Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00621179 · ClinicalTrials.gov registry record · Phase 4
Endometrial Markers and Response of Endometriosis Patients to Prolonged GnRH Agonist Prior to IVF
A Phase 4 study of Infertility and Endometriosis, sponsored by Colorado Center for Reproductive Medicine.
- Completed
- Registry status
- Phase 4
- Development phase
- 37
- Enrollment target
- 1
- Study location
NCT00621179: Completed Phase 4 study of Infertility and Endometriosis, sponsored by Colorado Center for Reproductive Medicine.
NCT00621179 is a Phase 4 study of Infertility and Endometriosis that has completed, run by Colorado Center for Reproductive Medicine. The registered enrollment target is 37 participants, below the 7,589-participant average among 74 other Infertility trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00621179, a Phase 4 study of Infertility and Endometriosis, has completed, sponsored by Colorado Center for Reproductive Medicine.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 37 participants
- Enrollment target
- 1
- Study location
Study Summary
This prospective randomized trial evaluates whether one can predict which infertile women with endometriosis who are candidates for in vitro fertilization will benefit from prolonged therapy with a GnRH agonist by the determination of the absence of endometrial expression of the integrin, alpha v, beta 3 vitronectin. This is a prospective randomized trial in which all patients will undergo endometrial biopsy prior to initiation of ovarian stimulation for in vitro fertilization and then undergo randomization to a three month course of a depot preparation of the GnRH agonist leuprolide acetate in depot suspension prior to ovarian stimulation or standard therapy. prio
Primary Outcome
Number of patients who responded to controlled ovarian stimulation as evidenced by implantation of embryo. Implantation confirmed by ultrasound at 6 1/2 weeks of pregnancy.
Conditions Studied
Interventions
- OTHER No intervention
- DRUG Leuprolide acetate in depot suspension
Study Locations (1)
Colorado
- Colorado Center for Reproductive Medicine - Lone Tree
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 37 participants |
| Start Date | 2003-03 |
| Est. Completion | 2010-01 |
| Phase | Phase 4 |
What the finished NCT00621179 record still lists
NCT00621179 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 37 participants, a relatively small participant target, below the 7,589-participant average among 74 other Infertility trials with a reported enrollment target (100% lower).
The record links to 2 conditions, with Infertility appearing as the primary indexed condition, and to 2 interventions - of which No intervention is the first listed.
NCT00621179 reports a single indexed study location in Colorado.
Frequently Asked Questions
What is clinical trial NCT00621179 about?
NCT00621179 is a clinical study titled "Endometrial Markers and Response of Endometriosis Patients to Prolonged GnRH Agonist Prior to IVF". This prospective randomized trial evaluates whether one can predict which infertile women with endometriosis who are candidates for in vitro fertilization will benefit from prolonged therapy with a GnRH agonist by the determination of the absence of endometrial expression of the integrin, alpha v, b...
What is the current status of trial NCT00621179?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 37 participants. The study started on 2003-03. Estimated completion is 2010-01.
What conditions does trial NCT00621179 study?
This clinical trial studies the following conditions: Infertility, Endometriosis.
What interventions are being tested in trial NCT00621179?
The interventions under investigation include: No intervention (OTHER), Leuprolide acetate in depot suspension (DRUG).
Who is sponsoring clinical trial NCT00621179?
This trial is sponsored by Colorado Center for Reproductive Medicine, which has 7 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00621179 being conducted?
This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Infertility
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00621179's enrollment target sits among peer trials
37 68th of 74 higher than 7 of 74 other Infertility trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Infertility trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
GnRH for Luteal Support in IVF/ICSI/FET Cycles
RECRUITING · Phase 4
-
Randomized Controlled Trial of Combined Letrozole and Clomid (CLC II) Versus Letrozole Alone for Women With Anovulation
ACTIVE NOT RECRUITING · Phase 4
-
Vaginal Compared to Intramuscular Progesterone for Frozen Embryo Transfer
COMPLETED · Phase 4
-
Concomitant Administration of FSH With HCG Improves Oocyte Maturation and Quality Double -Blinded Randomized Trial
COMPLETED · Phase 4
-
Menopur Mixed Protocol
COMPLETED · Phase 4
-
Gamete Treatment to Correct Fertilization Failure
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02800486 · 37 participants · Phase 2
Super Selective Intra-arterial Repeated Infusion of Cetuximab (Erbitux) With Reirradiation for Treatment of Relapsed/Refractory GBM, AA, and AOA
- NCT03173937 · 37 participants · Phase 1
Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS Using CordIn(TM), Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Improve Transplant Outcome
- NCT03295227 · 37 participants · Phase 1
Pembrolizumab in Treating Participants With Unresectable Thymoma or Thymic Cancer
- NCT03401047 · 37 participants · Early Phase 1
Study to Assess Potential Impairments in Estradiol Augmentation of Gonadotropin Secretion in Polycystic Ovary Syndrome
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia