUITING

Characterization of Dysmorphology in Subjects With Creatine Transporter Deficiency

NCT05600946

RECRUITING

Development of a Wearable Point of Care Monitoring Device for Pediatric Obstructive Sleep Apnea

NCT05052216

RECRUITING

Biorepository in Participants Who Undergo OTC for Gonadotoxic Therapy

NCT05440617

RECRUITING

Study of Skeletal Disorders

NCT05031507

RECRUITING

Gonadal Tissue Freezing for Fertility Preservation in Individuals at Risk for Ovarian Dysfunction, Premature Ovarian Insufficiency and Clinically Indicated Gonadectomy

NCT04948658

RECRUITING

Biochemical and Phenotypical Aspects of Smith-Lemli-Opitz Syndrome and Related Disorders of Cholesterol Metabolism

NCT05047354

RECRUITING

Androgen Receptor, Implications for Health and Wellbeing: Natural History Study of Individuals With Androgen Insensitivity

NCT04708431

RECRUITING

Data Collection Study of Pediatric and Adolescent Gynecology Conditions

NCT04717349

RECRUITING

Long-Term Follow-Up of Survivors of Pediatric Cushing Disease

NCT03831958

RECRUITING

Mirror Neuron Network Dysfunction as an Early Biomarker of Neurodevelopmental Disorder

NCT03307317

RECRUITING

Investigations of Juvenile Neuronal Ceroid Lipofuscinosis

NCT03307304

RECRUITING

Evaluation of Children With Endocrine and Metabolic-Related Conditions

NCT02769975

RECRUITING

Children s Growth and Behavior Study

NCT02390765

RECRUITING

Evaluation of Biochemical Markers and Clinical Investigation of Niemann-Pick Disease, Type C

NCT00344331

RECRUITING

Natural History Study of Patients With Excess Androgen

NCT00250159

RECRUITING Phase 1

Diagnosis of Pheochromocytoma

NCT00004847

RECRUITING

An Investigation of Pituitary Tumors and Related Hypothalmic Disorders

NCT00001595

ACTIVE NOT RECRUITING

The Developmental Origins of Suicide Mortality

NCT03027440

ACTIVE NOT RECRUITING

Skeletal Muscle Biomarkers in People With Fragile Sarcolemmal Muscular Dystrophy

NCT01851447

COMPLETED Phase 2

Colchicine to Suppress Inflammation and Improve Insulin Resistance in Adults and Adolescents With Obesity

NCT05017571

COMPLETED Phase 2

Liraglutide (Saxenda(R)) in Adolescents With Obesity After Sleeve Gastrectomy

NCT04883346

COMPLETED

Pediatric Patients With Metabolic or Other Genetic Disorders

NCT02769949

COMPLETED NA

Determining Age Appropriateness of Children's Products and Toys

NCT02544035

COMPLETED

Pregnancy Eating Attributes Study

NCT02217462

COMPLETED Phase 1

Mifepristone Effects on Glucose Intolerance in Obese/Overweight Adults

NCT01419535

COMPLETED NA

Testing and Calibration of Non-Invasive Optical Imaging Technology for Functional Brain Imaging

NCT01212029

COMPLETED Phase 4

Prevention of Iron Deficiency in Breastfed Infants

NCT01444261

COMPLETED

Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-be

NCT01322529

COMPLETED

Exome Sequencing in Autistic Spectrum Disorder

NCT01059201

COMPLETED Phase 1

Biomarker Validation for Niemann-Pick Disease, Type C: Safety and Efficacy of N-Acetyl Cysteine

NCT00975689

COMPLETED

Global Study of Women's Health

NCT00849173

COMPLETED Phase 2

Sodium Nitroprusside for Blood Pressure Reduction in the ICU (SNP2)

NCT00621816

COMPLETED

Epigenetics in the Aging Process

NCT00242255

COMPLETED NA

FES Assisted Cycling in Children With CP

NCT04688424

COMPLETED NA

Healthy Lifestyles for People With Intellectual Disabilities

NCT00597948

COMPLETED Phase 2

Development of a Non-Invasive Treatment for Uterine Leiomyoma (Fibroids)

NCT00332033

COMPLETED

Effects of Endometriosis on Bone Mineral Density

NCT00291278

COMPLETED

Health Behaviors in School-age Children: A World Health Organization Cross-National Study

NCT00341510

COMPLETED Phase 2

Prevention of Environmental Tobacco Smoke Exposure in Children 0-12 Months Old

NCT00340106

COMPLETED

Hypertonia in Patients With Cerebral Palsy

NCT00123708

COMPLETED

Family Study on Preeclampsia

NCT00344162

COMPLETED Phase 2

Building Healthy Teen Relationships and Reproductive Practices to Increase Intervals Between Pregnancies

NCT00342706

COMPLETED Phase 1

Family Management of Childhood Diabetes Study

NCT00340938

COMPLETED Phase 1

Anthrax Vaccine Clinical Trials

NCT00114621

COMPLETED Phase 3

Medical Treatment of Endometriosis-Associated Pelvic Pain

NCT00229996

COMPLETED

Colpocleisis for Advanced Pelvic Organ Prolapse

NCT00271037

COMPLETED

Evaluation and Treatment of Patients With Connective Tissue Disease

NCT00076830

COMPLETED Phase 1

Inspiratory Muscle Training in Ventilator Dependent Patients

NCT00419458

COMPLETED

Interviewing Children About Past Events: Evaluating the NICHD Interview Protocol

NCT00343018

COMPLETED Phase 2

Managing Recurrent Abdominal Pain

NCT00494260

COMPLETED

Studying Fetal Breathing Patterns

NCT00066976

COMPLETED Phase 4

The Role of 5-alpha Reductase in Mediating Testosterone Actions

NCT00493987

COMPLETED

Study of Inborn Errors of Cholesterol Synthesis and Related Disorders

NCT00046202

COMPLETED Phase 3

Community Trial of Newborn Skin and Umbilical Cord Cleansing on Neonatal Mortality in Nepal

NCT00109616

COMPLETED Phase 2

Treatment of Uterine Fibroids With CDB-2914, an Experimental Selective Progesterone Receptor Antagonist

NCT00044876

COMPLETED Phase 3

Colpopexy and Urinary Reduction Efforts (CARE) Protocol

NCT00065845

COMPLETED NA

Middle Ear Disease Before Age 3, Treatment With Ear Tubes, and Literacy and Attentional Abilities at Ages 9 to 11

NCT00365092

COMPLETED Phase 3

Community Trial of Zinc Supplementation on Preschool Child Mortality and Morbidity in Southern Nepal

NCT00109551

COMPLETED

Estimation of the Carrier Frequency and Incidence of Smith-Lemli-Opitz Syndrome in African Americans

NCT00017732

COMPLETED Phase 2

Hormone Replacement Therapy to Treat Turner Syndrome

NCT00013546

COMPLETED Phase 4

Cystagon to Treat Infantile Neuronal Ceroid Lipofuscinosis

NCT00028262

COMPLETED Phase 1

Improving Bone Health in Adolescent Girls: The Youth Osteoporosis and Understanding Total Health (YOUTH) Study

NCT00067600

COMPLETED NA

Learning to Resolve Family Conflict

NCT00059709

COMPLETED NA

Follow-up of Families in Early Preventive Intervention

NCT00438516

COMPLETED NA

Improving Brain Development in Medically Healthy Premature Infants

NCT00065364

COMPLETED Phase 3

Improving Arm Mobility and Use After Stroke

NCT00057018

COMPLETED Phase 2

Peer Mentors for Adolescents in HIV Affected Families

NCT00056953

COMPLETED NA

Conventional Infertility Treatment vs. Fast Track to IVF

NCT00260091

COMPLETED Phase 2

New Imaging Techniques in the Evaluation of Patients With Ectopic Cushing Syndrome

NCT00001849

COMPLETED Phase 2

Treadmill Training for Spinal Cord Injury

NCT00006429

COMPLETED

Study of Smith-Lemli-Opitz Syndrome

NCT00001721

COMPLETED

The Role of Motion in Infants' Ability to Categorize

NCT00362076

COMPLETED

Fat Tissue Microperfusion to Measure Leptin Secretion and Its Relations With Fat Breakdown in Humans

NCT00001722

COMPLETED

Cervical Volume by Three-Dimensional Ultrasound as a Predictor of Preterm Delivery

NCT00342550

COMPLETED

Establishment of a Perinatal Database and a Bank of Biological Materials

NCT00339235

COMPLETED

Clinical, Biochemical, Histological and Biophysical Parameters in the Prediction of Cerebral Palsy in Patients With Preterm Labor and Premature Rupture of Membranes

NCT00342667

COMPLETED

Fetal Growth Evaluation by Three-Dimensional Ultrasound

NCT00340171

COMPLETED Phase 2

Botulinum Toxin (BOTOX) for Cerebral Palsy

NCT00060957

COMPLETED

Evaluation and Intervention for the Effects of Osteogenesis Imperfecta

NCT00001594

COMPLETED NA

How Shoes With Rocker Soles Affect Walking

NCT00006438

COMPLETED Phase 1

Phase I/II Study of Retroviral-Mediated Transfer of Iduronate-2-Sulfatase Gene Into Lymphocytes of Patients With Mucopolysaccharidosis II (Mild Hunter Syndrome)

NCT00004454

COMPLETED Phase 4

Chronic Pain After Amputation

NCT00006427

COMPLETED

Defining the Genetic Basis for the Development of Primary Pigmented Nodular Adrenocortical Disease (PPNAD) and the Carney Complex

NCT00001452

COMPLETED

Iron Overload in African Americans

NCT00001455

COMPLETED Phase 3

Growth Hormone Therapy in Osteogenesis Imperfecta

NCT00001305

COMPLETED

Dose Response Relationship for Single Doses of Corticotropin Releasing Hormone (CRH) in Normal Volunteers and in Patients With Adrenal Insufficiency

NCT00001180

COMPLETED Phase 3

A Phase III Randomized, Double-Blind, Controlled Study of the Use of Anti-HIV Immune Serum Globulin (HIVIG) for the Prevention of Maternal-Fetal HIV Transmission in Pregnant Women and Newborns Receiving Zidovudine (AZT)

NCT00000751

Phase Distribution

PhaseTrial count
Phase 1 8
Phase 2 13
Phase 3 8
Phase 4 4

What the Pipeline for Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Shows

According to the ClinicalTrials.gov registry, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) is linked to 237 US clinical trials across every stage of research activity. Of those, 167 studies are currently recruiting — about 70% of the sponsor's indexed portfolio — and 68 are already marked complete, representing roughly 29% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

The phase mix for Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) reports 12 late-stage studies (Phase 3 and Phase 4 combined) and 21 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

The top therapeutic focus area indexed for Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) is Pregnancy with 8 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial